GO_0002250 | OmnibusX

adaptive immune response

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	ALCAM-CD6	CD166_HUMAN - CD6_HUMAN	Ligand-Receptor
2	BTLA-TNFRSF14	BTLA_HUMAN - TNR14_HUMAN	Ligand-Receptor	Signaling by Tumor necrosis factor
3	CD160-TNFRSF14	BY55_HUMAN - TNR14_HUMAN	Adhesion-Adhesion	Signaling by Tumor necrosis factor
4	CD274-PDCD1	PD1L1_HUMAN - PDCD1_HUMAN	Ligand-Receptor
5	CD86-CTLA4	CD86_HUMAN - CTLA4_HUMAN	Ligand-Receptor
6	FGL1-LAG3	FGL1_HUMAN - LAG3_HUMAN	Ligand-Receptor	Signaling by Fibroblast growth factor
7	LAIR1-LILRB4	LAIR1_HUMAN - LIRB4_HUMAN	Receptor-Receptor
8	MICB-HCST+KLRK1	MICB_HUMAN -	Ligand-Receptor
9	PDCD1LG2-PDCD1	PD1L2_HUMAN - PDCD1_HUMAN	Ligand-Receptor

II. Literature review

Name	adaptive immune response
ID	GO_0002250
collection_id	Biological process
Exact synonym	acquired immune response, immune memory response
Description	An immune response mediated by cells expressing specific receptors for antigens produced through a somatic diversification process, and allowing for an enhanced secondary response to subsequent exposures to the same antigen (immunological memory).
External URL
Genes	ighg3-iglc6_human TRBV4-2 TRBJ1-2 IGLV2-14 TRGV3 TRBV6-9 igha1-igkc_human TRBJ2-5 IGKV2D-28 igha1-iglc6_human TRBV6-1 IFNA6 TRBV10-1 SIT1 TRBV6-2 TRBV16 IGKV1D-39 IFNK TRAV18 LAMP3 ighm-igkc_human LILRB5 IGLV10-54 IGHG4 TRBJ1-4 JCHAIN TRGV10 IGKV1-37 TRBV7-4 IGLV3-9 ighg2-iglc3_human TRBV12-5 ighg4-iglc1_human IFNA8 IGLV3-12 VTCN1 HLA-DRA IGLV5-48 ighg2-iglc6_human TRAV24 IFNA2 LILRA6 TRGV4 TRAV10 CD274 TRGV11 TRBV17 IGLV3-21 IFNB1 CD244 IGHD1-1 ighm-iglc7_human TRAV3 TRBV9 TRAV13-2 TRBD1 TRBV11-1 IL17A AKIRIN2 TRBV12-4 LAIR1 IGLV1-44 CD3D HLA-DQA2 CX3CR1 CLEC4C CLEC4D IGLV6-57 ighg2-iglc7_human CD46 TAP1 TRAV34 IGLV2-33 IGLV1-47 TRAV8-1 IGKV1-27 IGKV1-39 TRAV27 IGLV2-23 ighd-iglc6_human IFNA14 TRBJ1-3 TRDD1 IGHG1 ighg3-iglc1_human TRBV14 IFNA10 cd8aa_human IGHA2 RAPGEF4 IFNE TRBV6-4 TRAV26-2 TNFRSF14 IGKV2D-40 PDIA3 TRAV12-3 JAK2 IGKV1D-13 TRAV9-1 CD7 RAP1GAP2 CLEC6A KLRD1 TRGJ1 MCOLN2 CD8B2 igha2-iglc2_human IGLV5-37 TRBV19 IGKC IFNA1 IGLV1-51 IL17F KLRC1 IGKV1-16 TRBV5-8 HLA-DPA1 ighg4-iglc6_human IGLV2-8 TRBV7-9 TEC IGLV3-32 TRAV17 IFNA4 tcr_gamma1_human FYN TRBV7-6 IGKV3-15 PDCD1 CD8B TRBV5-7 CD79A IGLC1 BTN3A1 IGHD TRBV11-2 LIME1 ighg1-iglc1_human ighe-iglc2_human JAK3 TRAV6 SIGLEC10 IGKV1D-12 ERAP1 CD1B TRBV6-3 HLA-C TNFRSF21 SYK ighe-iglc6_human IGLV1-40 CD209 TRAV8-6 LILRB4 TNFRSF13B TRPM4 KCNJ8 IGKV2-40 SIPA1 IGKV2-28 TRAV8-2 IGKV1D-16 LILRA1 RAPGEF3 PIK3CD ALCAM RAG1 BCL10 ICOSLG ARG2 IGKV1-8 TREM1 MPEG1 EIF2AK4 IGKJ1 IGLV3-10 TRAV36DV7 DCLRE1C KLRK1 TRBV7-3 ighg1-igkc_human