GO_0005783 | OmnibusX

endoplasmic reticulum

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	ALB-B2M+FCGRT	ALBU_HUMAN -	Ligand-Receptor
2	APP-SORL1	A4_HUMAN - SORL_HUMAN	Ligand-Receptor	Signaling by Amyloid-beta precursor protein
3	CYP19A1-GPER1	- GPER1_HUMAN	Ligand-Receptor	Signaling by Steroids
4	GLS2+SLC1A1-GRIK1+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
5	GLS2+SLC1A1-GRIK2+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
6	GLS2+SLC1A1-GRIK3+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
7	GLS+SLC1A1-GRIK1+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
8	GLS+SLC1A1-GRIK2+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
9	GLS+SLC1A1-GRIK3+GRIK5	-	Ligand-Receptor	Signaling by Glutamate
10	HSD3B1-CATSPER3+CATSPERB	-	Ligand-Receptor	Signaling by Progesterone
11	HSD3B1-CATSPER3+CATSPERD	-	Ligand-Receptor	Signaling by Progesterone
12	LRRTM1-NRXN1	LRRT1_HUMAN - NRX1A_HUMAN	Ligand-Receptor	Signaling by Leucine-Rich Repeat Transmembrane Neuronal Protein
13	PLA2G2A-ITGA5+ITGB1	PA2GA_HUMAN -	Ligand-Receptor	Cell adhesion by Phospholipase
14	VEGFA-FLT1+KDR	VEGFA_HUMAN -	Ligand-Receptor	Signaling by Vascular endothelial growth factor
15	VEGFA-KDR	VEGFA_HUMAN - VGFR2_HUMAN	Ligand-Receptor	Signaling by Vascular endothelial growth factor

II. Literature review

Name	endoplasmic reticulum
ID	GO_0005783
collection_id	Cellular component
Exact synonym	ER
Description	The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisternae. The ER takes two forms, rough (or granular), with ribosomes adhering to the outer surface, and smooth (with no ribosomes attached).
External URL
Genes	COL4A3 CALU PRKCA C18orf32 erap_human CERS3 RPS3 ACSBG1 PNLDC1 ITGA8 TMEM131L ANKLE2 USP17L11 CDKAL1 RTN2 RPL34 DNASE1L1 UMOD SPHK2 RNF128 IFNGR2 RBMX2 BAK1 PIP4K2C MBOAT7 ATP7A ERP27 PTP4A1 USP17L22 RPL13 NPC2 ARHGAP5 EDEM2 ELOVL3 DNAJB11 ERLIN1 THBS1 ITPKB MTTP SEL1L TMEM64 DISP3 BECN1 SLC26A11 ALG10 DIAPH2 STAU1 PMEL CD1D BCL2L1 FKBP11 HSPA5 TMED6 KCNQ1 PEX16 COPG1 TMT1A MTMR6 SRD5A3 PRDX4 TPST2 FOS CALR SRP54 RPS7 ANK3 FMN2 TEX2 bag6-ubl4a-get4_human EIF2AK3 RPS8 YIPF5 PDIA4 GIMAP1 VMP1 ZDHHC12 SHISA2 