GO_0004930 | OmnibusX

G protein-coupled receptor activity

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	LPAR1-ADGRE5	LPAR1_HUMAN - CD97_HUMAN	Receptor-Receptor	Signaling by Lysophosphatidic acid receptor
2	LPAR2-ADGRE5	LPAR2_HUMAN - CD97_HUMAN	Receptor-Receptor	Signaling by Lysophosphatidic acid receptor
3	LPAR3-ADGRE5	LPAR3_HUMAN - CD97_HUMAN	Receptor-Receptor	Signaling by Lysophosphatidic acid receptor
4	NPY-NPY4R	NPY_HUMAN - NPY4R_HUMAN	Ligand-Receptor	Signaling by Pro-neuregulin
5	NPY-PRLHR	NPY_HUMAN - PRLHR_HUMAN	Ligand-Receptor	Signaling by Pro-neuregulin

II. Literature review

Name	G protein-coupled receptor activity
ID	GO_0004930
collection_id	Molecular function
Alternative ID	GO:0001622, GO:0001623, GO:0001624, GO:0001625, GO:0016526
Exact synonym	G protein coupled receptor activity, G protein linked receptor activity, G-protein coupled receptor activity, G-protein linked receptor activity, GPCR activity, ligand-dependent GPCR activity, receptor activity, G-protein coupled
Description	Combining with an extracellular signal and transmitting the signal across the membrane by activating an associated G-protein; promotes the exchange of GDP for GTP on the alpha subunit of a heterotrimeric G-protein complex.
External URL
Genes	OR51B6 SLC39A9 OR4A5 GPRC5D OR8U1 OR6K6 OR52J3 OR1J2 GRM3 GPRC6A OR52L2P OR6C76 OR2B2 OR4C46 OR14J1 PTAFR GRM8 OR8G2P OR13G1 OR6C70 GPR55 OR11H1 OR6B2 OR13J1 OR6K2 OR6C3 MRGPRX1 OR8K3 OR7G1 OR5B12 OR6J1 ADGRG2 OR52L1 OR1D4 OR2W1 ADGRL1 OR52K1 C5AR1 OR4E2 ADGRB3 OR51B4 OR2B6 TAS2R36 GPR83 TAS2R4 ADGRF3 OR51C1P OR4F6 S1PR2 OR8B12 OR2A2 OR2AG1 OR51I2 OR6X1 OR10G9 SUCNR1 OR2I1P S1PR5 OR51B2 GPR142 OR5M3 ADGRG4 ADORA2B OR51B5 OR5A2 GPR119 OR2J2 UTS2R OR2L13 OR4F17 OR51F2 OR52B2 OR11H2 OR8B2 GPR33 OR5AU1 GPR52 OR5H15 OR9I1 CXCR1 OR52B6 OR7G2 P2RY8 OR56A3 OR2B3 OR7G3 OR8U3 CCR7 TAS2R60 OR52E2 OR56B4 OR2V2 OR1G1 OR2AP1 CX3CR1 OR14L1 GPR162 OR5M11 OR6Y1 OR6N2 OR1E3 OR51G1 