SRP14 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
B cell	47 studies	68% ± 20%	Explore
endothelial cell	46 studies	68% ± 26%	Explore
macrophage	41 studies	68% ± 23%	Explore
natural killer cell	41 studies	73% ± 17%	Explore
fibroblast	39 studies	76% ± 22%	Explore
CD8-positive, alpha-beta T cell	37 studies	70% ± 20%	Explore
T cell	36 studies	67% ± 21%	Explore
pericyte	35 studies	75% ± 24%	Explore
CD4-positive, alpha-beta T cell	33 studies	71% ± 19%	Explore
conventional dendritic cell	29 studies	83% ± 9%	Explore
smooth muscle cell	28 studies	76% ± 25%	Explore
plasmacytoid dendritic cell	27 studies	88% ± 12%	Explore
regulatory T cell	27 studies	78% ± 15%	Explore
dendritic cell	26 studies	73% ± 21%	Explore
classical monocyte	26 studies	70% ± 16%	Explore
non-classical monocyte	24 studies	78% ± 14%	Explore
epithelial cell	24 studies	76% ± 22%	Explore
mast cell	23 studies	66% ± 22%	Explore
plasma cell	23 studies	64% ± 20%	Explore
monocyte	22 studies	66% ± 19%	Explore
endothelial cell of lymphatic vessel	22 studies	80% ± 19%	Explore
mature NK T cell	22 studies	67% ± 20%	Explore
basal cell	21 studies	77% ± 21%	Explore
memory B cell	20 studies	74% ± 12%	Explore
naive B cell	20 studies	65% ± 18%	Explore
gamma-delta T cell	19 studies	74% ± 16%	Explore
connective tissue cell	19 studies	79% ± 17%	Explore
ciliated cell	18 studies	80% ± 19%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	18 studies	66% ± 19%	Explore
mucosal invariant T cell	16 studies	66% ± 18%	Explore
endothelial cell of artery	16 studies	76% ± 24%	Explore
capillary endothelial cell	16 studies	71% ± 16%	Explore
CD16-positive, CD56-dim natural killer cell, human	15 studies	73% ± 15%	Explore
myofibroblast cell	15 studies	82% ± 20%	Explore
CD16-negative, CD56-bright natural killer cell, human	14 studies	70% ± 20%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	14 studies	76% ± 15%	Explore
astrocyte	14 studies	41% ± 21%	Explore
vein endothelial cell	14 studies	72% ± 23%	Explore
endothelial cell of vascular tree	13 studies	78% ± 25%	Explore
myeloid cell	13 studies	73% ± 18%	Explore
effector memory CD8-positive, alpha-beta T cell	12 studies	66% ± 25%	Explore
innate lymphoid cell	12 studies	70% ± 17%	Explore
plasmablast	12 studies	76% ± 16%	Explore
CD4-positive, alpha-beta memory T cell	12 studies	72% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	12 studies	74% ± 18%	Explore
secretory cell	12 studies	84% ± 13%	Explore
type I pneumocyte	10 studies	67% ± 22%	Explore
T follicular helper cell	10 studies	74% ± 12%	Explore
neutrophil	10 studies	45% ± 18%	Explore
glutamatergic neuron	10 studies	32% ± 14%	Explore
progenitor cell	10 studies	84% ± 13%	Explore
abnormal cell	10 studies	75% ± 24%	Explore
goblet cell	10 studies	64% ± 21%	Explore
mesothelial cell	10 studies	82% ± 20%	Explore
erythrocyte	10 studies	54% ± 25%	Explore
type II pneumocyte	9 studies	70% ± 27%	Explore
club cell	9 studies	79% ± 21%	Explore
platelet	9 studies	53% ± 16%	Explore
leukocyte	9 studies	74% ± 19%	Explore
oligodendrocyte	8 studies	33% ± 14%	Explore
neuron	8 studies	69% ± 22%	Explore
IgG plasma cell	8 studies	47% ± 17%	Explore
microglial cell	8 studies	62% ± 23%	Explore
hematopoietic stem cell	8 studies	79% ± 23%	Explore
brush cell	8 studies	65% ± 26%	Explore
ionocyte	7 studies	83% ± 15%	Explore
respiratory goblet cell	7 studies	73% ± 18%	Explore
effector CD8-positive, alpha-beta T cell	7 studies	83% ± 12%	Explore
mononuclear phagocyte	7 studies	64% ± 24%	Explore
epithelial cell of proximal tubule	7 studies	73% ± 16%	Explore
enterocyte	7 studies	68% ± 14%	Explore
IgA plasma cell	7 studies	46% ± 17%	Explore
retinal rod cell	7 studies	59% ± 25%	Explore
precursor B cell	7 studies	76% ± 22%	Explore
immature B cell	7 studies	69% ± 26%	Explore
oligodendrocyte precursor cell	7 studies	43% ± 29%	Explore
alveolar macrophage	6 studies	73% ± 25%	Explore
effector CD4-positive, alpha-beta T cell	6 studies	83% ± 14%	Explore
