SELL | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	36 studies	39% ± 13%	Explore
CD4-positive, alpha-beta T cell	29 studies	41% ± 18%	Explore
regulatory T cell	27 studies	49% ± 19%	Explore
plasmacytoid dendritic cell	26 studies	69% ± 17%	Explore
classical monocyte	25 studies	46% ± 17%	Explore
memory B cell	20 studies	43% ± 15%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	20 studies	54% ± 22%	Explore
naive B cell	19 studies	53% ± 15%	Explore
CD8-positive, alpha-beta T cell	18 studies	38% ± 17%	Explore
conventional dendritic cell	16 studies	40% ± 23%	Explore
natural killer cell	15 studies	28% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	59% ± 19%	Explore
T cell	13 studies	37% ± 17%	Explore
neutrophil	13 studies	48% ± 20%	Explore
monocyte	12 studies	42% ± 16%	Explore
CD16-negative, CD56-bright natural killer cell, human	12 studies	63% ± 27%	Explore
gamma-delta T cell	11 studies	35% ± 14%	Explore
CD16-positive, CD56-dim natural killer cell, human	10 studies	33% ± 20%	Explore
dendritic cell	10 studies	44% ± 21%	Explore
CD4-positive, alpha-beta memory T cell	9 studies	43% ± 13%	Explore
plasmablast	7 studies	37% ± 18%	Explore
hematopoietic stem cell	7 studies	56% ± 19%	Explore
effector memory CD8-positive, alpha-beta T cell	6 studies	30% ± 5%	Explore
effector CD8-positive, alpha-beta T cell	6 studies	33% ± 18%	Explore
non-classical monocyte	6 studies	25% ± 5%	Explore
central memory CD8-positive, alpha-beta T cell	5 studies	33% ± 19%	Explore
hematopoietic precursor cell	5 studies	58% ± 18%	Explore
innate lymphoid cell	5 studies	44% ± 20%	Explore
plasma cell	5 studies	37% ± 12%	Explore
myeloid cell	5 studies	42% ± 21%	Explore
T follicular helper cell	5 studies	34% ± 18%	Explore
CD8-positive, alpha-beta memory T cell	5 studies	44% ± 15%	Explore
immature B cell	5 studies	42% ± 16%	Explore
platelet	4 studies	24% ± 9%	Explore
mature NK T cell	4 studies	29% ± 12%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	51% ± 20%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	50% ± 7%	Explore
double negative thymocyte	4 studies	51% ± 23%	Explore
exhausted T cell	3 studies	33% ± 10%	Explore
common myeloid progenitor	3 studies	45% ± 33%	Explore
intermediate monocyte	3 studies	44% ± 23%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	57% ± 15%	Explore
CD4-positive, alpha-beta cytotoxic T cell	3 studies	23% ± 5%	Explore
erythrocyte	3 studies	29% ± 13%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	22 studies	41% ± 15%	Explore
lymph node	5 studies	32% ± 10%	Explore
bone marrow	3 studies	36% ± 17%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	100%	2310.74	576 / 578	85%	23.91	987 / 1155
breast	63%	202.96	288 / 459	81%	28.62	906 / 1118
brain	45%	191.64	1183 / 2642	89%	100.56	628 / 705
thymus	50%	314.11	324 / 653	80%	31.36	487 / 605
bladder	57%	277.33	12 / 21	68%	51.99	344 / 504
kidney	46%	245.31	41 / 89	69%	11.54	625 / 901
peripheral blood	100%	99596.59	929 / 929	0%	0	0 / 0
spleen	100%	13189.54	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	10.38	1 / 1
lymph node	0%	0	0 / 0	97%	189.72	28 / 29
stomach	29%	151.64	105 / 359	66%	13.66	188 / 286
intestine	38%	543.57	369 / 966	52%	11.91	274 / 527
liver	56%	198.39	126 / 226	34%	6.23	138 / 406
pancreas	5%	14.82	16 / 328	85%	27.96	151 / 178
tonsil	0%	0	0 / 0	82%	32.68	37 / 45
adipose	77%	578.49	928 / 1204	0%	0	0 / 0
prostate	32%	108.09	79 / 245	42%	6.23	213 / 502
skin	3%	7.68	47 / 1809	71%	32.81	336 / 472
esophagus	20%	88.89	284 / 1445	53%	10.88	97 / 183
uterus	14%	70.39	24 / 170	57%	13.09	261 / 459
ovary	8%	21.82	14 / 180	52%	6.66	224 / 430
blood vessel	57%	293.70	755 / 1335	0%	0	0 / 0
heart	38%	144.77	325 / 861	0%	0	0 / 0
adrenal gland	12%	27.57	30 / 258	17%	1.61	39 / 230
eye	0%	0	0 / 0	15%	1.51	12 / 80
muscle	5%	12.33	38 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0050901	Biological process	leukocyte tethering or rolling
GO_0007155	Biological process	cell adhesion
GO_0007157	Biological process	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0016339	Biological process	calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0034097	Biological process	response to cytokine
GO_0007159	Biological process	leukocyte cell-cell adhesion
GO_0005615	Cellular component	extracellular space
GO_0030667	Cellular component	secretory granule membrane
GO_0009897	Cellular component	external side of plasma membrane
GO_0005886	Cellular component	plasma membrane
GO_0002020	Molecular function	protease binding
GO_0070492	Molecular function	oligosaccharide binding
GO_0008201	Molecular function	heparin binding
GO_0043208	Molecular function	glycosphingolipid binding
GO_0005509	Molecular function	calcium ion binding
GO_0030246	Molecular function	carbohydrate binding
GO_0005515	Molecular function	protein binding
GO_0033691	Molecular function	sialic acid binding

IV. Literature review

[source]

Gene name	SELL
Protein name	Selectin L L-selectin L-selectin (CD62 antigen-like family member L) (Leukocyte adhesion molecule 1) (LAM-1) (Leukocyte surface antigen Leu-8) (Leukocyte-endothelial cell adhesion molecule 1) (LECAM1) (Lymph node homing receptor) (TQ1) (gp90-MEL) (CD antigen CD62L)
Synonyms	hCG_37088 LNHR LYAM1
Description	FUNCTION: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells . Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia . . FUNCTION: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. . FUNCTION: Calcium-dependent lectin that mediates cell adhesion by binding to glycoproteins on neighboring cells. Mediates the adherence of lymphocytes to endothelial cells of high endothelial venules in peripheral lymph nodes. Promotes initial tethering and rolling of leukocytes in endothelia. .
Accessions	ENST00000236147.6 [P14151-1] A0A494C0S7 ENST00000497295.1 A0A0H5AY34 Q8WW79 P14151 ENST00000650983.1 [P14151-2]

SELL report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review