PAPPA2 | OmnibusX

Name	Number of supported studies	Average coverage
astrocyte	5 studies	30% ± 20%	Explore
glutamatergic neuron	5 studies	30% ± 11%	Explore
GABAergic neuron	4 studies	26% ± 10%	Explore
interneuron	4 studies	27% ± 9%	Explore
Mueller cell	4 studies	21% ± 4%	Explore
pancreatic A cell	3 studies	35% ± 7%	Explore
kidney loop of Henle epithelial cell	3 studies	30% ± 11%	Explore

Name	Number of supported studies	Average coverage
brain	3 studies	32% ± 10%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
pancreas	91%	194.21	297 / 328	44%	5.58	79 / 178
kidney	100%	3087.29	89 / 89	25%	4.98	229 / 901
brain	83%	122.56	2199 / 2642	27%	1.07	191 / 705
thymus	96%	283.60	630 / 653	7%	0.25	40 / 605
breast	98%	1331.42	448 / 459	2%	0.12	22 / 1118
bladder	86%	157.81	18 / 21	6%	0.19	31 / 504
intestine	86%	274.53	834 / 966	5%	0.80	28 / 527
adipose	91%	282.42	1101 / 1204	0%	0	0 / 0
liver	49%	161.88	110 / 226	35%	1.84	144 / 406
stomach	78%	302.92	279 / 359	5%	0.25	15 / 286
uterus	66%	338.39	112 / 170	14%	2.13	63 / 459
lung	61%	81.11	351 / 578	12%	0.40	134 / 1155
skin	65%	391.48	1169 / 1809	3%	0.23	16 / 472
blood vessel	60%	184.58	799 / 1335	0%	0	0 / 0
heart	49%	54.57	419 / 861	0%	0	0 / 0
prostate	41%	94.02	101 / 245	1%	0.02	5 / 502
esophagus	13%	16.60	187 / 1445	16%	0.64	29 / 183
adrenal gland	10%	14.07	25 / 258	6%	0.26	14 / 230
ovary	12%	20.91	22 / 180	3%	0.61	12 / 430
eye	0%	0	0 / 0	14%	0.98	11 / 80
muscle	13%	14.63	106 / 803	0%	0	0 / 0
spleen	2%	1.45	4 / 241	0%	0	0 / 0
peripheral blood	0%	0.13	2 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
lymph node	0%	0	0 / 0	0%	0	0 / 29
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
tonsil	0%	0	0 / 0	0%	0	0 / 45
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0019538	Biological process	protein metabolic process
GO_0009651	Biological process	response to salt stress
GO_0060349	Biological process	bone morphogenesis
GO_0001558	Biological process	regulation of cell growth
GO_0006508	Biological process	proteolysis
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0016324	Cellular component	apical plasma membrane
GO_0005615	Cellular component	extracellular space
GO_0070062	Cellular component	extracellular exosome
GO_0005576	Cellular component	extracellular region
GO_0004222	Molecular function	metalloendopeptidase activity
GO_0008270	Molecular function	zinc ion binding
GO_0008237	Molecular function	metallopeptidase activity

Gene name	PAPPA2
Protein name	Pappalysin-2 (EC 3.4.24.-) (Pregnancy-associated plasma protein A2) (PAPP-A2) (Pregnancy-associated plasma protein E1) (PAPP-E)
Synonyms	PLAC3
Description	FUNCTION: Metalloproteinase which specifically cleaves insulin-like growth factor binding protein (IGFBP)-5 at the '163-Ser-\|-Lys-164' bond. Shows limited proteolysis toward IGFBP-3. .
Accessions	ENST00000367662.5 [Q9BXP8-1] Q9BXP8 ENST00000367661.7 [Q9BXP8-2]

PAPPA2 report