T-helper 2 cell differentiation

I. Literature review

[source]
NameT-helper 2 cell differentiation
IDGO_0045064
collection_id

Biological process

Related synonym

T-helper 2 cell development

Description

The process in which a relatively unspecialized T cell acquires specialized features of a T-helper 2 (Th2) cell. A Th2 cell is a CD4-positive, alpha-beta T cell that has the phenotype GATA-3-positive and produces interleukin-4.

Comment

Note that immunologists typically use the word 'development' to refer to cells of B or T cell lineages undergoing the process that GO describes as 'cell differentiation'.

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