OR4M2B OR9Q2 OR10W1 TAS2R31 OR52P1 GPR75 OR2T29 OR5H1 OR10A4 OR6C6 OR7C2 GPR65 OR6Q1 OR5D18 OR52K2 OR2B8P TAS2R19 LANCL1 GPR61 MAS1L OR6B1 LOC112268384 TAS2R39 OR51E1 OR8S1 OR10K2 RRH OR7D4 OR5AN1 OR4K13 OR2T6 GPR101 GPR12 ADGRG7 OR6C68 NPY TAS2R43 OR4F15 GPR25 OR4C6 OR4D6 OR2J1 OR2A25 OR5M8 OR52A1 QRFPR TAS2R42 GPR22 OR11L1 TAS2R1 HCRTR1 GHRHR OR8I2 ADGRG6 OR4D9 OR6F1 OR52I1 OR9K2 OR7A10 OR13F1 OR5AC1 OR10C1 OR5M9 FFAR2 MRGPRX3 OR9G9 OR2L8 OR12D3 OR4N4C OR10A7 OR10J1 CXCR4 OR6B3 GRM5 OR5M1 OR9A2 S1PR4 TAS1R2 TAS2R30 CXCR5 OR6P1 TM2D1 OR2M3 OR10G3 OR9A1P ADGRE4P OR5B17 MCHR1 TAS2R14 NPFFR2 TAS2R33 CMKLR1 GPR157 OR5H2 OR11H6 GPR150 OR13C8 P2RY6 MRGPRD OR5H8 OR5T3 GPR37L1 TAS2R45 OR1F1 OR5F1 OR10G4 OR5D14 HCAR1 OR10A5 GPR3 OR2AJ1 OR10H4 OR2S2 CNR1 GPR176 OR6V1 OR10Z1 TAS2R16 NTSR2 OR1D5 OR52E5 OR56A4 OR2AE1 OR1A1 PTGDR2 RXFP1 GPR63 OR2T5 SSTR3 OR4Q2 LPAR5 OR4K17 F2R OR4S1 OR10H3 OR10G2 RHO OR51I1 OR8D4 TAS2R20 FZD2 OR5G3 OR52A5 OR2G3 GPR19 OR5L1 OR2D3 FZD6 OR4C45 GRM4 OR1S2 OR51V1 OR10D3 OR56A5 OR5P3 S1PR3 GPR37 OR10R2 DRD1 OR9A4 LGR6 TAS2R13 FZD10 OR12D2 GPR27 PROKR1 OR51Q1 OR2M2 OR52D1 TAS1R1 OR13H1 OR10H1 OR52E6 TAS2R41 OR8U9 OR5D13 OR6C75 FPR2 OR7A2P OR8H1 OR7A5 OR5B3 OR6N1 ADGRB2 OR52N4 OR2H2 gpr88-gi1_human NPBWR2 PROKR2 OR5H14 OR2B11 OR2G2 OR13C2 OR14I1 TAS2R7 TAS1R3 OPN3 GPR31 OR1L8 DRD5 OR1N1 OR5M10 OR4N2 OR4K14 OR2AK2 GPR143 OR5K2 OR6C74 OR8D2 OR51D1 OR2T1 OR5AK3P OR6S1 OR51S1 ADGRA2 TPRA1 ADGRL4 OR2W6P OR4N5 OR1S1 TAS2R5 OR5K1 FFAR1 OR2T33 GPR17 OR5V1 OR4C3 OR8K1 TAS2R50 OR1J4 PGR CELSR2 OR5D3P OR2F2 OR4M2 OR52E1 OR4D10 MRGPRG A0A0G2JNH3 OR8B3 OR2AG2 LGR4 GPR171 OR1A2 OR10G8 OR2M4 OR52W1 GPRC5A OR10V1 OR5AL1 OR14A2 OR1L1 MRGPRX4 OR2T35 OR52N2 OR11H7 FFAR4 OR10J6P OR8A1 ADGRE5 GPR183 AR OR5B2 OR51L1 OR13C9 OR13C6P OR11A1 GPR15 OR5C1 NPBWR1 OR13D1 F2RL3 GPR4 OR14C36 LGR5 GPR42 OR2G6 OR4D11 MTNR1B OR2T34 OR4F4 OR4A47 OR5T1 RXFP3 OR4A15 OR51A7 GPR18 ADGRF5 OR2M5 FZD9 OR6C1 OR8D1 MRGPRE