regulatory T cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
TIGIT2645% ± 16%013
FOXP32444% ± 18%00
CTLA42444% ± 13%03
ICOS2236% ± 9%010
ITK2334% ± 11%022
CD3G2755% ± 16%129
CD272755% ± 16%130
RTKN22431% ± 10%11
IL2RA2436% ± 20%13
GBP52438% ± 16%123
CD282231% ± 7%112
FCMR2344% ± 16%127
CD23063% ± 18%235
CD2472950% ± 14%234
LCK2859% ± 19%234
CD3D2880% ± 14%234
BATF2448% ± 17%223
SKAP12948% ± 17%335
CD72959% ± 18%337
CD3E2883% ± 15%337
SELL2749% ± 19%343
RGS12653% ± 20%346
TRAF3IP32947% ± 17%447
LTB2977% ± 16%450
TNFRSF1B2843% ± 18%445
RHOH2844% ± 13%447
PTPRC3085% ± 9%467
PIM22643% ± 18%436
CYTIP2856% ± 16%457
FYB12764% ± 15%451

III. Associated gene sets

GO_0034316Biological processnegative regulation of Arp2/3 complex-mediated actin nucleation
GO_0070233Biological processnegative regulation of T cell apoptotic process
GO_0032914Biological processpositive regulation of transforming growth factor beta1 production
GO_0072539Biological processT-helper 17 cell differentiation
GO_0032905Biological processtransforming growth factor beta1 production
GO_0035739Biological processCD4-positive, alpha-beta T cell proliferation
GO_0032831Biological processpositive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation
GO_0048289Biological processisotype switching to IgE isotypes
GO_0002677Biological processnegative regulation of chronic inflammatory response
GO_0045069Biological processregulation of viral genome replication
GO_0032792Biological processnegative regulation of CREB transcription factor activity
GO_0045064Biological processT-helper 2 cell differentiation
GO_0033092Biological processpositive regulation of immature T cell proliferation in thymus
GO_0045066Biological processregulatory T cell differentiation
GO_0002532Biological processproduction of molecular mediator involved in inflammatory response
GO_0002513Biological processtolerance induction to self antigen
GO_0072540Biological processT-helper 17 cell lineage commitment
GO_0002870Biological processT cell anergy
GO_0050687Biological processnegative regulation of defense response to virus
GO_0021943Biological processformation of radial glial scaffolds
GO_0032713Biological processnegative regulation of interleukin-4 production
GO_0002669Biological processpositive regulation of T cell anergy
GO_0048302Biological processregulation of isotype switching to IgG isotypes
GO_0048294Biological processnegative regulation of isotype switching to IgE isotypes
GO_0002667Biological processregulation of T cell anergy
GO_1901355Biological processresponse to rapamycin
GO_0033080Biological processimmature T cell proliferation in thymus
GO_0036010Biological processprotein localization to endosome
GO_0030330Biological processDNA damage response, signal transduction by p53 class mediator
GO_2000562Biological processnegative regulation of CD4-positive, alpha-beta T cell proliferation

IV. Literature review

[source]
Cell type nameregulatory T cell
SynonymsTreg
regulatory T lymphocyte
regulatory T-cell
regulatory T-lymphocyte
DescriptionA T cell which regulates overall immune responses as well as the responses of other T cell subsets through direct cell-cell contact and cytokine release.
ParentCL_0002419