I. Expression across cell types
Name | Number of supported studies  | Average coverage | |
|---|---|---|---|
| basal cell | 10 studies | 44% ± 19% | |
| squamous epithelial cell | 4 studies | 47% ± 12% | |
| epithelial cell | 4 studies | 51% ± 28% | |
| keratinocyte | 3 studies | 44% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| basal cell | 10 studies | 44% ± 19% | |
| squamous epithelial cell | 4 studies | 47% ± 12% | |
| epithelial cell | 4 studies | 51% ± 28% | |
| keratinocyte | 3 studies | 44% ± 20% |
Name | Number of supported studies | Average coverage | |
|---|---|---|---|
| esophagus | 4 studies | 41% ± 27% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| esophagus | 44% | 212943.78 | 643 / 1445 | 61% | 4257.14 | 111 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 96% | 6829.29 | 43 / 45 |
| skin | 77% | 26015.02 | 1393 / 1809 | 10% | 479.74 | 46 / 472 |
| uterus | 4% | 7793.05 | 7 / 170 | 55% | 2886.59 | 252 / 459 |
| lung | 9% | 234.99 | 53 / 578 | 40% | 1813.90 | 459 / 1155 |
| bladder | 5% | 51.71 | 1 / 21 | 24% | 988.23 | 121 / 504 |
| pancreas | 2% | 55.98 | 5 / 328 | 12% | 219.76 | 22 / 178 |
| prostate | 11% | 376.63 | 27 / 245 | 0% | 0 | 0 / 502 |
| breast | 4% | 92.07 | 17 / 459 | 3% | 39.11 | 30 / 1118 |
| adipose | 6% | 196.70 | 68 / 1204 | 0% | 0 | 0 / 0 |
| ovary | 3% | 70.16 | 6 / 180 | 2% | 7.75 | 7 / 430 |
| intestine | 1% | 17.20 | 7 / 966 | 4% | 145.86 | 20 / 527 |
| thymus | 2% | 69.81 | 16 / 653 | 1% | 14.44 | 8 / 605 |
| stomach | 3% | 399.70 | 9 / 359 | 1% | 2.18 | 2 / 286 |
| adrenal gland | 2% | 28.59 | 5 / 258 | 0% | 0 | 0 / 230 |
| spleen | 2% | 31.02 | 4 / 241 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 56.70 | 18 / 1335 | 0% | 0 | 0 / 0 |
| kidney | 1% | 20.36 | 1 / 89 | 0% | 0 | 0 / 901 |
| muscle | 1% | 60.40 | 8 / 803 | 0% | 0 | 0 / 0 |
| peripheral blood | 1% | 50.45 | 9 / 929 | 0% | 0 | 0 / 0 |
| brain | 1% | 14.03 | 20 / 2642 | 0% | 0 | 0 / 705 |
| heart | 1% | 11.26 | 5 / 861 | 0% | 0 | 0 / 0 |
| liver | 0% | 3.61 | 1 / 226 | 0% | 0 | 0 / 406 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0008284 | Biological process | positive regulation of cell population proliferation |
| GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
| GO_0031640 | Biological process | killing of cells of another organism |
| GO_0045109 | Biological process | intermediate filament organization |
| GO_0031424 | Biological process | keratinization |
| GO_2000536 | Biological process | negative regulation of entry of bacterium into host cell |
| GO_0050830 | Biological process | defense response to Gram-positive bacterium |
| GO_0002009 | Biological process | morphogenesis of an epithelium |
| GO_0030154 | Biological process | cell differentiation |
| GO_0042060 | Biological process | wound healing |
| GO_0070062 | Cellular component | extracellular exosome |
| GO_0005829 | Cellular component | cytosol |
| GO_0045095 | Cellular component | keratin filament |
| GO_0016020 | Cellular component | membrane |
| GO_0005634 | Cellular component | nucleus |
| GO_0005200 | Molecular function | structural constituent of cytoskeleton |
| GO_0030280 | Molecular function | structural constituent of skin epidermis |
| GO_0005515 | Molecular function | protein binding |
| Gene name | KRT6A |
| Protein name | Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK-6A) (Cytokeratin-6D) (CK-6D) (Keratin-6A) (K6A) (Type-II keratin Kb6) (allergen Hom s 5) Keratin 6A isoform 2 HCG2039812, isoform CRA_b (Keratin 6A isoform 1) |
| Synonyms | hCG_2039812 K6A KRT6D |
| Description | FUNCTION: Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair. . |
| Accessions | A0A0S2Z428 ENST00000330722.7 A0A0S2Z427 P02538 |