KIF1C MPIG6B SLC39A7 CCDC47 SERPINA2 BNIP1 APBB2 ZDHHC9 ZDHHC6 RNF148 UBXN10 CERKL STUB1 RNF13 CNIH4 AMBP P3H1 LCLAT1 PDE2A SURF4 TMEM97 RHBDD1 TMEM214 GPAT4 GNAZ BAX MGRN1 DUOXA2 CES1P1 TSN ITPR3 SRP72 USP25 MAN1A2 DHCR24 CHRNA3 TICAM2 MGST1 SOAT2 ALG12 CTSF MAL AGPAT3 TMCC3 SDR16C5 CDS2 SNX10 NRXN1 GDPD1 RPN1 NDFIP1 CASQ1 SLC35B4 ELOVL5 ORMDL1 SQLE TRAPPC2B CYBC1 ZFAND2A WDFY4 UBXN4 CRAT USP17L21 UBE2G2 DUOX2 PLOD2 TBL2 HHATL SEZ6 PSEN1 FGFR4 ATP11A TAPBP copii_human PLOD3 HSD17B6 EMD ANP32A DERL2 RPN2 PRKN HMGB1 BCAP31 EXTL2 NCSTN RNFT1 CST7 JAGN1 RPL41 SELENOK GIGYF2 IKBIP USO1 SLC27A1 TRAPPC4 TMEM98 SLC35D3 ANKRD13C TAP1 PDIA5 SULF2 CST3 PLCD4 SYVN1 REEP6 CIDEB EBP NKIRAS1 RPS23 PGRMC2 SCAP NECAB3 EPHB1 DEGS1 KLK6 ABCB9 CLN8 DNASE1L3 TMED4 PCSK9 TMEM129 VEGFA MXRA7 TRAPPC5 FBXO2 P4HA3 AGR3 PDILT UGT1A5 NDFIP2 ABCA8 DBH HAP1 CTTN ITPR2 SPTLC1 CAPN2 PTN CRHBP TMEM33 TMTC2 TIMM50 PARP16 MARCHF1 MBOAT4 S100A7 ELOVL6 L1RE1 RNF139 PLSCR2 HSD17B3 POMT2 DHDDS MYO5A LRAT TMEM235 KCNIP4 SCN5A PDIA3 GDI1 SCARA3 MTMR9 CNBP SLC27A4 CIDEC ICMT RINT1 RCN2 OS9 BNIP3 PINK1 RTN3 RNF186 LINC01547 PIGG ERO1A PCDHA1 HACD2 ACER1 SRP68 TMEM100 LRPAP1 PSENEN BACE2 DBI STAU2 NPTX1 TMEM151A TRAPPC9 SPINK5 CCDC88B VRK2 ECPAS CEMIP GRINA CLEC18A MARCHF5 FNDC4 UBIAD1 REEP2 IFIT2 USP17L24 UGT1A1 DNAJB14 PCK1 KTN1 PSEN2 DNAJC3 ZDHHC1 NUCB2 ATP1A3 PIGQ P4HA2 KDELR2 ZDHHC3 MOSPD2 NT5C3A FKBP9 PTPN1 MAMDC2 CLDN8 RAET1L UBXN1 CCDC88A MSMO1 MAGEA3 ACO1 SEC22C LNPK MYOC VHL HSD3B1 TRIM59 ACSL4 BCL2L10 RNF103 PYCARD HSPA1A PIK3C2B TRAPPC3 APP BCL2 YIF1B ATL2 MGST3 ARB2A TMED3 COPG2 PARK7 CNR2 SIGMAR1 GRN GGT2P LTC4S DHRS1 ELOVL4 FKBP7 SORL1 TENM2 TAB3 SGMS1 WFS1 P4HA1 TTMP RDH14 MINAR2 LARS1 DUOX1 UGT1A6 TMEM247 PIGH MTDH SERPINA1 LAMA3 TMTC4 TMEM50B EXT1 SV2A CYP17A1 NLRP3 ALG3 FUT10 ERAP1 RSAD2 TMED9 FAF1 HLA-C GABARAPL1 MARCHF6 PIGP DLG1 HLA-A ARMC10 CREB3L1 TPD52 FGD5 USP17L5 PDIA6 TRPM4 RCN3 TAPBPL DDOST CASP4 PLP2 YKT6 PIGL FTCD GPC2 CDS1 TOMT TMEM132A P2RY13 SEC63 LPIN1 CTSW ATF6 EXT2 FURIN TMEM30B HSP90B1 TMEM192 SMPD2 USP17L1 OAS1 VAPA RESP18 ZFYVE27 ITGA5 TAS2R16 FA2H CIB1 STIM1 SLC22A5 ACSL3 RETREG1 ELOVL2 CES2 PDCD6 SULF1 