Name | Number of supported studies | Average coverage | |
---|---|---|---|
mast cell | 32 studies | 55% ± 18% | |
granulocyte | 3 studies | 47% ± 19% |
Insufficient scRNA-seq data for expression of HDC at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 96% | 1513.20 | 553 / 578 | 62% | 2.18 | 714 / 1155 |
stomach | 96% | 2262.48 | 345 / 359 | 36% | 0.83 | 102 / 286 |
bladder | 95% | 856.10 | 20 / 21 | 29% | 0.96 | 145 / 504 |
prostate | 84% | 607.93 | 207 / 245 | 35% | 0.78 | 177 / 502 |
breast | 71% | 339.92 | 328 / 459 | 48% | 10.75 | 539 / 1118 |
esophagus | 81% | 707.31 | 1177 / 1445 | 28% | 0.66 | 51 / 183 |
uterus | 77% | 391.59 | 131 / 170 | 29% | 0.90 | 135 / 459 |
intestine | 72% | 432.14 | 695 / 966 | 30% | 0.70 | 160 / 527 |
adipose | 86% | 679.20 | 1032 / 1204 | 0% | 0 | 0 / 0 |
kidney | 36% | 153.89 | 32 / 89 | 39% | 1.12 | 355 / 901 |
pancreas | 14% | 31.58 | 47 / 328 | 60% | 1.96 | 107 / 178 |
skin | 64% | 490.66 | 1162 / 1809 | 4% | 0.08 | 20 / 472 |
liver | 38% | 82.44 | 86 / 226 | 17% | 0.38 | 67 / 406 |
blood vessel | 38% | 138.88 | 512 / 1335 | 0% | 0 | 0 / 0 |
peripheral blood | 33% | 136.15 | 306 / 929 | 0% | 0 | 0 / 0 |
spleen | 29% | 86.42 | 71 / 241 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 24% | 0.45 | 11 / 45 |
heart | 23% | 46.37 | 194 / 861 | 0% | 0 | 0 / 0 |
ovary | 11% | 32.95 | 20 / 180 | 7% | 0.30 | 30 / 430 |
thymus | 11% | 26.78 | 74 / 653 | 5% | 0.16 | 33 / 605 |
brain | 9% | 843.41 | 232 / 2642 | 7% | 0.27 | 48 / 705 |
adrenal gland | 1% | 1.21 | 2 / 258 | 12% | 0.31 | 28 / 230 |
muscle | 11% | 21.98 | 88 / 803 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 3% | 0.08 | 1 / 29 |
eye | 0% | 0 | 0 / 0 | 1% | 0.02 | 1 / 80 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006520 | Biological process | amino acid metabolic process |
GO_0042423 | Biological process | catecholamine biosynthetic process |
GO_0006547 | Biological process | L-histidine metabolic process |
GO_0006548 | Biological process | L-histidine catabolic process |
GO_0001694 | Biological process | histamine biosynthetic process |
GO_0005829 | Cellular component | cytosol |
GO_0005737 | Cellular component | cytoplasm |
GO_0004398 | Molecular function | histidine decarboxylase activity |
GO_0005515 | Molecular function | protein binding |
GO_0030170 | Molecular function | pyridoxal phosphate binding |
Gene name | HDC |
Protein name | Histidine decarboxylase (HDC) (EC 4.1.1.22) Histidine decarboxylase (EC 4.1.1.22) |
Synonyms | |
Description | FUNCTION: Catalyzes the biosynthesis of histamine from histidine. . |
Accessions | P19113 ENST00000559683.1 ENST00000267845.8 [P19113-1] ENST00000543581.5 [P19113-2] H0YLF0 |