ADGRL1 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0007186Biological processG protein-coupled receptor signaling pathway
GO_0007189Biological processadenylate cyclase-activating G protein-coupled receptor signaling pathway
GO_0007157Biological processheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO_0007166Biological processcell surface receptor signaling pathway
GO_0030424Cellular componentaxon
GO_0045202Cellular componentsynapse
GO_0042734Cellular componentpresynaptic membrane
GO_0005886Cellular componentplasma membrane
GO_0030426Cellular componentgrowth cone
GO_0043005Cellular componentneuron projection
GO_0016020Cellular componentmembrane
GO_0016524Molecular functionlatrotoxin receptor activity
GO_0050839Molecular functioncell adhesion molecule binding
GO_0004930Molecular functionG protein-coupled receptor activity
GO_0030246Molecular functioncarbohydrate binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameADGRL1
Protein nameAdhesion G protein-coupled receptor L1
LPHN1 protein
Adhesion G protein-coupled receptor L1 (Calcium-independent alpha-latrotoxin receptor 1) (CIRL-1) (Latrophilin-1) (Lectomedin-2)
SynonymsLEC2
KIAA0821
LPHN1
DescriptionFUNCTION: Calcium-independent receptor of high affinity for alpha-latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells . Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity). .

AccessionsENST00000593005.5
ENST00000592164.1
K7EK47
K7ERC3
O94910
ENST00000340736.10 [O94910-1]
K7ESH3
ENST00000672190.1 [O94910-1]
A0PJG2
ENST00000361434.8 [O94910-2]
ENST00000589616.1
ENST00000673576.1 [O94910-2]