cell differentiation

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1DLK1-NOTCH4DLK1_HUMAN - NOTC4_HUMANLigand-ReceptorSignaling by Notch
2DLL1-NOTCH4DLL1_HUMAN - NOTC4_HUMANLigand-ReceptorSignaling by Notch
3DLL3-NOTCH4DLL3_HUMAN - NOTC4_HUMANLigand-ReceptorSignaling by Notch
4INHA-ACVR1C+ACVR2AINHA_HUMAN - Ligand-ReceptorSignaling by Inhibin/Activin
5INHA-ACVR1C+ACVR2BINHA_HUMAN - Ligand-ReceptorSignaling by Inhibin/Activin
6INHA+INHBA-ACVR1C+ACVR2A - Ligand-ReceptorSignaling by Inhibin/Activin
7INHA+INHBA-ACVR1C+ACVR2B - Ligand-ReceptorSignaling by Inhibin/Activin
8INHA+INHBB-ACVR1C+ACVR2A - Ligand-ReceptorSignaling by Inhibin/Activin
9INHA+INHBB-ACVR1C+ACVR2B - Ligand-ReceptorSignaling by Inhibin/Activin
10INHBA+INHBB-ACVR1C+ACVR2A - Ligand-ReceptorSignaling by Inhibin/Activin
11INHBA+INHBB-ACVR1C+ACVR2B - Ligand-ReceptorSignaling by Inhibin/Activin
12JAG2-NOTCH4JAG2_HUMAN - NOTC4_HUMANLigand-ReceptorSignaling by Notch
13PGF-FLT1PLGF_HUMAN - VGFR1_HUMANLigand-ReceptorSignaling by Placenta growth factor
14PGF-FLT1+KDRPLGF_HUMAN - Ligand-ReceptorSignaling by Placenta growth factor
15TNFSF12-TNFRSF12ATNF12_HUMAN - TNR12_HUMANLigand-ReceptorSignaling by Tumor necrosis factor

II. Literature review

[source]
Namecell differentiation
IDGO_0030154
collection_id

Biological process

Description

The cellular developmental process in which a relatively unspecialized cell, e.g. embryonic or regenerative cell, acquires specialized structural and/or functional features that characterize a specific cell. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.

