Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 21 studies | 32% ± 12% | |
astrocyte | 16 studies | 38% ± 19% | |
oligodendrocyte | 15 studies | 37% ± 16% | |
microglial cell | 14 studies | 42% ± 14% | |
macrophage | 13 studies | 42% ± 19% | |
oligodendrocyte precursor cell | 13 studies | 42% ± 15% | |
fibroblast | 13 studies | 27% ± 10% | |
glutamatergic neuron | 11 studies | 47% ± 26% | |
GABAergic neuron | 9 studies | 51% ± 19% | |
epithelial cell | 9 studies | 35% ± 16% | |
adipocyte | 9 studies | 44% ± 15% | |
dendritic cell | 8 studies | 33% ± 13% | |
pericyte | 8 studies | 28% ± 8% | |
smooth muscle cell | 8 studies | 22% ± 6% | |
endothelial cell of lymphatic vessel | 7 studies | 33% ± 9% | |
type I pneumocyte | 7 studies | 31% ± 12% | |
neuron | 6 studies | 46% ± 24% | |
interneuron | 6 studies | 52% ± 25% | |
ciliated cell | 6 studies | 25% ± 6% | |
myeloid cell | 6 studies | 32% ± 13% | |
cardiac muscle cell | 5 studies | 28% ± 5% | |
T cell | 5 studies | 24% ± 7% | |
monocyte | 5 studies | 45% ± 10% | |
club cell | 5 studies | 29% ± 8% | |
type II pneumocyte | 5 studies | 30% ± 7% | |
basal cell | 5 studies | 33% ± 13% | |
granule cell | 4 studies | 38% ± 10% | |
mast cell | 4 studies | 22% ± 6% | |
mesothelial cell | 4 studies | 32% ± 13% | |
GABAergic interneuron | 3 studies | 34% ± 7% | |
mononuclear phagocyte | 3 studies | 25% ± 4% | |
non-classical monocyte | 3 studies | 18% ± 2% | |
GABAergic amacrine cell | 3 studies | 27% ± 8% | |
Mueller cell | 3 studies | 30% ± 9% | |
amacrine cell | 3 studies | 27% ± 6% | |
glycinergic amacrine cell | 3 studies | 24% ± 5% | |
retina horizontal cell | 3 studies | 26% ± 8% | |
retinal cone cell | 3 studies | 25% ± 10% | |
retinal rod cell | 3 studies | 31% ± 3% | |
endothelial cell of vascular tree | 3 studies | 28% ± 12% | |
hepatocyte | 3 studies | 52% ± 13% | |
connective tissue cell | 3 studies | 27% ± 4% | |
ependymal cell | 3 studies | 31% ± 17% | |
B cell | 3 studies | 23% ± 6% | |
alveolar macrophage | 3 studies | 52% ± 12% | |
capillary endothelial cell | 3 studies | 21% ± 4% | |
respiratory goblet cell | 3 studies | 37% ± 12% | |
lymphocyte | 3 studies | 25% ± 8% | |
goblet cell | 3 studies | 33% ± 19% | |
transit amplifying cell | 3 studies | 32% ± 22% | |
kidney loop of Henle epithelial cell | 3 studies | 31% ± 7% | |
renal principal cell | 3 studies | 35% ± 5% | |
mucus secreting cell | 3 studies | 33% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
breast | 100% | 2073.49 | 459 / 459 | 100% | 34.11 | 1118 / 1118 |
ovary | 100% | 1569.24 | 180 / 180 | 100% | 22.17 | 430 / 430 |
prostate | 100% | 1703.36 | 245 / 245 | 100% | 31.16 | 501 / 502 |
thymus | 100% | 2382.65 | 653 / 653 | 100% | 29.06 | 602 / 605 |
kidney | 100% | 2760.97 | 89 / 89 | 99% | 27.58 | 896 / 901 |
bladder | 100% | 1742.62 | 21 / 21 | 99% | 25.65 | 501 / 504 |
pancreas | 99% | 1102.35 | 326 / 328 | 100% | 23.88 | 178 / 178 |
lung | 100% | 1829.11 | 578 / 578 | 99% | 19.46 | 1146 / 1155 |
intestine | 100% | 1579.65 | 966 / 966 | 99% | 18.63 | 522 / 527 |
liver | 100% | 1269.24 | 226 / 226 | 99% | 15.33 | 402 / 406 |
esophagus | 100% | 1777.89 | 1445 / 1445 | 97% | 12.35 | 178 / 183 |
stomach | 100% | 1582.29 | 359 / 359 | 97% | 15.54 | 276 / 286 |
uterus | 100% | 1579.04 | 170 / 170 | 96% | 18.74 | 442 / 459 |
skin | 100% | 2375.64 | 1809 / 1809 | 96% | 17.35 | 454 / 472 |
adrenal gland | 100% | 1981.91 | 258 / 258 | 93% | 16.89 | 215 / 230 |
brain | 91% | 581.98 | 2399 / 2642 | 96% | 11.62 | 675 / 705 |
adipose | 100% | 2045.14 | 1204 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 100% | 10.37 | 29 / 29 |
spleen | 100% | 1706.91 | 241 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 17.23 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 38.60 | 1 / 1 |
blood vessel | 100% | 2111.19 | 1333 / 1335 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 96% | 13.13 | 77 / 80 |
heart | 94% | 762.41 | 812 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 88% | 1075.08 | 821 / 929 | 0% | 0 | 0 / 0 |
muscle | 35% | 148.39 | 285 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0018158 | Biological process | protein oxidation |
GO_0043687 | Biological process | post-translational protein modification |
GO_0046479 | Biological process | glycosphingolipid catabolic process |
GO_0005788 | Cellular component | endoplasmic reticulum lumen |
GO_0005783 | Cellular component | endoplasmic reticulum |
GO_0016491 | Molecular function | oxidoreductase activity |
GO_1903135 | Molecular function | cupric ion binding |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0120147 | Molecular function | formylglycine-generating oxidase activity |
Gene name | SUMF1 |
Protein name | Formylglycine-generating enzyme (FGE) (EC 1.8.3.7) (C-alpha-formylglycine-generating enzyme 1) (Sulfatase-modifying factor 1) Sulfatase modifying factor 1 |
Synonyms | UNQ3037/PRO9852 PSEC0152 |
Description | FUNCTION: Oxidase that catalyzes the conversion of cysteine to 3-oxoalanine on target proteins, using molecular oxygen and an unidentified reducing agent . 3-oxoalanine modification, which is also named formylglycine (fGly), occurs in the maturation of arylsulfatases and some alkaline phosphatases that use the hydrated form of 3-oxoalanine as a catalytic nucleophile . Known substrates include GALNS, ARSA, STS and ARSE . . |
Accessions | ENST00000448413.5 Q8NBK3 ENST00000272902.10 [Q8NBK3-1] ENST00000458465.6 F5GXA0 ENST00000383843.9 [Q8NBK3-4] ENST00000405420.2 [Q8NBK3-5] E9PF05 |