ELAVL1 ABCA7 PHEX ATL3 CHI3L1 CRTAP APOE ZDHHC19 POFUT1 HADHB ZNRF4 CPT1C PKHD1 VWF ERG28 STIM2 TMBIM1 SARAF TP53 TBXAS1 STOM VPREB1 DSC2 TECRL SULT2B1 KEAP1 ELOVL7 SLC37A4 EHD4 FKBP9P1 POMT1 PPP1R15B ATP8B1 PORCN MAP2K2 REEP4 CAVIN1 VKORC1L1 PROC TRAPPC2 UFM1 CLN3 TSPO2 RTN4 HYOU1 FMO5 UBQLN1 ERGIC3 ELOVL1 WASHC5 HACE1 GPR37 USP17L8 STX8 ATP10B ATP8A1 ATP2A3 RTN1 TMF1 ACAT1 MESD CLN5 UBA52 UBXN2B TRAM1 RNF149 YBX1 UNC93B1 NPC1 TMEM8B ZDHHC20 SLC36A1 HSD3B2 VCP CGRRF1 OLFM1 RNF5 PHTF2 SDF2 RPS6 ULBP1 TLR9 UFSP2 MIP TMX3 PKD1 ZFYVE1 UTP15 SLC35A2 ATP2C2 AGR2 FGFR3 RPLP0 NCK2 RNF115 PPIB APEX1 AQP11 B2M SEZ6L KCNG3 TOR1B CDNF SLC10A7 USP17L12 STT3B UGT1A9 SEC61B USP17L18 EEF1G ZP2 CREB3L4 AIFM3 HSPBP1 KDELR3 MRAP ZDHHC11B CREG2 SIRT6 PCYT1B RER1 LYPLA1 UGT1A4 CHP1 PIGZ PLEKHF2 AGPAT4 FIBIN SHISA5 PLA2G2A RAET1G PTPN2 HMGCLL1 PKD2L1 ZW10 TMCO1 TLR7 SLC1A1 RPS24 SOAT1 CATSPER3 H6PD PLPP2 STS HSPA1B ITPR1 FATE1 PIEZO1 AGA SSR1 PACS2 PTGS2 TMC8 FBXW7 TRAPPC2L THY1 SIL1 UGT1A7 AHCY KSR1 LRP5 BFAR PGS1 REEP5 SHH FGA ORMDL2 XBP1 NHLRC1 NRROS RNF133 ERGIC2 ATP11B EXTL3 ARL6IP1 CLGN PRNP PLIN2 PLD4 NPHS2 PRKCD MAGT1 IL2RG SPCS3 ABCC12 CYP2D6 TMX4 VAPB PTGIS POMGNT2 PSMG1 TRAPPC6A LRRTM1 MR1 GDPD3 PRAP1 ABI1 TOR3A LDAH CD320 UBE2J2 IER3IP1 DLG4 VASH1 SLC30A1 SGPP2 STEEP1 ZDHHC21 ALDH3A1 SREBF2 ASB11 SLC26A6 MAN1B1 AGMO CNPY2 ERMP1 CANX ALG1L2 TLCD4 KCTD17 TM7SF2 HSD17B11 MANF ATP10A PRSS56 MLC1 SMPD4 CCDC134 TRAPPC6B CLCC1 STBD1 APBB1 KDELR1 TMEM259 BOK ERN1 GPAT3 ABCA4 ALG1 HHAT UGT1A10 LRP6 HSD17B12 LPCAT2 AVPR2 CPED1 RIPK2 TMEM35A PCDHA2 PXDNL EDEM1 SACM1L RTN4R CYB561D2 DPM3 P3H3 HTRA2 PEX3 ATP2C1 MEST RPL18 ZDHHC11 ANO7 CD1C CCDC115 EPHX3 HLA-F SUMF1 PLIN1 CCDC3 SRPX TMEM258 STX18 FKBP8 GLUL ATP10D LEMD2 ATP1A2 TENM1 HACD4 CISD2 CD3E KDR CKAP4 EMID1 GIMAP8 UGT1A8 CES1 MAN1A1 A1CF MAN1C1 SELENOS APH1A TRIM32 RNF19B HMGCR UFL1 YIPF6 RPL24 THBS4 AQP5 HNRNPR GIMAP7 ESYT1 KIFAP3 PEDS1 PUM3 GPER1 USE1 APOC1 RNF183 HS1BP3 USP17L17 SDF2L1 PRCD HSD17B13 DSE TMC6 APOD POMP USP17L23 CUBN CREB3L3 UGT1A3 C19orf12 EEF1B2 TMED2 CLEC2D PGRMC1 HERPUD1 RPL10 LRRK2 FCRLB ZDHHC22 YIPF4 CSH2 LSG1 ALKBH1 PLAAT1 ANGEL1 HACD3 CASP12 CLIC1 