kidney loop of Henle epithelial cell	6 studies	82% ± 15%	Explore
renal alpha-intercalated cell	6 studies	93% ± 3%	Explore
enteroendocrine cell	6 studies	76% ± 25%	Explore
erythroblast	6 studies	62% ± 25%	Explore
transit amplifying cell	6 studies	59% ± 29%	Explore
amacrine cell	6 studies	61% ± 24%	Explore
retinal ganglion cell	6 studies	71% ± 30%	Explore
retinal cone cell	6 studies	68% ± 30%	Explore
intermediate monocyte	6 studies	71% ± 27%	Explore
effector memory CD4-positive, alpha-beta T cell	6 studies	83% ± 11%	Explore
GABAergic neuron	6 studies	37% ± 10%	Explore
CD4-positive helper T cell	5 studies	63% ± 16%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	5 studies	69% ± 14%	Explore
hematopoietic precursor cell	5 studies	75% ± 20%	Explore
exhausted T cell	5 studies	85% ± 8%	Explore
kidney distal convoluted tubule epithelial cell	5 studies	93% ± 4%	Explore
megakaryocyte	5 studies	80% ± 15%	Explore
intestinal crypt stem cell	5 studies	69% ± 26%	Explore
OFF-bipolar cell	5 studies	56% ± 31%	Explore
ON-bipolar cell	5 studies	60% ± 31%	Explore
pro-B cell	5 studies	75% ± 20%	Explore
neuroendocrine cell	5 studies	90% ± 19%	Explore
glial cell	5 studies	66% ± 17%	Explore
T-helper 17 cell	5 studies	79% ± 14%	Explore
group 3 innate lymphoid cell	5 studies	80% ± 8%	Explore
double negative thymocyte	5 studies	87% ± 6%	Explore
granulocyte	5 studies	78% ± 17%	Explore
melanocyte	5 studies	67% ± 27%	Explore
interneuron	5 studies	49% ± 24%	Explore
CD4-positive, alpha-beta cytotoxic T cell	4 studies	65% ± 29%	Explore
central memory CD8-positive, alpha-beta T cell	4 studies	70% ± 17%	Explore
deuterosomal cell	4 studies	71% ± 18%	Explore
duct epithelial cell	4 studies	88% ± 3%	Explore
precursor cell	4 studies	70% ± 31%	Explore
pancreatic A cell	4 studies	92% ± 6%	Explore
type B pancreatic cell	4 studies	90% ± 8%	Explore
glomerular endothelial cell	4 studies	74% ± 13%	Explore
kidney connecting tubule epithelial cell	4 studies	88% ± 7%	Explore
podocyte	4 studies	89% ± 8%	Explore
retinal bipolar neuron	4 studies	67% ± 31%	Explore
lymphocyte	4 studies	90% ± 5%	Explore
retina horizontal cell	4 studies	72% ± 20%	Explore
retinal pigment epithelial cell	4 studies	55% ± 28%	Explore
adventitial cell	4 studies	76% ± 14%	Explore
mucus secreting cell	4 studies	73% ± 20%	Explore
Mueller cell	4 studies	71% ± 26%	Explore
acinar cell	4 studies	66% ± 17%	Explore
muscle cell	4 studies	49% ± 20%	Explore
germinal center B cell	4 studies	76% ± 13%	Explore
luminal hormone-sensing cell of mammary gland	4 studies	92% ± 7%	Explore
luminal cell of prostate epithelium	4 studies	68% ± 29%	Explore
hepatocyte	4 studies	57% ± 29%	Explore
T-helper 1 cell	4 studies	83% ± 10%	Explore
squamous epithelial cell	3 studies	64% ± 20%	Explore
pancreatic D cell	3 studies	93% ± 7%	Explore
monocyte-derived dendritic cell	3 studies	86% ± 12%	Explore
renal beta-intercalated cell	3 studies	96% ± 2%	Explore
neural crest cell	3 studies	90% ± 9%	Explore
GABAergic amacrine cell	3 studies	58% ± 17%	Explore
glycinergic amacrine cell	3 studies	52% ± 17%	Explore
renal principal cell	3 studies	87% ± 6%	Explore
thymocyte	3 studies	69% ± 22%	Explore
extravillous trophoblast	3 studies	94% ± 3%	Explore
placental villous trophoblast	3 studies	94% ± 6%	Explore
Schwann cell	3 studies	64% ± 33%	Explore
serous secreting cell	3 studies	69% ± 3%	Explore
tissue-resident macrophage	3 studies	56% ± 27%	Explore
intraepithelial lymphocyte	3 studies	79% ± 9%	Explore
rod bipolar cell	3 studies	73% ± 22%	Explore
cardiac muscle cell	3 studies	35% ± 13%	Explore
myoepithelial cell	3 studies	85% ± 5%	Explore
inflammatory macrophage	3 studies	58% ± 15%	Explore
IgM plasma cell	3 studies	67% ± 12%	Explore
pancreatic ductal cell	3 studies	94% ± 3%	Explore
megakaryocyte-erythroid progenitor cell	3 studies	88% ± 11%	Explore
keratinocyte	3 studies	78% ± 5%	Explore
central memory CD4-positive, alpha-beta T cell	3 studies	84% ± 2%	Explore
