GRAP2 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GRAP2 at tissue level.

III. Associated gene sets

GO_0007165Biological processsignal transduction
GO_0007265Biological processRas protein signal transduction
GO_0043408Biological processregulation of MAPK cascade
GO_0007267Biological processcell-cell signaling
GO_0005768Cellular componentendosome
GO_0005654Cellular componentnucleoplasm
GO_0005829Cellular componentcytosol
GO_0005886Cellular componentplasma membrane
GO_0005737Cellular componentcytoplasm
GO_0005634Cellular componentnucleus
GO_0005515Molecular functionprotein binding
GO_0001784Molecular functionphosphotyrosine residue binding

IV. Literature review

[source]
Gene nameGRAP2
Protein nameGRB2 related adaptor protein 2
GRAP2 protein (GRB2-related adaptor protein 2, isoform CRA_a) (cDNA, FLJ93267, Homo sapiens GRB2-related adaptor protein 2 (GRAP2), mRNA)
GRAP2 protein
GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona)
SynonymsGRB2L
hCG_41723
GADS
GRID
DescriptionFUNCTION: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc.

AccessionsENST00000407075.3 [O75791-1]
Q6FI14
Q6FHA6
ENST00000420971.5
B1AH86
O75791
ENST00000344138.9 [O75791-1]