ID | Name | Number of studies | |
---|---|---|---|
CL_0000097 | mast cell | 69 | |
CL_0000766 | myeloid leukocyte | 0 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) | |
---|---|---|---|---|---|
TPSAB1 | 32 | 84% ± 21% | 0 | 1 | |
HDC | 32 | 55% ± 18% | 0 | 1 | |
SLC18A2 | 31 | 59% ± 17% | 0 | 1 | |
MS4A2 | 30 | 66% ± 19% | 0 | 0 | |
ADGRE2 | 21 | 27% ± 12% | 0 | 11 | |
CPA3 | 34 | 83% ± 16% | 1 | 3 | |
IL1RL1 | 28 | 59% ± 22% | 1 | 4 | |
GCSAML | 19 | 31% ± 15% | 1 | 1 | |
RGS13 | 27 | 48% ± 13% | 2 | 3 | |
RHEX | 26 | 53% ± 22% | 2 | 4 | |
ALOX5 | 27 | 46% ± 13% | 2 | 16 | |
PTGS1 | 24 | 35% ± 12% | 2 | 7 | |
GRAP2 | 24 | 39% ± 17% | 2 | 18 | |
BTK | 23 | 36% ± 15% | 2 | 17 | |
LTC4S | 22 | 57% ± 19% | 2 | 13 | |
P2RX1 | 20 | 32% ± 16% | 2 | 10 | |
BATF | 21 | 33% ± 13% | 2 | 23 | |
HPGDS | 35 | 71% ± 18% | 3 | 8 | |
RGS1 | 29 | 53% ± 25% | 3 | 46 | |
SYTL3 | 27 | 46% ± 17% | 3 | 34 | |
GALC | 20 | 33% ± 13% | 3 | 10 | |
TMEM154 | 20 | 26% ± 8% | 3 | 12 | |
TESPA1 | 20 | 31% ± 17% | 3 | 13 | |
GATA2 | 32 | 65% ± 20% | 4 | 10 | |
VWA5A | 31 | 59% ± 18% | 4 | 5 | |
CD69 | 30 | 58% ± 25% | 4 | 54 | |
FCER1G | 27 | 67% ± 20% | 4 | 32 | |
ALOX5AP | 28 | 66% ± 24% | 4 | 53 | |
RHOH | 26 | 44% ± 12% | 4 | 47 | |
TYROBP | 24 | 60% ± 21% | 4 | 40 |
GO_0043306 | Biological process | positive regulation of mast cell degranulation |
GO_0002071 | Biological process | glandular epithelial cell maturation |
GO_0006687 | Biological process | glycosphingolipid metabolic process |
GO_0038109 | Biological process | Kit signaling pathway |
GO_0048170 | Biological process | positive regulation of long-term neuronal synaptic plasticity |
GO_1904251 | Biological process | regulation of bile acid metabolic process |
GO_0051093 | Biological process | negative regulation of developmental process |
GO_1904349 | Biological process | positive regulation of small intestine smooth muscle contraction |
GO_0019372 | Biological process | lipoxygenase pathway |
GO_0038162 | Biological process | erythropoietin-mediated signaling pathway |
GO_0043586 | Biological process | tongue development |
GO_0097154 | Biological process | GABAergic neuron differentiation |
GO_0021902 | Biological process | commitment of neuronal cell to specific neuron type in forebrain |
GO_2000255 | Biological process | negative regulation of male germ cell proliferation |
GO_0002732 | Biological process | positive regulation of dendritic cell cytokine production |
GO_0045650 | Biological process | negative regulation of macrophage differentiation |
GO_0021533 | Biological process | cell differentiation in hindbrain |
GO_0032765 | Biological process | positive regulation of mast cell cytokine production |
GO_0021514 | Biological process | ventral spinal cord interneuron differentiation |
GO_0035701 | Biological process | hematopoietic stem cell migration |
GO_0021954 | Biological process | central nervous system neuron development |
GO_2000242 | Biological process | negative regulation of reproductive process |
GO_0038093 | Biological process | Fc receptor signaling pathway |
GO_0002318 | Biological process | myeloid progenitor cell differentiation |
GO_0002327 | Biological process | immature B cell differentiation |
GO_0002320 | Biological process | lymphoid progenitor cell differentiation |
GO_0008354 | Biological process | germ cell migration |
GO_0002551 | Biological process | mast cell chemotaxis |
GO_0060374 | Biological process | mast cell differentiation |
GO_0007406 | Biological process | negative regulation of neuroblast proliferation |
Cell type name | mast cell |
Synonyms | histaminocyte labrocyte mastocyte |
Description | A cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation. Progenitors leave bone marrow and mature in connective and mucosal tissue. Mature mast cells are found in all tissues, except the bloodstream. Their phenotype is CD117-high, CD123-negative, CD193-positive, CD200R3-positive, and FceRI-high. Stem-cell factor (KIT-ligand; SCF) is the main controlling signal of their survival and development. |
Parent | CL_0000766 |