Name | Number of supported studies | Average coverage | |
---|---|---|---|
endothelial cell | 43 studies | 34% ± 13% | |
endothelial cell of lymphatic vessel | 22 studies | 37% ± 14% | |
fibroblast | 21 studies | 27% ± 10% | |
pericyte | 19 studies | 36% ± 19% | |
oligodendrocyte | 15 studies | 48% ± 15% | |
epithelial cell | 15 studies | 40% ± 17% | |
basal cell | 15 studies | 30% ± 18% | |
endothelial cell of vascular tree | 14 studies | 47% ± 19% | |
vein endothelial cell | 13 studies | 44% ± 18% | |
type I pneumocyte | 11 studies | 29% ± 10% | |
endothelial cell of artery | 10 studies | 35% ± 7% | |
capillary endothelial cell | 9 studies | 30% ± 9% | |
astrocyte | 9 studies | 26% ± 8% | |
goblet cell | 9 studies | 35% ± 14% | |
classical monocyte | 8 studies | 22% ± 7% | |
epithelial cell of proximal tubule | 8 studies | 30% ± 12% | |
plasmacytoid dendritic cell | 8 studies | 21% ± 4% | |
enterocyte | 7 studies | 41% ± 16% | |
retina horizontal cell | 6 studies | 65% ± 11% | |
smooth muscle cell | 5 studies | 21% ± 3% | |
progenitor cell | 5 studies | 32% ± 14% | |
renal principal cell | 5 studies | 61% ± 10% | |
club cell | 5 studies | 35% ± 20% | |
secretory cell | 5 studies | 37% ± 18% | |
mesothelial cell | 5 studies | 26% ± 9% | |
adipocyte | 5 studies | 26% ± 17% | |
oligodendrocyte precursor cell | 5 studies | 24% ± 11% | |
macrophage | 4 studies | 20% ± 5% | |
enteroendocrine cell | 4 studies | 24% ± 5% | |
abnormal cell | 4 studies | 35% ± 14% | |
kidney distal convoluted tubule epithelial cell | 4 studies | 38% ± 12% | |
kidney loop of Henle epithelial cell | 4 studies | 21% ± 4% | |
type II pneumocyte | 4 studies | 19% ± 3% | |
Mueller cell | 4 studies | 23% ± 4% | |
luminal cell of prostate epithelium | 4 studies | 49% ± 5% | |
keratinocyte | 4 studies | 52% ± 8% | |
T cell | 3 studies | 28% ± 11% | |
monocyte | 3 studies | 26% ± 7% | |
kidney connecting tubule epithelial cell | 3 studies | 52% ± 16% | |
neuron | 3 studies | 28% ± 16% | |
transit amplifying cell | 3 studies | 35% ± 24% | |
extravillous trophoblast | 3 studies | 28% ± 11% | |
myeloid cell | 3 studies | 24% ± 4% | |
ciliated cell | 3 studies | 32% ± 10% | |
glial cell | 3 studies | 22% ± 2% | |
lymphocyte | 3 studies | 29% ± 10% | |
glutamatergic neuron | 3 studies | 25% ± 3% | |
connective tissue cell | 3 studies | 31% ± 5% | |
adventitial cell | 3 studies | 24% ± 2% | |
Schwann cell | 3 studies | 47% ± 15% |
Name | Number of supported studies | Average coverage | |
---|---|---|---|
brain | 10 studies | 29% ± 12% | |
lung | 8 studies | 20% ± 5% | |
intestine | 8 studies | 20% ± 4% | |
kidney | 6 studies | 25% ± 7% | |
prostate | 5 studies | 23% ± 5% | |
uterus | 4 studies | 25% ± 6% | |
eye | 4 studies | 25% ± 9% | |
esophagus | 4 studies | 35% ± 17% | |
skin | 4 studies | 33% ± 6% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
prostate | 100% | 40391.60 | 245 / 245 | 100% | 406.09 | 500 / 502 |
kidney | 100% | 36654.93 | 89 / 89 | 91% | 456.37 | 823 / 901 |
lung | 99% | 23757.78 | 575 / 578 | 86% | 293.71 | 994 / 1155 |
esophagus | 100% | 36813.01 | 1444 / 1445 | 82% | 295.65 | 150 / 183 |
uterus | 98% | 18712.02 | 167 / 170 | 79% | 302.03 | 364 / 459 |
bladder | 100% | 20815.48 | 21 / 21 | 76% | 170.49 | 383 / 504 |
intestine | 100% | 22483.80 | 964 / 966 | 75% | 95.32 | 396 / 527 |
ovary | 100% | 24430.32 | 180 / 180 | 74% | 104.35 | 318 / 430 |
stomach | 99% | 22541.12 | 357 / 359 | 67% | 77.39 | 192 / 286 |
skin | 100% | 46433.26 | 1805 / 1809 | 58% | 134.92 | 272 / 472 |
breast | 100% | 25200.42 | 458 / 459 | 46% | 74.20 | 517 / 1118 |
brain | 84% | 19885.64 | 2207 / 2642 | 50% | 57.04 | 356 / 705 |
adrenal gland | 99% | 13667.95 | 255 / 258 | 33% | 45.77 | 75 / 230 |
thymus | 99% | 17899.88 | 648 / 653 | 19% | 13.25 | 112 / 605 |
pancreas | 40% | 3531.52 | 130 / 328 | 75% | 103.90 | 133 / 178 |
