T-helper 1 cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
CD40LG345% ± 17%010
CD6439% ± 11%024
TRAT1332% ± 10%020
CD5329% ± 9%020
ZAP70333% ± 12%027
GZMM330% ± 8%027
TNF343% ± 18%114
KLRB1452% ± 26%126
CD3G459% ± 8%129
GZMA341% ± 10%126
CD27324% ± 9%130
LCK469% ± 12%234
CD3D489% ± 3%234
SIT1331% ± 11%224
CD2484% ± 9%235
CD96344% ± 10%233
CD247353% ± 10%234
TNFRSF25321% ± 3%316
CD3E488% ± 10%337
GATA3338% ± 3%328
S1PR4321% ± 3%329
LAT346% ± 11%329
TRADD330% ± 10%329
SKAP1337% ± 9%335
DOK2341% ± 5%337
MYO1G333% ± 12%337
RASSF5330% ± 3%337
CD7359% ± 5%337
CCL5462% ± 15%433
PIM2335% ± 7%436

III. Associated gene sets

GO_0002925Biological processpositive regulation of humoral immune response mediated by circulating immunoglobulin
GO_2000010Biological processpositive regulation of protein localization to cell surface

IV. Literature review

[source]
Cell type nameT-helper 1 cell
SynonymsT helper cells type 1
T(H)-1 cell
Th1 CD4+ T cell
Th1 T cell
Th1 T lymphocyte
Th1 T-cell
Th1 T-lymphocyte
Th1 cell
helper T cell type 1
DescriptionA CD4-positive, alpha-beta T cell that has the phenotype T-bet-positive, CXCR3-positive, CCR6-negative, and is capable of producing interferon-gamma.
ParentCL_0000492