GPR173 GPR152 OR6A2 OR4K3 OR5AC2 FZD5 OR1N2 GPR50 GPR151 OR2A7 OR2C1 OR3A1 OR1L6 OPRL1 OR9G1 ADGRD1 TAS2R10 OR6T1 TAAR5 OR1I1 OR51A2 OR2A14 TAS2R3 OR4F16 OR9G4 GPR68 GPR149 GPR182 OR2W3 GRM1 ADGRA3 ADGRF2P ADGRD2 OR3A2 OR1L3 GPER1 GPR160 OR4C13 GPR62 OR5BS1P OR2V1 OR2M7 OR7D2 OR2A42 OR4N4 OR4C12 OR2T8 OR4S2 OR5B21 OR2A12 OR1E2 OR1K1 OR10A2 ADGRF1 OR4D5 OR51E2 OR56B2P OR5P2 OR8B4 C5AR2 LPAR2 OR52E8 MRGPRF OR2AT4 OR4F5 FZD1 ADGRA1 OR14A16 OR11H4 OR2Y1 OR1F2P OR10A3 OR2K2 OR52M1 OR10H2 CALCRL DRD2 APLNR OR1D2 GHSR OR4F21 TAAR6 OR8H3 SMO OR2D2 OR10G7 GLP2R OR5W2 OR52Z1P VIPR2 GPR21 OR4M1 OR5AR1 OR4A8 OR14K1 OR8J1 NMUR1 OR1B1 ADGRE3 OR4E1 OR4X1 OR10AD1 GPR26 OR13C5 ADGRE1 OR52B4 OR5K3 OR4D1 HTR1E GPR161 OR51T1 DRD3 PRLHR TAAR9 P2RY10 TAS2R9 OR12D1 F2RL1 OR4B1 OR5J2 GPR45 TAS2R46 OR3A3 CXCR6 GPR85 OR4L1 OR2H1 OR2T27 NMUR2 OR4Q3 OR6C4 OR2A1 OR10T2 OR52N5 OR10AG1 OR1P1 OR5AK2 TAAR3P OR51F1 OR10AC1 ADGRG1 OR4K5 OR6C2 OR5L2 ADGRB1 CELSR1 NTSR1 CMKLR2 GPR179 OR4K15 OR11G2 OR1M1 OR4X2 GPR141 OR10J4 OR52E4 OR7A17 GPR153 GPRC5B OR4P4 TAAR2 OR2Z1 OR13C3 LPAR1 OR4C11 OR51M1 OR10H5 OR1F12P OR56B1 CELSR3 OR5AS1 OR1Q1 OR10X1 OR10J3 OR9Q1 CCR10 OR5D16 GPR148 OR6K3 OR2L3 OR6M1 OR10Q1 GRM2 OR4A16 TAAR8 OR2T2 TAS2R40 TAS2R8 OR8G3P CASR OR2T11 OR2W5P OR56A1 F2RL2 OR10S1 RGR OR8K5 GPR135 GPR6 OR4C15 OR8J3 OR1C1 OR2A5 GPR32 GPR78 OR2T10 OR4D2 OR2C3 FFAR3 OR10J5 OR10A6 CXCR2 OR8G5 OR5H6 OR2J3 S1PR1 FZD4 ADGRG3 ADGRG5 GPR146 GPR82 HCAR3 MRGPRX2 OR52A4P OR4A4P OR2F1 GPR35 OR11H12 ACKR1 OR5A1 OXER1 GRM6 OR7C1 FZD3 OR7E24 OR4K1 LPAR3 OR52I2 OR51A4 OR2L2 OR5T2 OXGR1 ADGRL3 FZD7 OR13C4 GPRC5C OR5I1 GPR132 FZD8 OR1E1 OR4C16 ADGRV1 OR8B8 MTNR1A ADGRE2 OR1L4 OR3A4P OR2T3 OR6C65 OR2T7 OR8H2 OR1J1 OR8U8 OR4C5 OR51H1 GPR34 OR52H1 OR13C7 GPR39 MAS1 TAS2R38 OR4K2 C3AR1 OR2A4 OR51G2 OR8J2 OR10K1 MC2R OPRM1 OR5K4 FPR1 OR52N1 NPY4R ADGRF4 GPR174 ADGRL2 GPR20 OR2L5 OR51J1 OR8G1 OR13A1 NPFFR1 OR10G6 OR52R1 OR10D4P TAAR1 OR2T4 OR2T12 OR10P1 OR5AP2