BCL3 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
classical monocyte	13 studies	22% ± 8%	Explore
endothelial cell	10 studies	26% ± 9%	Explore
vein endothelial cell	7 studies	22% ± 6%	Explore
fibroblast	6 studies	22% ± 5%	Explore
capillary endothelial cell	6 studies	20% ± 4%	Explore
monocyte	5 studies	26% ± 7%	Explore
conventional dendritic cell	5 studies	24% ± 5%	Explore
endothelial cell of artery	5 studies	21% ± 8%	Explore
pericyte	5 studies	24% ± 6%	Explore
dendritic cell	4 studies	30% ± 16%	Explore
non-classical monocyte	4 studies	23% ± 9%	Explore
epithelial cell	4 studies	34% ± 22%	Explore
endothelial cell of vascular tree	4 studies	30% ± 15%	Explore
plasmacytoid dendritic cell	4 studies	18% ± 4%	Explore
mast cell	3 studies	21% ± 5%	Explore
squamous epithelial cell	3 studies	29% ± 13%	Explore
myeloid cell	3 studies	25% ± 3%	Explore
ciliated cell	3 studies	32% ± 6%	Explore
macrophage	3 studies	20% ± 5%	Explore
smooth muscle cell	3 studies	21% ± 6%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	30% ± 8%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	3 studies	24% ± 8%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
prostate	100%	5452.07	245 / 245	99%	63.72	498 / 502
intestine	99%	4659.66	961 / 966	99%	94.61	524 / 527
uterus	99%	3244.39	169 / 170	99%	115.89	454 / 459
esophagus	98%	4989.31	1415 / 1445	100%	151.60	183 / 183
lung	100%	10182.32	576 / 578	98%	94.23	1134 / 1155
breast	100%	4589.51	458 / 459	98%	79.46	1096 / 1118
bladder	100%	4314.10	21 / 21	96%	82.27	484 / 504
stomach	97%	3324.78	347 / 359	99%	114.14	282 / 286
liver	100%	9642.78	226 / 226	95%	60.15	386 / 406
thymus	99%	4783.47	646 / 653	90%	35.17	547 / 605
ovary	84%	2669.59	151 / 180	99%	116.56	426 / 430
pancreas	86%	2574.34	282 / 328	96%	86.39	171 / 178
kidney	97%	4108.06	86 / 89	85%	40.92	768 / 901
skin	98%	2866.26	1770 / 1809	82%	35.49	387 / 472
adrenal gland	100%	4644.98	258 / 258	61%	21.51	141 / 230
lymph node	0%	0	0 / 0	100%	119.53	29 / 29
spleen	100%	7149.47	241 / 241	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	60.82	1 / 1
peripheral blood	100%	8296.67	925 / 929	0%	0	0 / 0
adipose	99%	5559.03	1196 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	98%	103.78	44 / 45
blood vessel	87%	2668.96	1168 / 1335	0%	0	0 / 0
heart	87%	2417.43	748 / 861	0%	0	0 / 0
muscle	46%	887.60	371 / 803	0%	0	0 / 0
brain	13%	175.29	341 / 2642	26%	9.32	185 / 705
eye	0%	0	0 / 0	31%	8.15	25 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_1901222	Biological process	regulation of non-canonical NF-kappaB signal transduction
GO_0070233	Biological process	negative regulation of T cell apoptotic process
GO_0046426	Biological process	negative regulation of receptor signaling pathway via JAK-STAT
GO_0002467	Biological process	germinal center formation
GO_0042832	Biological process	defense response to protozoan
GO_0010225	Biological process	response to UV-C
GO_0007249	Biological process	canonical NF-kappaB signal transduction
GO_0009615	Biological process	response to virus
GO_0002268	Biological process	follicular dendritic cell differentiation
GO_0006974	Biological process	DNA damage response
GO_0042771	Biological process	intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO_0030198	Biological process	extracellular matrix organization
GO_0032733	Biological process	positive regulation of interleukin-10 production
GO_0032088	Biological process	negative regulation of NF-kappaB transcription factor activity
GO_0070231	Biological process	T cell apoptotic process
GO_0045064	Biological process	T-helper 2 cell differentiation
GO_0051101	Biological process	regulation of DNA binding
GO_0048536	Biological process	spleen development
GO_0002315	Biological process	marginal zone B cell differentiation
GO_0019730	Biological process	antimicrobial humoral response
GO_0030330	Biological process	DNA damage response, signal transduction by p53 class mediator
GO_0042981	Biological process	regulation of apoptotic process
GO_0042088	Biological process	T-helper 1 type immune response
GO_0045893	Biological process	positive regulation of DNA-templated transcription
GO_0043066	Biological process	negative regulation of apoptotic process
GO_0006606	Biological process	protein import into nucleus
GO_0032717	Biological process	negative regulation of interleukin-8 production
GO_0042742	Biological process	defense response to bacterium
GO_0045727	Biological process	positive regulation of translation
GO_0032729	Biological process	positive regulation of type II interferon production
GO_0032720	Biological process	negative regulation of tumor necrosis factor production
GO_0002455	Biological process	humoral immune response mediated by circulating immunoglobulin
GO_0045892	Biological process	negative regulation of DNA-templated transcription
GO_0045944	Biological process	positive regulation of transcription by RNA polymerase II
GO_0030496	Cellular component	midbody
GO_0032996	Cellular component	Bcl3-Bcl10 complex
GO_0005886	Cellular component	plasma membrane
GO_0048471	Cellular component	perinuclear region of cytoplasm
GO_0033257	Cellular component	Bcl3/NF-kappaB2 complex
GO_0032991	Cellular component	protein-containing complex
GO_0005654	Cellular component	nucleoplasm
GO_0005829	Cellular component	cytosol
GO_0005737	Cellular component	cytoplasm
GO_0043231	Cellular component	intracellular membrane-bounded organelle
GO_0005634	Cellular component	nucleus
GO_0140297	Molecular function	DNA-binding transcription factor binding
GO_0003714	Molecular function	transcription corepressor activity
GO_0030674	Molecular function	protein-macromolecule adaptor activity
GO_0003713	Molecular function	transcription coactivator activity
GO_0005515	Molecular function	protein binding
GO_0042826	Molecular function	histone deacetylase binding

IV. Literature review

[source]

Gene name	BCL3
Protein name	BCL3 transcription coactivator B-cell lymphoma 3 protein (BCL-3) (Proto-oncogene BCL3)
Synonyms	D19S37 BCL4
Description	FUNCTION: Contributes to the regulation of transcriptional activation of NF-kappa-B target genes. In the cytoplasm, inhibits the nuclear translocation of the NF-kappa-B p50 subunit. In the nucleus, acts as transcriptional activator that promotes transcription of NF-kappa-B target genes. Contributes to the regulation of cell proliferation (By similarity). .
Accessions	P20749 ENST00000164227.10 ENST00000444487.1 H7C0A2

BCL3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review