External URL
Genes
THRAFOXL3ZNF268CSRP2SPMAP2EID1TCF4FGF6PRAMEPRRC2ANR2E1ROS1SRD5A2MEF2ANHSL1ELAVL3NME1AFG2ARARBELK3FOXD2DUSP6FSTL3MYT1NR1I2NR2C2DISP3NTRK3NKX2-6TNFSF12DAZ3HTATIP2FEVETV5SUV39H2CATSPERBRIPOR2CXCL17SYT3SPATA31C1VAMP5SH3PXD2BNLRP14ERGNR1H3FSTL5EDARADDSYT4ELF3PTK6TWIST2SPATA31E1PGFTSPY8FOXE1ID4EYA4GADD45BTSPY2NPAS4SRCSPDEFCATSPERGFOXQ1MALSIM1DLEC1SMOC1SLC22A16TLL2MEA1DAZAP1NKX6-3ETS1SPATA31A5SPATA31D1ADAM18DDX3YSCXTMEM176BSETXMKRN2SPATA31A6PDLIM7NEDD4LCAVIN4SRPK2PRSS42PHNF4ASEPTIN2SYT1RIMS1FOXJ2CDC20CNMDGGNDAPL1OSR2TESCBAG6ZNF750NKAPLNR2E3SMAD5OSR1PRKD1NR2C1NR1I3DAZ4ETV7ZNF423SMAD3NKX1-2FKBP6COL15A1SRA1RAI14EDARSMAD9FSTL4FOXD4L5FCRLAUTP14CJAK2SPIBSPATA31D3NR2F2SYT2NR1D2ACER1RHOBNR1H2FSTACVR1CNKX2-2UBE2V1DPYSL2ARHGAP22ZHX3TAF7LSPINK5SPATA31A7TDRD9GADD45GBMP1TEX15PLET1ZNF808GABPAMYCBPAPHMX3ALKBH5NKX2-8MEF2BANGPTL6SPATA6LARP7SYT17NR1D1JAG2GNA13NIBAN2KRT6ASYT14P1INHBAFOXD1FYNID3ABHD5FGF22GGNBP2TAF8CYLC2CPNE6SPATA31C2APOLD1EYA1ELF1SPATA25NHLH1CLPTM1APAF1FAM209BNANOGFOXI2JAK3FGF1SEPTIN6FOXI1FOXL1INAMAP3K20FGF2SHCBP1LIFT25CDX4UHRF2SYKETS2ELK1TEX19NKX1-1CCINMROH2BYY1AP1TYK2ID2ZIC1TTLL7PPARGFGF16PIWIL3TRIM54CEMP1UNC45AFOXA1DLK1CBX2HES6TYMPFGRSEPTIN7SMAD2MORN2SH2D2AGORASP2MYBL1ZNF541GTSF1CADM1FGF20CFAP91FOXD4L3AKT1HMX2FOXB2ATRAIDNELL1ZCWPW1SRPK3AAMPKLRK1FOXE3ODF2FLT1ODF1SLCO4C1ATOH8TSPY1RIMS2NHSSPATA20HEMGNMEF2CELF5NOTCH2NLARXRGZIC2ETV6ASF1BTSPY10RNF114SLC26A8EGFL6WIPF3ZIC5HNF4GCRIPTORB1SPATA31A1TNFRSF12APARP11OSGIN1FOXD4L6RMDN3PMCHBNC1CAMK2GTNFAIP2INHBBZSCAN2ASZ1THSD7AADCYAP1R1PTPN6PRKCHRASAL1FGF5DLX2THRBEID2OSTNCPNE5ETV3TXNDC2GNA12NKX3-2RBM38SPICKCTD19SOHLH1PLK5ANAPC2HUWE1ETV2SLC2A14CCDC87NRG1TCF12RBM11ECT2YIPF3RXRBSLC25A31NKX6-1RARANHSL3BTBD18NUDT21CCHCR1CATSPER1ODF4DLL1C14orf93FOXD4TMEFF2MAPK7FSTL1MDKEYA2NR1H4TFF1FGF21FHL1FGF9SFRP5NAA15C3orf62FOXD4L4SPAG8ECSCRSSH2PMP22DLL3JAK1GSK3BNKX2-4VIPAS39NUS1STAT3CALR3ETV1TSPY3NOTCH4SPATA31A3RBL2SRRM4MGPBEX1CIMAP1APPARDTLL1ARF6FOXD3DDX4CREBL2DHX36KRTDAPPPDPFSPMIP7AHDC1SMURF1ZHX1CPLX2FRKILDR2SMAD1ANXA13ZFP41ANKRD49RARRES2TCFL5BMP8ASPI1MUSKSPATA46RASGRP1ZEB1GPER1FGF19LRGUKRFNGMEF2DCENPFNHSL2GSK3ACDHR5PTPRUZNF431FLI1VSTM2ATCF23SPMIP6CREMHIP1NR2F6PPDPFLELK4DLX5PSMA8ETV3LZAP70ITGB1BP1COL13A1ARHGAP24SARM1DLX4VDRAMBRA1FGF17FOXK1FAM209ACYLC1EID2BNXNFOXB1PRRC2BPRM3CAV1HHEXMORC1MXRA8ERFTSNAXIP1NR2F1DDX41BMP8BTPPP2RNF151SMAD6TXNDC8EDAUNC45BRPL10LID1SFRP4CAMK1MOSPD1ELF4CCDC85BMSGN1ADIRFNKX2-1SMAD4FGF18PKDCCTESMINRARGSPATA31D4TBATASOX7SPATA9SUV39H1CAV2ZC3H12ARBM24FOXD4L1SEPTIN12DLX1IGSF10NKX2-3RPS3AHCKRXRACOL19A1GLRX2FOXI3SIM2PIWIL4SPATA24MAKJHYCAPRIN2TSNAXSLFN5TSPY4NDRG2FOXS1CHRDL1PPARAH1-6FOXC1ELF2NGEFBOLLSPOCD1M1APRAB29MMP19CHRDL2RUFY3CAMK2BUSP42EHFSOX15FGF4ARNTHSPG2MOSMOUNC13ACRXFGF3TBCBCLIC4MYO7BNKX6-2EYA3HERC4SPAG4FOXA2FOXL2CAV3TSSK3CAND1SOHLH2ANPEPTXNRD3GGNBP1ITSN2FOXC2GPSM1FOXJ3RBL1UGCGYES1NME8CCNYL1SFMBT1NDRG4FOXA3NKX2-5ERFLLRRC34SRD5A1DAZ2SERPINE2CDX2SRMSSMAD7ZFPM2BLKKIF2ASLC9C1MGAT4DSPATA19ZSCAN21DDX3XANKS4BFGF7FGF23CDX1DAZ1SQSTM1NPAP1SYAP1KAZALD1ABCB5CPNE9INHAETV4TSPY9ACSBG2FGF10BCL7BHES4DLX6INSCNKX3-1PEG10NDRG3ZNF3GLIS1PAX4RBM45