Insufficient scRNA-seq data for expression of TEX15 at tissue level.
Tissue | GTEx Coverage  | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
|---|---|---|---|---|---|---|
| uterus | 92% | 2240.78 | 156 / 170 | 17% | 0.54 | 77 / 459 |
| brain | 84% | 115.59 | 2213 / 2642 | 10% | 0.22 | 70 / 705 |
| spleen | 85% | 62.35 | 205 / 241 | 0% | 0 | 0 / 0 |
| ovary | 74% | 80.23 | 134 / 180 | 9% | 0.20 | 39 / 430 |
| bladder | 76% | 87.86 | 16 / 21 | 4% | 0.12 | 22 / 504 |
| stomach | 59% | 238.97 | 211 / 359 | 8% | 0.20 | 24 / 286 |
| esophagus | 28% | 31.37 | 399 / 1445 | 18% | 0.81 | 33 / 183 |
| tonsil | 0% | 0 | 0 / 0 | 31% | 1.20 | 14 / 45 |
| skin | 11% | 5.56 | 198 / 1809 | 20% | 0.75 | 94 / 472 |
| kidney | 2% | 0.66 | 2 / 89 | 23% | 1.13 | 207 / 901 |
| prostate | 12% | 7.03 | 29 / 245 | 1% | 0.02 | 5 / 502 |
| adrenal gland | 6% | 2.22 | 16 / 258 | 7% | 0.24 | 15 / 230 |
| lung | 3% | 1.10 | 19 / 578 | 9% | 0.24 | 101 / 1155 |
| peripheral blood | 12% | 17.28 | 109 / 929 | 0% | 0 | 0 / 0 |
| intestine | 5% | 2.48 | 45 / 966 | 3% | 0.11 | 14 / 527 |
| lymph node | 0% | 0 | 0 / 0 | 7% | 0.26 | 2 / 29 |
| breast | 3% | 2.07 | 14 / 459 | 3% | 0.14 | 38 / 1118 |
| liver | 2% | 0.77 | 4 / 226 | 3% | 0.10 | 13 / 406 |
| thymus | 3% | 1.55 | 19 / 653 | 0% | 0.00 | 1 / 605 |
| pancreas | 0% | 0 | 0 / 328 | 3% | 0.07 | 5 / 178 |
| heart | 3% | 0.87 | 24 / 861 | 0% | 0 | 0 / 0 |
| adipose | 1% | 0.41 | 14 / 1204 | 0% | 0 | 0 / 0 |
| blood vessel | 1% | 0.31 | 14 / 1335 | 0% | 0 | 0 / 0 |
| muscle | 1% | 0.68 | 8 / 803 | 0% | 0 | 0 / 0 |
| abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
| gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
| ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
| GO_0010526 | Biological process | retrotransposon silencing |
| GO_0010569 | Biological process | regulation of double-strand break repair via homologous recombination |
| GO_0006346 | Biological process | DNA methylation-dependent heterochromatin formation |
| GO_0006281 | Biological process | DNA repair |
| GO_0007130 | Biological process | synaptonemal complex assembly |
| GO_0007283 | Biological process | spermatogenesis |
| GO_0030154 | Biological process | cell differentiation |
| GO_0007140 | Biological process | male meiotic nuclear division |
| GO_0034587 | Biological process | piRNA processing |
| GO_0005737 | Cellular component | cytoplasm |
| GO_0005634 | Cellular component | nucleus |
| Gene name | TEX15 |
| Protein name | Testis-expressed protein 15 (Cancer/testis antigen 42) (CT42) Testis expressed 15 TEX15 protein Testis expressed 15, meiosis and synapsis associated |
| Synonyms | |
| Description | FUNCTION: Required during spermatogenesis for normal chromosome synapsis and meiotic recombination in germ cells. Necessary for formation of DMC1 and RAD51 foci on meiotic chromosomes, suggesting a specific role in DNA double-stranded break repair (By similarity). Essential executor of PIWIL4-piRNA pathway directed transposon DNA methylation and silencing in the male embryonic germ cells (By similarity). PIWIL4-piRNA binds to nascent transposon transcripts and interacts with TEX15, which may in turn recruit the epigenetic silencing machinery to the transposon loci (By similarity). Not required for piRNA biosynthesis (By similarity). . |
| Accessions | A5D8W7 ENST00000643185.2 B2RU27 A0A2R8Y358 Q9BXT5 ENST00000256246.5 ENST00000638951.1 A0A1W2PS94 |
