Name | Number of supported studies | Average coverage | |
---|---|---|---|
mast cell | 24 studies | 39% ± 17% | |
CD8-positive, alpha-beta T cell | 19 studies | 25% ± 9% | |
CD4-positive, alpha-beta T cell | 12 studies | 24% ± 7% | |
T cell | 12 studies | 28% ± 10% | |
platelet | 10 studies | 59% ± 13% | |
naive thymus-derived CD8-positive, alpha-beta T cell | 9 studies | 20% ± 3% | |
CD8-positive, alpha-beta memory T cell | 7 studies | 24% ± 4% | |
effector memory CD8-positive, alpha-beta T cell | 7 studies | 22% ± 6% | |
naive thymus-derived CD4-positive, alpha-beta T cell | 6 studies | 21% ± 5% | |
mucosal invariant T cell | 6 studies | 21% ± 9% | |
regulatory T cell | 6 studies | 21% ± 4% | |
gamma-delta T cell | 6 studies | 26% ± 20% | |
mature NK T cell | 5 studies | 17% ± 2% | |
natural killer cell | 5 studies | 20% ± 3% | |
megakaryocyte | 4 studies | 36% ± 22% | |
effector CD8-positive, alpha-beta T cell | 4 studies | 23% ± 5% | |
effector memory CD8-positive, alpha-beta T cell, terminally differentiated | 4 studies | 23% ± 6% | |
CD4-positive, alpha-beta memory T cell | 4 studies | 21% ± 4% | |
lymphocyte | 3 studies | 44% ± 15% |
Insufficient scRNA-seq data for expression of GRAP2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
lung | 100% | 720.39 | 578 / 578 | 73% | 2.16 | 844 / 1155 |
breast | 92% | 167.34 | 421 / 459 | 68% | 2.09 | 762 / 1118 |
prostate | 98% | 326.72 | 240 / 245 | 60% | 1.28 | 301 / 502 |
stomach | 94% | 204.72 | 339 / 359 | 63% | 1.67 | 181 / 286 |
skin | 66% | 106.94 | 1185 / 1809 | 79% | 4.41 | 375 / 472 |
intestine | 84% | 302.77 | 816 / 966 | 54% | 1.23 | 285 / 527 |
esophagus | 92% | 207.11 | 1329 / 1445 | 43% | 0.95 | 79 / 183 |
bladder | 95% | 283.19 | 20 / 21 | 40% | 0.92 | 200 / 504 |
uterus | 85% | 142.45 | 145 / 170 | 45% | 1.17 | 208 / 459 |
kidney | 61% | 108.52 | 54 / 89 | 59% | 1.49 | 534 / 901 |
thymus | 78% | 150.93 | 512 / 653 | 35% | 15.61 | 214 / 605 |
spleen | 100% | 1374.05 | 241 / 241 | 0% | 0 | 0 / 0 |
peripheral blood | 99% | 2018.39 | 924 / 929 | 0% | 0 | 0 / 0 |
liver | 65% | 108.84 | 146 / 226 | 33% | 0.95 | 136 / 406 |
adipose | 94% | 207.19 | 1129 / 1204 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 86% | 7.61 | 25 / 29 |
pancreas | 20% | 20.70 | 65 / 328 | 65% | 1.86 | 115 / 178 |
tonsil | 0% | 0 | 0 / 0 | 78% | 3.68 | 35 / 45 |
heart | 59% | 103.43 | 511 / 861 | 0% | 0 | 0 / 0 |
ovary | 14% | 15.48 | 25 / 180 | 16% | 0.24 | 67 / 430 |
blood vessel | 28% | 40.69 | 374 / 1335 | 0% | 0 | 0 / 0 |
adrenal gland | 10% | 9.24 | 25 / 258 | 6% | 0.10 | 14 / 230 |
eye | 0% | 0 | 0 / 0 | 13% | 0.25 | 10 / 80 |
brain | 7% | 11.79 | 196 / 2642 | 5% | 0.09 | 33 / 705 |
muscle | 2% | 1.83 | 15 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0007165 | Biological process | signal transduction |
GO_0007265 | Biological process | Ras protein signal transduction |
GO_0043408 | Biological process | regulation of MAPK cascade |
GO_0007267 | Biological process | cell-cell signaling |
GO_0005768 | Cellular component | endosome |
GO_0005654 | Cellular component | nucleoplasm |
GO_0005829 | Cellular component | cytosol |
GO_0005886 | Cellular component | plasma membrane |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0005515 | Molecular function | protein binding |
GO_0001784 | Molecular function | phosphotyrosine residue binding |
Gene name | GRAP2 |
Protein name | GRB2 related adaptor protein 2 GRAP2 protein (GRB2-related adaptor protein 2, isoform CRA_a) (cDNA, FLJ93267, Homo sapiens GRB2-related adaptor protein 2 (GRAP2), mRNA) GRAP2 protein GRB2-related adapter protein 2 (Adapter protein GRID) (GRB-2-like protein) (GRB2L) (GRBLG) (GRBX) (Grf40 adapter protein) (Grf-40) (Growth factor receptor-binding protein) (Hematopoietic cell-associated adapter protein GrpL) (P38) (Protein GADS) (SH3-SH2-SH3 adapter Mona) |
Synonyms | GRB2L hCG_41723 GADS GRID |
Description | FUNCTION: Interacts with SLP-76 to regulate NF-AT activation. Binds to tyrosine-phosphorylated shc. |
Accessions | ENST00000407075.3 [O75791-1] Q6FI14 Q6FHA6 ENST00000420971.5 B1AH86 O75791 ENST00000344138.9 [O75791-1] |