SRP-dependent cotranslational protein targeting to membrane

I. Literature review

[source]
NameSRP-dependent cotranslational protein targeting to membrane
IDGO_0006614
collection_id

Biological process

Exact synonym

SRP-dependent cotranslational membrane targeting, SRP-dependent cotranslational protein-membrane targeting

Description

The targeting of proteins to a membrane that occurs during translation and is dependent upon two key components, the signal-recognition particle (SRP) and the SRP receptor. SRP is a cytosolic particle that transiently binds to the endoplasmic reticulum (ER) signal sequence in a nascent protein, to the large ribosomal unit, and to the SRP receptor in the ER membrane.

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