ID | Name | Number of studies | |
---|---|---|---|
CL_0000151 | secretory cell | 13 | |
CL_4033058 | luminal hormone-sensing cell of mammary gland | 5 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) | |
---|---|---|---|---|---|
STC2 | 4 | 65% ± 7% | 0 | 0 | |
MUCL1 | 4 | 33% ± 5% | 0 | 0 | |
VTCN1 | 4 | 24% ± 6% | 0 | 1 | |
PTHLH | 4 | 25% ± 7% | 0 | 1 | |
IL20RA | 3 | 21% ± 4% | 0 | 2 | |
LYPD3 | 3 | 24% ± 4% | 0 | 4 | |
ANKRD30A | 4 | 66% ± 11% | 1 | 1 | |
TFF1 | 4 | 33% ± 8% | 1 | 3 | |
PIP | 4 | 38% ± 8% | 1 | 3 | |
TM4SF18 | 4 | 22% ± 4% | 1 | 8 | |
RASEF | 4 | 34% ± 9% | 1 | 8 | |
ZG16B | 4 | 35% ± 12% | 1 | 9 | |
MYBPC1 | 3 | 22% ± 1% | 1 | 1 | |
SPDEF | 3 | 42% ± 16% | 1 | 3 | |
PRLR | 3 | 33% ± 4% | 1 | 4 | |
TMC5 | 4 | 35% ± 8% | 1 | 16 | |
PRSS22 | 3 | 23% ± 8% | 1 | 7 | |
RHOV | 3 | 24% ± 8% | 1 | 8 | |
MUC1 | 4 | 32% ± 6% | 1 | 20 | |
BAMBI | 4 | 34% ± 8% | 2 | 4 | |
IRX3 | 4 | 29% ± 7% | 2 | 6 | |
CRACR2B | 4 | 48% ± 17% | 2 | 11 | |
FBP1 | 4 | 31% ± 10% | 2 | 14 | |
AGR3 | 4 | 49% ± 9% | 2 | 15 | |
SCUBE2 | 4 | 22% ± 7% | 3 | 3 | |
AR | 4 | 36% ± 12% | 3 | 6 | |
DNAJC12 | 4 | 32% ± 11% | 3 | 7 | |
TFAP2A | 4 | 35% ± 3% | 3 | 9 | |
AK5 | 4 | 23% ± 3% | 3 | 9 | |
ACADSB | 4 | 27% ± 4% | 3 | 10 |
GO_0140694 | Biological process | non-membrane-bounded organelle assembly |
GO_0038161 | Biological process | prolactin signaling pathway |
GO_0048808 | Biological process | male genitalia morphogenesis |
GO_0042976 | Biological process | activation of Janus kinase activity |
GO_0048645 | Biological process | animal organ formation |
GO_0045726 | Biological process | positive regulation of integrin biosynthetic process |
GO_0070233 | Biological process | negative regulation of T cell apoptotic process |
GO_0060736 | Biological process | prostate gland growth |
GO_0030520 | Biological process | estrogen receptor signaling pathway |
GO_0030856 | Biological process | regulation of epithelial cell differentiation |
GO_0060644 | Biological process | mammary gland epithelial cell differentiation |
GO_0097011 | Biological process | cellular response to granulocyte macrophage colony-stimulating factor stimulus |
GO_0060748 | Biological process | tertiary branching involved in mammary gland duct morphogenesis |
Cell type name | luminal hormone-sensing cell of mammary gland |
Synonyms | ER-positive luminal hormone-sensor cell |
Description | A luminal epithelial cell of the mammary gland that transduces endocrine cues to orchestrate proliferation, architectural remodeling, and differentiation of other cells in the mammary gland via paracrine signaling. This cell expresses high levels of estrogen receptors. In humans, a luminal hormone-sensing cell can be identified by high levels of EpCAM and low levels of CD49f, and in mice it can be identified by low levels of CD29 and high levels of Foxa1, CD133, and Sca1 (Ly6a). |
Parent | CL_0000151 |