LGI1 PLA2G4A REEP1 ACSL1 MARCHF2 SSR4 ADPGK UBXN2A ERO1B EMC8 SEC23B KDSR JMJD8 UGT2B28 UBXN8 ACSL6 ATG4B P4HTM ABCB6 TOR1A LRRC25 AGPAT5 ASPH GLUD1 SERAC1 ERGIC1 ATL1 GBA1 SMIM14 KCNIP3 CALCRL AMBRA1 TRPV4 VKORC1 HM13 KCNRG USP17L3 PDIA2 LPCAT4 DLC1 RRBP1 ZFAND2B APH1B HLA-B NSG1 SGPL1 MRAP2 SMO ZDHHC18 RNF122 PKD2 AHSA1 CTSA TGM2 DPM1 CAV1 HYAL2 CLN6 SSR2 SET SEZ6L2 ZDHHC24 FNDC5 HAX1 DNAJC1 MGST2 CYP19A1 GPAA1 PPP1R15A USP17L19 ERP29 PLAAT3 TPBG PTCHD3 FKBP10 TECR TXNDC12 MSRB3 HYAL3 LRRC59 SCP2 RPL10L TSPO WLS AGPAT1 YWHAE RASGRF2 SEC31A POU2F1 AOC3 TMEM117 BNIP3L GJC1 CPEB4 NENF ZDHHC15 HSPA13 INPP5K SUMF2 CWH43 CYB5R4 UPK1A SEC23IP SCAPER GPR85 DERL1 TMEM230 GPX7 SERP2 SEMA3B TOR1AIP2 PSMF1 PRKCE TFPI HPS6 SEMA4F LOXL2 TCL1A EI24 AIMP1 CYP46A1 MOGS GLYATL2 TMCC2 TMPRSS3 RRS1 EDEM3 ALB DNM1L CERS1 TAP2 TLCD3A POGLUT1 ZDHHC23 FAM20A TMEM30A NTSR1 RPS3A ZDHHC13 MOGAT2 PKMYT1 P4HB CAMLG VPREB3 MIA2 TMED7 RRAS2 FKTN STC2 USP17L15 EBPL CYP2S1 PRSS50 TMEM203 UGT8 SPTSSA LYNX1 IGLL1 TBC1D20 USP17L7 SLC30A9 NCK1 SELENOT DNAJB9 ALOX5AP YTHDC2 ATP2A2 CREB3L2 CERS2 SCYL3 CPQ PLOD1 ZDHHC4 CCR10 DNAJC10 INSIG1 SYNCRIP TAB1 TMEM50A LPGAT1 TRAPPC1 RPL21 BDKRB1 SCD PDCL3 CSH1 DNAJB12 INSIG2 RPL36AL TMED1 RPL27A USP17L13 PRKCSH LACC1 VTN TAFA1 TXNDC5 CREB3 CYB5R3 HTT AMFR P3H4 LMAN1 CLEC18C RGMA MGAT4B NDUFB8 CRELD2 P3H2 GOLT1B USP17L4 PCYT1A SRPK1 UGGT1 SAYSD1 MAP2K1 USP17L20 TMED10 NBEAL2 UBAC2 SAMD8 GIMAP2 LRP2 PNPLA7 CAV3 NSDHL RAB32 AHCYL2 ALG10B FAIM2 HMOX1 TMEM199 SLC39A6 TLCD3B BRSK2 PEF1 STARD4 TXNRD3 METTL9 SERP1 KCNA1 PDZD2 TMTC1 USP17L10 SLC27A3 MS4A4A EEF1D CRABP2 TMTC3 DGAT2 ARSG FLT3 B3GALNT2 PLN ACSL5 ZDHHC14 CTSZ FAF2 SLC22A13 ZDHHC2 ENTPD5 MLEC SEC62 PXDN RNF185 B3GALT5 RPL5 TEX264 NOX4 MGAT4D RAP1GDS1 ASAH1 GASK1A PDE3B PNPLA6 RCN1 MGAT4A CAST MYDGF TUNAR ADIPOQ NPLOC4 GRIK5 VCAM1 ATP11C ERLIN2 TRDN EMC2 SQSTM1 USP20 ERN2 DHCR7 SPAST PDCL2 FKBP2 TMED5 PANX1 PCSK6 HTR1B ADAMTS9 ULBP2 SDF4 TMBIM6 PRXL2B HTN1 UVRAG PROM1 PDE9A GOLT1A SSR3 ZDHHC7 OPRM1 RPL36A NBAS AGPAT2 DDRGK1 G6PC3 RAB1A ORMDL3 CBLN3 UGGT2 KLHL14 DUS2 AUP1 TRAPPC3L CLDN14 FGB PGAP1 LPCAT1 ATP1A1 PEMT SLC27A5 FDFT1 VAC14 GHDC SERPINH1