GO_0007166 | OmnibusX

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	ANXA1-FPR2	ANXA1_HUMAN - FPR2_HUMAN	Ligand-Receptor	Signaling by Annexin
2	CD274-CD80	PD1L1_HUMAN - CD80_HUMAN	Ligand-Receptor
3	CD70-CD27	CD70_HUMAN - CD27_HUMAN	Ligand-Receptor
4	CD80-CD28	CD80_HUMAN - CD28_HUMAN	Ligand-Receptor
5	CD86-CD28	CD86_HUMAN - CD28_HUMAN	Ligand-Receptor
6	CLCF1-CNTFR+IL6ST+LIFR	CLCF1_HUMAN -	Ligand-Receptor
7	COL4A3-ADGRG6	CO4A3_HUMAN - AGRG6_HUMAN	Adhesion-Adhesion	Adhesion by Collagen/Integrin
8	CXCL10-CXCR3	CXL10_HUMAN - CXCR3_HUMAN	Ligand-Receptor	Signaling by Chemokines
9	EDN1-EDNRB	EDN1_HUMAN - EDNRB_HUMAN	Ligand-Receptor	Signaling by Endothelin
10	EDN2-EDNRB	EDN2_HUMAN - EDNRB_HUMAN	Ligand-Receptor	Signaling by Endothelin
11	EDN3-EDNRB	EDN3_HUMAN - EDNRB_HUMAN	Ligand-Receptor	Signaling by Endothelin
12	F2-GP1BA+GP1BB	THRB_HUMAN -	Ligand-Receptor	Adhesion by Prothrombin
13	GAS6-MERTK	GAS6_HUMAN - MERTK_HUMAN	Ligand-Receptor	Signaling by Growth arrest
14	GPHA2+GPHB5-TSHR	- TSHR_HUMAN	Ligand-Receptor
15	IFNA2-IFNAR1+IFNAR2	IFNA2_HUMAN -	Ligand-Receptor	Signaling by Interferon
16	IFNB1-IFNAR1+IFNAR2	IFNB_HUMAN -	Ligand-Receptor	Signaling by Interferon
17	IFNG-IFNGR1+IFNGR2	IFNG_HUMAN -	Ligand-Receptor	Signaling by Interferon
18	IL17C-IL17RA+IL17RE	IL17C_HUMAN -	Ligand-Receptor	Signaling by Interleukin
19	KLRB1-CLEC2D	KLRB1_HUMAN - CLC2D_HUMAN	Ligand-Receptor
20	RTN4R-ADGRB1	RTN4R_HUMAN - AGRB1_HUMAN	Ligand-Receptor
21	TGFA-EGFR	TGFA_HUMAN - EGFR_HUMAN	Ligand-Receptor	Signaling by Transforming growth factor

Name	cell surface receptor signaling pathway
ID	GO_0007166
collection_id	Biological process
Exact synonym	cell surface receptor linked signal transduction, cell surface receptor linked signaling pathway, cell surface receptor linked signalling pathway
Description	The series of molecular signals initiated by an extracellular ligand binding to a receptor located on the cell surface. The pathway ends with regulation of a downstream cellular process, e.g. transcription.
External URL
Genes	BSG GHRHR NPPB TRBV4-1 COL4A3 CRHR1 TRBV7-9 CXCR3 TRBV4-2 ADGRG6 FCRL5 IL2RA MAPK14 TNFRSF25 OXTR GIPR ERBB2 IGSF6 CD247 CABIN1 TRBV5-1 CBLC CLEC1A TRBV6-9 GP1BB GAS6 MARCO INHBA MS4A7 GLMN EDN3 TRBV6-1 IFNGR2 MADD LIFR IRF9 TRBV7-6 CD86 TRBV10-1 IL13RA1 TRBV6-2 TRBV16 MS4A1 TRBV6-8 CD28 TRBV5-7 MILR1 IL17C TRBV5-4 ITPKB IFNG LILRB5 DTX1 PRL ADGRG1 ADGRE4P MRGPRX1 SIGLEC9 MCHR1 SST ADGRB1 FCRL3 MS4A18 TRBV11-2 ADGRG2 NUP62 TRBV7-4 MET GPR157 MS4A10 TRBV12-3 LILRB3 MS4A2 TRBV12-5 ADGRL1 BDKRB2 KLRG1 ADGRB3 TRPA1 FCGR3A FCRL2 TRBV6-3 ADGRE5 ADGRF3 CXCL10 SCTR GLP1R CCR1 MS4A6E IFNA2 BIRC3 CTF1 LILRA6 TNFRSF13B CD36 IFITM1 CCL25 MS4A15 MS4A13 CD101 CD4 CD80 CXCL13 LY96 TRBV24-1 TGFA MS4A6A JMJD6 CD274 EDNRB EPHA1 TRBV17 PRKCZ TRBV10-2 ADGRG4 CLEC4A MERTK TRBV2 CCR5 CD3G TRB GALR2 EGFR IFNB1 PTH1R IL27RA TRBV20-1 TRBV7-1 ADRB2 TRBV11-3 ADGRF5 RTN4R MKNK2 C17orf99 CDA NTSR2 TNK2 LILRA1 MS4A12 EDN2 KLRF1 GFRA1 BAG1 GP1BA MAGI1 KIR3DX1 TRBV9 CXCR1 CD70 IL7R FCGR1BP ATP1A4 IFNAR2 ADGRD1 PTPRC FCRL4 CD3E TDP2 TRBV11-1 CXCR2 GEM PAPPA PAPPA2 TRBV12-4 PTH2R CD3D EVL ADAP1 CLEC1B GPR182 ADGRG3 TRBV7-8 NPR1 CD27 TRBV20OR9-2 TRBV7-3 ADGRG5 ADGRA3 SIRPB1 MIF ADGRD2 CD59 ADGRF2P ANXA1 DOK1 CLCF1 TRBV13 TRBV28 FCGR3B BIRC2 TRBV25-1 MS4A5 TRBV15 LY6E PECAM1 TRBV7-7 SAG TRBV7-2 LEPR PTK2B CLEC2D LAG3 FCRLB LAMA1 TRBV14 ADGRF1 ADGRL3 FCGR1A IL17RA CHRM4 RTN4RL2 KLRB1 TRBV6-4 FPR2 CD14 GCGR TRBV30 TRPV1 TNFRSF14 DOK2 IL12RB2 ADGRV1 ADGRB2 ADGRA1 BRD8 ADGRE2 LILRB2 TSHR CRHR2 CCL2 MLKL CD8A TRBV6-5 PKD1 SPN MS4A14 FCGR2B TNFRSF10B GPHA2 AGER FCRLA TRBV5-6 CYSLTR1 TIRAP FCGR2C P2RX7 TRBV27 CALCRL CCKBR ADGRG7 SEMA6A TSPAN12 TRBV18 MS4A8 INHA ADCYAP1R1 PIP4K2B TRBV29-1 TRBV3-1 KLRD1 FCER1A AGTR2 PRMT1 FCGR2A EDN1 MYD88 GLP2R PKD2 OSTN TRBV5-3 VIPR2 TRBV19 FCRL6 TRBV23-1 TRBV6-7 ADGRF4 VIPR1 TRBV6-6 ADGRL2 CSNK1A1 MAPK1 CALCR TRBV5-5 C5 HRAS P2RY1 ADGRE3 TRBV10-3 ASGR2 CD2 IL1R1 ADGRE1 KLRC1 ADGRA2 F2 TRBV4-3 PDCD1LG2 TRBV5-8 ADGRL4

cell surface receptor signaling pathway

I. Involved cell-cell interactions

II. Literature review