double-positive, alpha-beta thymocyte	3 studies	90% ± 5%	Explore
progenitor cell of mammary luminal epithelium	3 studies	88% ± 2%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
peripheral blood	20 studies	74% ± 13%	Explore
lung	18 studies	75% ± 14%	Explore
brain	17 studies	36% ± 17%	Explore
intestine	13 studies	64% ± 23%	Explore
eye	10 studies	63% ± 24%	Explore
kidney	9 studies	73% ± 16%	Explore
liver	7 studies	60% ± 23%	Explore
bone marrow	6 studies	55% ± 18%	Explore
lymph node	6 studies	75% ± 12%	Explore
pancreas	5 studies	80% ± 19%	Explore
uterus	5 studies	82% ± 19%	Explore
placenta	4 studies	81% ± 19%	Explore
heart	4 studies	34% ± 17%	Explore
prostate	4 studies	73% ± 21%	Explore
breast	4 studies	84% ± 5%	Explore
adipose	3 studies	37% ± 23%	Explore
adrenal gland	3 studies	65% ± 9%	Explore
esophagus	3 studies	72% ± 21%	Explore
skin	3 studies	69% ± 14%	Explore
thymus	3 studies	81% ± 21%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
adrenal gland	100%	12013.03	258 / 258	100%	443.04	230 / 230
brain	100%	12080.17	2642 / 2642	100%	397.08	705 / 705
esophagus	100%	10499.49	1445 / 1445	100%	264.69	183 / 183
ovary	100%	12484.84	180 / 180	100%	413.53	430 / 430
prostate	100%	11166.34	245 / 245	100%	456.26	502 / 502
stomach	100%	7940.67	359 / 359	100%	270.55	286 / 286
thymus	100%	12066.33	653 / 653	100%	499.91	605 / 605
uterus	100%	12918.17	170 / 170	100%	366.29	459 / 459
kidney	100%	12516.12	89 / 89	100%	316.79	900 / 901
intestine	100%	10210.19	966 / 966	100%	264.72	526 / 527
skin	100%	8739.99	1808 / 1809	100%	360.78	471 / 472
lung	100%	9293.20	576 / 578	100%	289.90	1155 / 1155
liver	100%	4944.15	225 / 226	100%	252.01	406 / 406
breast	100%	12431.92	459 / 459	100%	396.65	1113 / 1118
bladder	100%	10891.86	21 / 21	99%	306.09	501 / 504
pancreas	99%	4264.42	325 / 328	100%	302.69	178 / 178
adipose	100%	11961.89	1204 / 1204	0%	0	0 / 0
blood vessel	100%	12772.87	1335 / 1335	0%	0	0 / 0
lymph node	0%	0	0 / 0	100%	390.36	29 / 29
spleen	100%	8856.91	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	269.53	45 / 45
ureter	0%	0	0 / 0	100%	204.95	1 / 1
muscle	100%	8052.33	801 / 803	0%	0	0 / 0
heart	99%	9285.61	856 / 861	0%	0	0 / 0
eye	0%	0	0 / 0	99%	338.60	79 / 80
peripheral blood	91%	6037.37	844 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0045047	Biological process	protein targeting to ER
GO_0006614	Biological process	SRP-dependent cotranslational protein targeting to membrane
GO_0006613	Biological process	cotranslational protein targeting to membrane
GO_0005786	Cellular component	signal recognition particle, endoplasmic reticulum targeting
GO_0034774	Cellular component	secretory granule lumen
GO_1904813	Cellular component	ficolin-1-rich granule lumen
GO_0005829	Cellular component	cytosol
GO_0005576	Cellular component	extracellular region
GO_0005737	Cellular component	cytoplasm
GO_0005634	Cellular component	nucleus
GO_0030942	Molecular function	endoplasmic reticulum signal peptide binding
GO_0008312	Molecular function	7S RNA binding
GO_0005515	Molecular function	protein binding
GO_0003723	Molecular function	RNA binding

IV. Literature review

[source]

Gene name	SRP14
Protein name	Signal recognition particle 14 kDa protein (SRP14) (18 kDa Alu RNA-binding protein) Signal recognition particle 14 Signal recognition particle 14 kDa protein (SRP14)
Synonyms
Description	FUNCTION: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER) . SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP . The complex of SRP9 and SRP14 is required for SRP RNA binding . . FUNCTION: Component of the signal recognition particle (SRP) complex, a ribonucleoprotein complex that mediates the cotranslational targeting of secretory and membrane proteins to the endoplasmic reticulum (ER). SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. .
Accessions	H0YLA2 H0YLW0 ENST00000559081.1 ENST00000558720.5 ENST00000560773.5 ENST00000267884.11 P37108

SRP14 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review