plasma cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
TNFRSF172251% ± 19%05
FCRL51841% ± 14%07
MEI11338% ± 14%03
IGLL51361% ± 26%07
SPAG41230% ± 12%02
TNFRSF13B1234% ± 13%04
MANEA927% ± 6%00
JSRP1925% ± 7%01
CD79A2463% ± 20%113
POU2AF12252% ± 18%112
CD272158% ± 20%130
ZBP11439% ± 21%111
FAM30A1123% ± 5%16
DERL32770% ± 21%27
SLAMF71937% ± 12%218
IRF41827% ± 10%29
TXNDC51449% ± 25%24
TP53INP11434% ± 13%211
CD79B1340% ± 15%213
MZB13281% ± 21%315
NCF11644% ± 19%336
SDC11434% ± 12%320
SYVN11330% ± 13%311
RAB301331% ± 13%316
RGS11640% ± 13%346
HSH2D1336% ± 13%321
TOR3A1230% ± 14%313
PIM22649% ± 19%436
TENT5C2155% ± 15%428
CYTIP2342% ± 16%457

III. Associated gene sets

GO_0030970Biological processretrograde protein transport, ER to cytosol
GO_0034620Biological processcellular response to unfolded protein
GO_1904871Biological processpositive regulation of protein localization to Cajal body
GO_0022417Biological processprotein maturation by protein folding
GO_0035278Biological processmiRNA-mediated gene silencing by inhibition of translation
GO_0097278Biological processcomplement-dependent cytotoxicity
GO_0000387Biological processspliceosomal snRNP assembly
GO_1904874Biological processpositive regulation of telomerase RNA localization to Cajal body
GO_0060545Biological processpositive regulation of necroptotic process
GO_0002260Biological processlymphocyte homeostasis
GO_0006613Biological processcotranslational protein targeting to membrane
GO_0042776Biological processproton motive force-driven mitochondrial ATP synthesis
GO_0051223Biological processregulation of protein transport
GO_1903241Biological processU2-type prespliceosome assembly
GO_0071569Biological processprotein ufmylation
GO_0001711Biological processendodermal cell fate commitment
GO_0002314Biological processgerminal center B cell differentiation
GO_0006620Biological processpost-translational protein targeting to endoplasmic reticulum membrane
GO_0036498Biological processIRE1-mediated unfolded protein response
GO_0043405Biological processregulation of MAP kinase activity
GO_0002502Biological processpeptide antigen assembly with MHC class I protein complex
GO_0001788Biological processantibody-dependent cellular cytotoxicity
GO_0044571Biological process[2Fe-2S] cluster assembly
GO_0160063Biological processmulti-pass transmembrane protein insertion into ER membrane
GO_0032368Biological processregulation of lipid transport
GO_0000245Biological processspliceosomal complex assembly
GO_0060267Biological processpositive regulation of respiratory burst
GO_0046626Biological processregulation of insulin receptor signaling pathway
GO_0006617Biological processSRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO_0006614Biological processSRP-dependent cotranslational protein targeting to membrane

IV. Literature review

[source]
Cell type nameplasma cell
Synonymsplasma B cell
plasma B-cell
plasmacyte
plasmocyte
DescriptionA terminally differentiated, post-mitotic, antibody secreting cell of the B cell lineage with the phenotype CD138-positive, surface immunonoglobulin-negative, and MHC Class II-negative. Plasma cells are oval or round with extensive rough endoplasmic reticulum, a well-developed Golgi apparatus, and a round nucleus having a characteristic cartwheel heterochromatin pattern and are devoted to producing large amounts of immunoglobulin.
ParentCL_0000946