TRAV4 TRBV13 IGKV3D-20 HLA-DPB1 HLA-DQB1 ERAP2 CLEC4M PAG1 HLA-DMA PTK2B CD1E TRAV9-2 TRGV1 ORAI1 IGLV4-69 IGKV2D-29 DBNL TRAV1-1 HMHB1 IGKV2-30 TRBV30 ighg3-iglc7_human IGKV1-9 ighd-iglc1_human PIK3CG CD84 TRBV5-6 TXK IGLC3 tcr_gamma2_human ighg2-iglc2_human tcr_beta2_human TRAV1-2 IGLV1-36 TRBV3-1 TRBV29-1 IGKV1D-37 SH2D1B OTUD7B BTLA IL4I1 TRBV5-3 MCOLN1 TRBV6-6 CTLA4 TRDV2 ighd-iglc7_human SLAMF1 TRGV8 BMX PDCD1LG2 TRBV4-3 IGLC7 IGKV2D-24 TRAV7 TRAV14DV4 TRAV19 IFNA21 LAT TRBV5-1 FGA igha1-iglc3_human TSC1 IGLV3-22 TRBJ1-6 FBXO38 TRBV6-8 IGKV2-24 FCAMR TRBV5-4 MARCHF8 TRGV9 TRGC1 LILRB1 IGKV1-5 TNFRSF11A IFNA5 TRBJ1-5 CD6 CD79B igha1-iglc7_human TRAV30 IGKV1-12 TRBJ1-1 ighd-iglc2_human GPR183 igha1-iglc2_human ighg4-iglc3_human ighm-iglc3_human ighg1-iglc3_human TRBJ2-2 IGKV1-13 ighe-iglc7_human TRAV29DV5 TRBJ2-6 IGLV4-60 CD3G HLA-DRB4 RIPK2 BTK IGLV3-27 TRAV38-2DV8 IGHA1 CD1C HLA-DQA1 HLA-E CRACR2A ighm-iglc2_human TRAJ31 FCRL4 CD3E IGLC6 RNF125 IGHV3OR16-9 ighd-igkc_human RNF19B IGLV8-61 TRBV7-8 IGLV3-16 TRAV12-1 TNFRSF17 IGKV3D-7 CSK IGKV4-1 TRAC EOMES igha2-iglc3_human CTSL ighe-iglc1_human TRBV25-1 TRAV40 IGKV1D-42 TRAV23DV6 LYN IGHM KLRC2 TRBV7-2 TRDV1 TRAV39 LAT2 IGKV1D-17 TRDJ1 HLA-DOA TRAV16 ighg2-iglc1_human ZAP70 IGKV2-29 ighg4-iglc7_human TRBJ2-7 IGKV6-21 TRBV6-5 TFE3 ighg1-iglc7_human IGLV3-25 IGKV5-2 TRGV5 IGLV3-19 IGKV2D-26 TRBV24-1 TRBV18 HLA-B IGLV11-55 igha2-iglc7_human NLRP10 TRBV6-7 TRAJ3 IGKV3-20 TRBV5-5 ADGRE1 CD1A TRAV8-3 TRBV4-1 IGLV3-1 igha2-igkc_human JAM3 TRAV8-4 IFNA17 CD247 ighm-iglc6_human IGHE IGHG3 TRGV2 TRDV3 CD86 SH2D1A IGKV1D-8 TRDC ITK IFNG TRBC1 ighe-igkc_human TRAJ42 CD160 ARG1 BTNL8 IGLV4-3 IGLV7-46 TRAV13-1 HLA-DRB5 TRBV12-3 IGKV1-33 LILRB3 igha2-iglc6_human OTUB1 IGKV3D-15 TRAV25 ighg2-igkc_human CTSH RAP1GAP igha2-iglc1_human igha1-iglc1_human TRBJ2-1 TRGC2 TRAV35 TRAV20 ighe-iglc3_human CD4 PRKCB ighg4-iglc2_human TRAV26-1 TRBV10-2 TRBV23-1 CLEC4A ZNF683 TRBV2 SKAP1 TRBV20-1 TRAV38-1 IFNA16 TRBV11-3 IGLJ1 TRBV7-1 PRDM1 C17orf99 IL2 IFNA7 IGHG2 TRAV5 IGKV1-17 TRAT1 HAVCR2 HLA-DOB IGKV3D-11 IGLV2-18 ighg1-iglc6_human PRKD2 ighg3-iglc3_human TARM1 MICB LAX1 IGHJ1 NOD2 IGKV2D-30 TRAV22 ANXA1 IFNW1 IGLV5-39 LILRA3 TRBV28 IGKV1D-33 ighg1-iglc2_human cd8ab_human TRBJ2-3 TRBC2 HLA-DQB2 CAMK4 THEMIS IGLV7-43 TRBV7-7 ighg3-igkc_human HLA-DRB3 CLEC10A LAG3 CTNNBL1 IGKV1-6 IGKV3-7 TFEB IGLV2-11 IGLV9-49 ighd-iglc3_human ighg3-iglc2_human CD8A LILRB2 ighg4-igkc_human IGLV1-50 CTSS ighm-iglc1_human SLAMF7 PRR7 TRBV27 TRAV12-2 TNFRSF13C IGKV1D-43 TNFSF18 TRAV2 tcr_beta1_human FGL1 IGLV5-45 HLA-DMB IGLV5-52 IGKV3-11 TRBV10-3 TRAV41 FGB IGKV6D-21 TRAV21 IGKV6D-41 TRBJ2-4