keratinocyte report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
PKP1544% ± 20%01
DSG3532% ± 14%02
KRT14567% ± 27%02
DSC3559% ± 19%03
LYPD3548% ± 27%04
DSG1441% ± 19%00
LGALS7B472% ± 22%01
TP63433% ± 13%01
SPRR1B420% ± 3%02
KRT16447% ± 15%03
COL17A1437% ± 7%03
CCL27360% ± 22%00
SBSN352% ± 12%00
KRTDAP364% ± 18%00
LGALS7341% ± 7%01
GJB3320% ± 5%01
TNS4340% ± 14%02
KRT6A344% ± 20%03
PKP3333% ± 14%05
SERPINB5557% ± 29%14
LY6D570% ± 19%16
TRIM29552% ± 17%18
AHNAK2425% ± 8%14
DENND2C427% ± 7%15
FGFBP1443% ± 19%15
KRT15449% ± 22%16
RHOV437% ± 22%18
KRT5565% ± 15%26
MPZL2528% ± 18%213
DAPL1432% ± 15%25

III. Associated gene sets

GO_0002043Biological processblood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO_0043276Biological processanoikis
GO_0051546Biological processkeratinocyte migration
GO_0010868Biological processnegative regulation of triglyceride biosynthetic process
GO_0010830Biological processregulation of myotube differentiation
GO_0009913Biological processepidermal cell differentiation
GO_0042633Biological processhair cycle
GO_0051729Biological processgermline cell cycle switching, mitotic to meiotic cell cycle
GO_0051290Biological processprotein heterotetramerization
GO_0032792Biological processnegative regulation of CREB transcription factor activity
GO_0032525Biological processsomite rostral/caudal axis specification

IV. Literature review

[source]
Cell type namekeratinocyte
Synonymskeratinized cell of epidermis
malpighian cell
DescriptionAn epidermal cell which synthesizes keratin and undergoes a characteristic change as it moves upward from the basal layers of the epidermis to the cornified (horny) layer of the skin. Successive stages of differentiation of the keratinocytes forming the epidermal layers are basal cell, spinous or prickle cell, and the granular cell.
ParentCL_0000076