Insufficient scRNA-seq data for expression of DLX2 at single-cell level.
Insufficient scRNA-seq data for expression of DLX2 at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
skin | 84% | 99.14 | 1518 / 1809 | 32% | 5.17 | 150 / 472 |
brain | 69% | 96.64 | 1812 / 2642 | 32% | 2.03 | 223 / 705 |
thymus | 95% | 66.92 | 622 / 653 | 2% | 0.17 | 10 / 605 |
prostate | 16% | 4.09 | 40 / 245 | 75% | 4.10 | 376 / 502 |
adrenal gland | 18% | 10.32 | 47 / 258 | 53% | 5.67 | 121 / 230 |
breast | 31% | 29.55 | 141 / 459 | 36% | 4.30 | 406 / 1118 |
intestine | 59% | 20.50 | 569 / 966 | 6% | 0.33 | 29 / 527 |
esophagus | 18% | 4.56 | 267 / 1445 | 41% | 2.48 | 75 / 183 |
blood vessel | 30% | 18.06 | 405 / 1335 | 0% | 0 | 0 / 0 |
bladder | 19% | 3.86 | 4 / 21 | 7% | 0.34 | 35 / 504 |
stomach | 18% | 4.44 | 63 / 359 | 6% | 0.37 | 17 / 286 |
uterus | 4% | 0.66 | 6 / 170 | 18% | 2.74 | 84 / 459 |
tonsil | 0% | 0 | 0 / 0 | 16% | 0.30 | 7 / 45 |
lung | 1% | 0.16 | 4 / 578 | 15% | 1.18 | 171 / 1155 |
peripheral blood | 15% | 5.66 | 143 / 929 | 0% | 0 | 0 / 0 |
heart | 12% | 2.90 | 104 / 861 | 0% | 0 | 0 / 0 |
ovary | 3% | 0.49 | 5 / 180 | 9% | 1.26 | 39 / 430 |
adipose | 7% | 2.90 | 79 / 1204 | 0% | 0 | 0 / 0 |
liver | 2% | 0.38 | 4 / 226 | 4% | 0.16 | 16 / 406 |
kidney | 0% | 0 | 0 / 89 | 3% | 0.10 | 24 / 901 |
pancreas | 0% | 0.09 | 1 / 328 | 2% | 0.02 | 3 / 178 |
spleen | 2% | 0.75 | 4 / 241 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.02 | 1 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0042475 | Biological process | odontogenesis of dentin-containing tooth |
GO_0009790 | Biological process | embryo development |
GO_0048715 | Biological process | negative regulation of oligodendrocyte differentiation |
GO_0009954 | Biological process | proximal/distal pattern formation |
GO_0021766 | Biological process | hippocampus development |
GO_0007219 | Biological process | Notch signaling pathway |
GO_0021879 | Biological process | forebrain neuron differentiation |
GO_1902871 | Biological process | positive regulation of amacrine cell differentiation |
GO_0000122 | Biological process | negative regulation of transcription by RNA polymerase II |
GO_0021544 | Biological process | subpallium development |
GO_0021772 | Biological process | olfactory bulb development |
GO_0046533 | Biological process | negative regulation of photoreceptor cell differentiation |
GO_0045597 | Biological process | positive regulation of cell differentiation |
GO_0030154 | Biological process | cell differentiation |
GO_0048709 | Biological process | oligodendrocyte differentiation |
GO_0048701 | Biological process | embryonic cranial skeleton morphogenesis |
GO_0007420 | Biological process | brain development |
GO_0048755 | Biological process | branching morphogenesis of a nerve |
GO_0014016 | Biological process | neuroblast differentiation |
GO_0045746 | Biological process | negative regulation of Notch signaling pathway |
GO_0051216 | Biological process | cartilage development |
GO_0021893 | Biological process | cerebral cortex GABAergic interneuron fate commitment |
GO_0045944 | Biological process | positive regulation of transcription by RNA polymerase II |
GO_0000785 | Cellular component | chromatin |
GO_0005634 | Cellular component | nucleus |
GO_0000978 | Molecular function | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
GO_0001228 | Molecular function | DNA-binding transcription activator activity, RNA polymerase II-specific |
GO_0000981 | Molecular function | DNA-binding transcription factor activity, RNA polymerase II-specific |
GO_0003727 | Molecular function | single-stranded RNA binding |
GO_0003682 | Molecular function | chromatin binding |
GO_0000976 | Molecular function | transcription cis-regulatory region binding |
GO_1990837 | Molecular function | sequence-specific double-stranded DNA binding |
GO_0003700 | Molecular function | DNA-binding transcription factor activity |
GO_0005515 | Molecular function | protein binding |
Gene name | DLX2 |
Protein name | Distal-less homeobox 2 (cDNA FLJ75693, highly similar to Homo sapiens distal-less homeo box 2 (DLX2), mRNA) Distal-less homeobox 2 isoform A Homeobox protein DLX-2 |
Synonyms | hCG_16788 |
Description | FUNCTION: Acts as a transcriptional activator (By similarity). Activates transcription of CGA/alpha-GSU, via binding to the downstream activin regulatory element (DARE) in the gene promoter (By similarity). Plays a role in terminal differentiation of interneurons, such as amacrine and bipolar cells in the developing retina. Likely to play a regulatory role in the development of the ventral forebrain (By similarity). May play a role in craniofacial patterning and morphogenesis (By similarity). . |
Accessions | Q53QU7 ENST00000466293.2 [Q07687-2] ENST00000234198.9 [Q07687-1] Q07687 X5D7D8 |