adipose | 100% | 32489.71 | 1202 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 100% | 24758.00 | 1329 / 1335 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 98% | 512.39 | 44 / 45 |
heart | 81% | 11337.11 | 697 / 861 | 0% | 0 | 0 / 0 |
spleen | 76% | 6699.85 | 183 / 241 | 0% | 0 | 0 / 0 |
liver | 37% | 6433.92 | 83 / 226 | 31% | 43.48 | 124 / 406 |
eye | 0% | 0 | 0 / 0 | 61% | 58.42 | 49 / 80 |
peripheral blood | 59% | 8266.70 | 544 / 929 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 24% | 18.61 | 7 / 29 |
muscle | 15% | 1181.36 | 120 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0008285 | Biological process | negative regulation of cell population proliferation |
GO_0010038 | Biological process | response to metal ion |
GO_0007165 | Biological process | signal transduction |
GO_0032287 | Biological process | peripheral nervous system myelin maintenance |
GO_0045576 | Biological process | mast cell activation |
GO_0071456 | Biological process | cellular response to hypoxia |
GO_0030330 | Biological process | DNA damage response, signal transduction by p53 class mediator |
GO_0005886 | Cellular component | plasma membrane |
GO_0005874 | Cellular component | microtubule |
GO_0048471 | Cellular component | perinuclear region of cytoplasm |
GO_0005813 | Cellular component | centrosome |
GO_0070062 | Cellular component | extracellular exosome |
GO_0055038 | Cellular component | recycling endosome membrane |
GO_0005829 | Cellular component | cytosol |
GO_0005912 | Cellular component | adherens junction |
GO_0015630 | Cellular component | microtubule cytoskeleton |
GO_0005737 | Cellular component | cytoplasm |
GO_0005634 | Cellular component | nucleus |
GO_0043015 | Molecular function | gamma-tubulin binding |
GO_0045296 | Molecular function | cadherin binding |
GO_0031267 | Molecular function | small GTPase binding |
GO_0008017 | Molecular function | microtubule binding |
GO_0005515 | Molecular function | protein binding |
Gene name | NDRG1 |
Protein name | Protein NDRG1 (N-myc downstream-regulated gene 1 protein) N-myc downstream regulated 1 Protein NDRG1 (Differentiation-related gene 1 protein) (DRG-1) (N-myc downstream-regulated gene 1 protein) (Nickel-specific induction protein Cap43) (Reducing agents and tunicamycin-responsive protein) (RTP) (Rit42) |
Synonyms | DRG1 CAP43 RTP |
Description | FUNCTION: Stress-responsive protein involved in hormone responses, cell growth, and differentiation. Acts as a tumor suppressor in many cell types. Necessary but not sufficient for p53/TP53-mediated caspase activation and apoptosis. Has a role in cell trafficking, notably of the Schwann cell, and is necessary for the maintenance and development of the peripheral nerve myelin sheath. Required for vesicular recycling of CDH1 and TF. May also function in lipid trafficking. Protects cells from spindle disruption damage. Functions in p53/TP53-dependent mitotic spindle checkpoint. Regulates microtubule dynamics and maintains euploidy. . |
Accessions | ENST00000519580.6 ENST00000675600.1 ENST00000676064.1 E5RGM5 ENST00000537882.3 A0A7I2ST14 A0A6Q8PFB3 E5RG99 E5RJ98 ENST00000519228.5 ENST00000675568.1 E5RH82 ENST00000674521.1 ENST00000520943.5 A0A6Q8PFG2 ENST00000675983.1 A0A6Q8PGD3 ENST00000523892.5 A0A6Q8PF06 E5RI76 E5RIR1 A0A6Q8PGF1 ENST00000518480.5 A0A6Q8PFP2 E5RGG6 ENST00000323851.13 [Q92597-1] A0A6Q8PF28 A0A6Q8PF71 ENST00000675357.1 ENST00000521544.5 A0A6Q8PF16 ENST00000517599.5 ENST00000522377.5 ENST00000675068.1 E5RK17 ENST00000520230.5 ENST00000674925.1 ENST00000674902.1 ENST00000522890.5 ENST00000676005.1 ENST00000518066.5 ENST00000674804.1 ENST00000674605.1 ENST00000414097.6 [Q92597-1] E7ESM1 Q92597 ENST00000676222.1 A0A6Q8PHF2 E5RIM2 ENST00000522738.1 E5RIV1 E5RJY1 ENST00000674839.1 A0A6Q8PFR8 A0A6Q8PGJ1 ENST00000518176.5 ENST00000676375.1 ENST00000522476.5 [Q92597-2] ENST00000675172.1 A0A6Q8PHI0 |