GP1BB report

I. Expression across cell types

Insufficient scRNA-seq data for expression of GP1BB at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of GP1BB at tissue level.

III. Associated gene sets

GO_0007597Biological processblood coagulation, intrinsic pathway
GO_0010572Biological processpositive regulation of platelet activation
GO_0007155Biological processcell adhesion
GO_0051209Biological processrelease of sequestered calcium ion into cytosol
GO_0035855Biological processmegakaryocyte development
GO_0030168Biological processplatelet activation
GO_0007166Biological processcell surface receptor signaling pathway
GO_1990779Cellular componentglycoprotein Ib-IX-V complex
GO_0005886Cellular componentplasma membrane
GO_0004888Molecular functiontransmembrane signaling receptor activity
GO_0042802Molecular functionidentical protein binding
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameGP1BB
Protein namePlatelet membrane glycoprotein Ib beta
Platelet glycoprotein Ib beta chain
Truncated platelet membrane glycoprotein Ib beta
Platelet glycoprotein Ib beta chain (GP-Ib beta) (GPIb-beta) (GPIbB) (Antigen CD42b-beta) (CD antigen CD42c)
Synonyms
DescriptionFUNCTION: Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium.

AccessionsF1C636
A0A140GX62
A0A140GX61
A0A140GX63
A0A140GX60
P13224
ENST00000366425.4 [P13224-1]