naive thymus-derived CD8-positive, alpha-beta T cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
CD8B1474% ± 17%012
GZMM1348% ± 14%027
ITK1130% ± 8%022
THEMIS1026% ± 5%017
ZAP701137% ± 8%027
FLT3LG1043% ± 14%017
CD8A1465% ± 16%115
TCF71553% ± 19%127
CD3G1460% ± 14%129
FCMR1336% ± 12%127
CD271347% ± 16%130
CD3D1576% ± 21%234
CD961436% ± 10%233
LCK1460% ± 16%234
BCL11B1332% ± 17%227
CD21353% ± 14%235
PASK1028% ± 14%29
TRABD2A1029% ± 12%29
CCR71447% ± 15%317
LEF11349% ± 15%316
CD3E1488% ± 12%337
CD71466% ± 18%337
LAT1344% ± 14%329
GIMAP71459% ± 13%341
SELL1459% ± 19%343
CAMK41337% ± 11%334
DGKA1230% ± 12%420
LTB1568% ± 22%450
CTSW1354% ± 19%431
FYB11568% ± 17%451

III. Associated gene sets

GO_1905581Biological processpositive regulation of low-density lipoprotein particle clearance
GO_0070092Biological processregulation of glucagon secretion
GO_0038110Biological processinterleukin-2-mediated signaling pathway
GO_0006997Biological processnucleus organization
GO_0045324Biological processlate endosome to vacuole transport
GO_0070233Biological processnegative regulation of T cell apoptotic process
GO_0045719Biological processnegative regulation of glycogen biosynthetic process
GO_0034383Biological processlow-density lipoprotein particle clearance
GO_0090205Biological processpositive regulation of cholesterol metabolic process
GO_0043576Biological processregulation of respiratory gaseous exchange
GO_0010458Biological processexit from mitosis
GO_0070670Biological processresponse to interleukin-4
GO_0043392Biological processnegative regulation of DNA binding
GO_0006900Biological processvesicle budding from membrane
GO_1904903Biological processESCRT III complex disassembly
GO_0070669Biological processresponse to interleukin-2

IV. Literature review

[source]
Cell type namenaive thymus-derived CD8-positive, alpha-beta T cell
Synonymsnaive thymus-dervied CD8-positive
alpha-beta T lymphocyte
naive thymus-dervied CD8-positive
alpha-beta T-cell
naive thymus-dervied CD8-positive
alpha-beta T-lymphocyte
DescriptionA CD8-positive, alpha-beta T cell that has not experienced activation via antigen contact and has the phenotype CD45RA-positive, CCR7-positive and CD127-positive. This cell type is also described as being CD25-negative, CD62L-high and CD44-low.
ParentCL_0000625