PRSS22 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
ciliated cell	7 studies	29% ± 13%	Explore
secretory cell	7 studies	41% ± 16%	Explore
epithelial cell	6 studies	44% ± 11%	Explore
basal cell	6 studies	35% ± 16%	Explore
respiratory goblet cell	4 studies	30% ± 9%	Explore
squamous epithelial cell	4 studies	65% ± 22%	Explore
club cell	3 studies	28% ± 8%	Explore
luminal hormone-sensing cell of mammary gland	3 studies	23% ± 8%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lung	3 studies	32% ± 22%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	100%	772.59	328 / 328	94%	75.52	168 / 178
lung	94%	511.93	541 / 578	89%	44.78	1030 / 1155
prostate	91%	1437.58	224 / 245	89%	21.35	446 / 502
thymus	100%	534.96	651 / 653	74%	17.32	448 / 605
stomach	75%	650.94	268 / 359	87%	35.38	250 / 286
bladder	57%	412.76	12 / 21	90%	56.20	452 / 504
breast	59%	464.45	273 / 459	84%	21.10	934 / 1118
esophagus	43%	2974.26	626 / 1445	90%	60.36	164 / 183
kidney	100%	1094.78	89 / 89	5%	1.11	47 / 901
intestine	12%	31.96	112 / 966	93%	41.37	492 / 527
uterus	12%	170.06	21 / 170	83%	73.06	379 / 459
tonsil	0%	0	0 / 0	93%	60.08	42 / 45
ovary	2%	2.84	3 / 180	73%	19.22	312 / 430
skin	67%	282.59	1216 / 1809	5%	0.90	23 / 472
liver	25%	43.13	56 / 226	13%	7.85	51 / 406
brain	13%	29.60	335 / 2642	0%	0	0 / 705
adrenal gland	1%	1.53	2 / 258	1%	0.45	3 / 230
adipose	2%	5.38	22 / 1204	0%	0	0 / 0
peripheral blood	1%	3.57	6 / 929	0%	0	0 / 0
spleen	0%	1.94	1 / 241	0%	0	0 / 0
blood vessel	0%	0.26	2 / 1335	0%	0	0 / 0
muscle	0%	1.01	1 / 803	0%	0	0 / 0
heart	0%	0.24	1 / 861	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
eye	0%	0	0 / 0	0%	0	0 / 80
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1