ADGRE1 report

I. Expression across cell types

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of ADGRE1 at tissue level.

III. Associated gene sets

GO_0002250Biological processadaptive immune response
GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007155Biological processcell adhesion
GO_0007166Biological processcell surface receptor signaling pathway
GO_0009897Cellular componentexternal side of plasma membrane
GO_0005886Cellular componentplasma membrane
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0005509Molecular functioncalcium ion binding

IV. Literature review

[source]
Gene nameADGRE1
Protein nameAdhesion G protein-coupled receptor E1
Adhesion G protein-coupled receptor E1 (EGF-like module receptor 1) (EGF-like module-containing mucin-like hormone receptor-like 1) (EMR1 hormone receptor)
SynonymsEMR1
TM7LN3
DescriptionFUNCTION: Orphan receptor involved in cell adhesion and probably in cell-cell interactions specifically involving cells of the immune system. May play a role in regulatory T-cells (Treg) development. .

AccessionsM0R2G7
Q14246
ENST00000381407.9 [Q14246-5]
ENST00000312053.9 [Q14246-1]
ENST00000250572.12 [Q14246-2]
ENST00000450315.7 [Q14246-4]
ENST00000381404.8 [Q14246-3]
ENST00000595026.1