platelet activation

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CD40LG-CD40CD40L_HUMAN - TNR5_HUMANLigand-Receptor
2CD40LG-ITGA2B+ITGB3CD40L_HUMAN - Ligand-Receptor
3CTSG-F2RL3CATG_HUMAN - PAR4_HUMANLigand-ReceptorSignaling by Cathepsin
4F2-F2RTHRB_HUMAN - PAR1_HUMANLigand-ReceptorAdhesion by Prothrombin
5F2-F2RL2THRB_HUMAN - PAR3_HUMANLigand-ReceptorAdhesion by Prothrombin
6F2-F2RL3THRB_HUMAN - PAR4_HUMANLigand-ReceptorAdhesion by Prothrombin
7F2-GP1BA+GP1BBTHRB_HUMAN - Ligand-ReceptorAdhesion by Prothrombin
8F2-ITGA2B+ITGB3THRB_HUMAN - Ligand-ReceptorAdhesion by Prothrombin
9F2-ITGAV+ITGB3THRB_HUMAN - Ligand-ReceptorAdhesion by Prothrombin
10VWF-GP1BA+GP1BBVWF_HUMAN - Ligand-ReceptorSignaling by von Willebrand factor
11VWF-ITGAV+ITGB3VWF_HUMAN - Ligand-ReceptorSignaling by von Willebrand factor

II. Literature review

[source]
Nameplatelet activation
IDGO_0030168
collection_id

Biological process

Exact synonym

blood coagulation, platelet activation

Description

A series of progressive, overlapping events triggered by exposure of the platelets to subendothelial tissue. These events include shape change, adhesiveness, aggregation, and release reactions. When carried through to completion, these events lead to the formation of a stable hemostatic plug.

External URL
Genes