GO_0030330 | DNA damage response, signal transduction by p53 class mediator | OmnibusX

DNA damage response, signal transduction by p53 class mediator

I. Involved cell types

	Genes	Cell types	No. of supported studies
Group 1	MIF BCL3 TP53 USP10 TRIAP1 NBN ATRX SP100 MDM4	epithelial cell	5 studies
Group 2	PPM1D ACER2 PAXIP1 HIPK2 MYO6 FOXO3	dopaminergic neuron glutamatergic neuron	6 studies
Group 3	BATF	regulatory T cell mast cell	41 studies
Group 4	NDRG1 MUC1	epithelial cell secretory cell	17 studies
Group 5	SESN2	epithelial cell endocrine cell lymphocyte neuron	5 studies

II. Literature review

Name	DNA damage response, signal transduction by p53 class mediator
ID	GO_0030330
collection_id	Biological process
Alternative ID	GO:0006976
Description	A cascade of processes induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of DNA damage.
Related synonym	DNA damage response, activation of p53, TP53 signaling pathway, p53 signaling pathway
External URL
Genes	MYO6 FOXO3 MUC1 TP53 USP10 BATF ACER2 BCL3 MIF TRIAP1 SESN2 NBN ATRX MDM4 HIPK2 PPM1D PAXIP1 SP100 NDRG1