SIT1 report

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I. Expression across cell types

Cell ontologyData table

Name	Number of supported studies	Average coverage
CD8-positive, alpha-beta T cell	23 studies	33% ± 13%	Explore
CD4-positive, alpha-beta T cell	22 studies	28% ± 11%	Explore
regulatory T cell	19 studies	35% ± 15%	Explore
B cell	17 studies	25% ± 11%	Explore
T cell	16 studies	28% ± 10%	Explore
memory B cell	11 studies	24% ± 5%	Explore
plasmacytoid dendritic cell	10 studies	32% ± 13%	Explore
naive B cell	7 studies	26% ± 11%	Explore
T follicular helper cell	7 studies	21% ± 4%	Explore
CD4-positive, alpha-beta memory T cell	6 studies	38% ± 17%	Explore
CD8-positive, alpha-beta memory T cell	6 studies	38% ± 12%	Explore
naive thymus-derived CD4-positive, alpha-beta T cell	6 studies	22% ± 5%	Explore
exhausted T cell	5 studies	52% ± 13%	Explore
effector CD8-positive, alpha-beta T cell	5 studies	39% ± 12%	Explore
effector memory CD8-positive, alpha-beta T cell	5 studies	27% ± 11%	Explore
naive thymus-derived CD8-positive, alpha-beta T cell	5 studies	33% ± 15%	Explore
precursor B cell	4 studies	32% ± 17%	Explore
effector CD4-positive, alpha-beta T cell	4 studies	56% ± 15%	Explore
effector memory CD4-positive, alpha-beta T cell	4 studies	39% ± 20%	Explore
mucosal invariant T cell	4 studies	25% ± 5%	Explore
T-helper 17 cell	4 studies	26% ± 7%	Explore
immature B cell	3 studies	43% ± 13%	Explore
germinal center B cell	3 studies	36% ± 6%	Explore
T-helper 1 cell	3 studies	31% ± 11%	Explore
effector memory CD8-positive, alpha-beta T cell, terminally differentiated	3 studies	23% ± 5%	Explore

II. Expression across tissues

sc-RNAseq dataData table

Name	Number of supported studies	Average coverage
lymph node	3 studies	25% ± 1%	Explore

Bulk RNAseq dataData table

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
lung	98%	102.63	569 / 578	88%	9.28	1019 / 1155
stomach	83%	57.68	298 / 359	84%	10.33	239 / 286
breast	85%	49.20	390 / 459	70%	7.37	784 / 1118
intestine	63%	224.77	610 / 966	81%	7.87	425 / 527
thymus	78%	62.27	508 / 653	58%	38.24	349 / 605
uterus	58%	17.13	99 / 170	67%	5.94	307 / 459
prostate	74%	43.54	182 / 245	51%	2.65	254 / 502
kidney	52%	40.25	46 / 89	70%	7.72	632 / 901
bladder	52%	45.62	11 / 21	62%	7.58	314 / 504
skin	43%	13.06	781 / 1809	70%	13.61	329 / 472
esophagus	47%	25.07	676 / 1445	56%	3.48	103 / 183
lymph node	0%	0	0 / 0	100%	293.06	29 / 29
spleen	100%	1468.15	241 / 241	0%	0	0 / 0
peripheral blood	100%	1381.87	927 / 929	0%	0	0 / 0
adipose	93%	61.08	1122 / 1204	0%	0	0 / 0
tonsil	0%	0	0 / 0	91%	16.93	41 / 45
pancreas	19%	5.54	62 / 328	70%	7.90	125 / 178
liver	46%	13.81	104 / 226	39%	3.24	159 / 406
ovary	13%	5.08	23 / 180	65%	4.47	280 / 430
blood vessel	55%	28.30	731 / 1335	0%	0	0 / 0
adrenal gland	41%	12.65	105 / 258	12%	0.49	28 / 230
eye	0%	0	0 / 0	21%	2.21	17 / 80
heart	20%	6.20	171 / 861	0%	0	0 / 0
brain	5%	1.25	119 / 2642	13%	1.17	89 / 705
muscle	2%	0.51	14 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1