ELK3 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0001525Biological processangiogenesis
GO_0006357Biological processregulation of transcription by RNA polymerase II
GO_0007165Biological processsignal transduction
GO_0000122Biological processnegative regulation of transcription by RNA polymerase II
GO_0042060Biological processwound healing
GO_0030154Biological processcell differentiation
GO_0045944Biological processpositive regulation of transcription by RNA polymerase II
GO_0005739Cellular componentmitochondrion
GO_0005654Cellular componentnucleoplasm
GO_0000785Cellular componentchromatin
GO_0005634Cellular componentnucleus
GO_0000978Molecular functionRNA polymerase II cis-regulatory region sequence-specific DNA binding
GO_0001228Molecular functionDNA-binding transcription activator activity, RNA polymerase II-specific
GO_0001227Molecular functionDNA-binding transcription repressor activity, RNA polymerase II-specific
GO_0000981Molecular functionDNA-binding transcription factor activity, RNA polymerase II-specific
GO_1990837Molecular functionsequence-specific double-stranded DNA binding
GO_0003700Molecular functionDNA-binding transcription factor activity
GO_0032422Molecular functionpurine-rich negative regulatory element binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameELK3
Protein nameETS transcription factor ELK3
ELK3, ETS-domain protein (SRF accessory protein 2), isoform CRA_b (ETS transcription factor ELK3)
ETS domain-containing protein Elk-3 (ETS-related protein ERP) (ETS-related protein NET) (Serum response factor accessory protein 2) (SAP-2) (SRF accessory protein 2)
SynonymsSAP2
NET
hCG_32371
DescriptionFUNCTION: May be a negative regulator of transcription, but can activate transcription when coexpressed with Ras, Src or Mos. Forms a ternary complex with the serum response factor and the ETS and SRF motifs of the Fos serum response element.

AccessionsF8VUJ0
ENST00000228741.8
F8VZQ0
P41970
ENST00000549985.1
ENST00000552142.5
ENST00000547249.1
H0YIH6
G3V1Z7
ENST00000547860.1