Insufficient scRNA-seq data for expression of DGKK at single-cell level.
Insufficient scRNA-seq data for expression of DGKK at tissue level.
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 38% | 150.80 | 97 / 258 | 65% | 29.41 | 149 / 230 |
brain | 52% | 225.29 | 1379 / 2642 | 40% | 2.50 | 282 / 705 |
peripheral blood | 47% | 62.07 | 436 / 929 | 0% | 0 | 0 / 0 |
spleen | 36% | 11.07 | 86 / 241 | 0% | 0 | 0 / 0 |
lung | 28% | 11.16 | 162 / 578 | 1% | 0.06 | 11 / 1155 |
stomach | 20% | 9.31 | 71 / 359 | 1% | 0.26 | 2 / 286 |
ovary | 3% | 5.64 | 6 / 180 | 15% | 0.73 | 63 / 430 |
prostate | 6% | 2.24 | 14 / 245 | 2% | 0.26 | 11 / 502 |
liver | 1% | 0.26 | 3 / 226 | 5% | 0.15 | 19 / 406 |
bladder | 0% | 0 | 0 / 21 | 4% | 0.19 | 21 / 504 |
uterus | 1% | 0.19 | 1 / 170 | 3% | 0.11 | 12 / 459 |
adipose | 3% | 0.79 | 37 / 1204 | 0% | 0 | 0 / 0 |
esophagus | 1% | 0.42 | 12 / 1445 | 2% | 0.04 | 3 / 183 |
thymus | 2% | 0.72 | 15 / 653 | 0% | 0 | 0 / 605 |
pancreas | 0% | 0.05 | 1 / 328 | 2% | 0.06 | 3 / 178 |
kidney | 1% | 0.18 | 1 / 89 | 0% | 0.01 | 4 / 901 |
breast | 1% | 0.21 | 5 / 459 | 0% | 0.01 | 5 / 1118 |
intestine | 0% | 0.12 | 4 / 966 | 0% | 0.01 | 2 / 527 |
heart | 1% | 0.12 | 5 / 861 | 0% | 0 | 0 / 0 |
skin | 0% | 0.56 | 6 / 1809 | 0% | 0.01 | 1 / 472 |
blood vessel | 0% | 0.15 | 4 / 1335 | 0% | 0 | 0 / 0 |
muscle | 0% | 0.03 | 1 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 45 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0006654 | Biological process | phosphatidic acid biosynthetic process |
GO_0046339 | Biological process | diacylglycerol metabolic process |
GO_0035556 | Biological process | intracellular signal transduction |
GO_0006979 | Biological process | response to oxidative stress |
GO_0030168 | Biological process | platelet activation |
GO_0046834 | Biological process | lipid phosphorylation |
GO_0007205 | Biological process | protein kinase C-activating G protein-coupled receptor signaling pathway |
GO_0005886 | Cellular component | plasma membrane |
GO_0004143 | Molecular function | ATP-dependent diacylglycerol kinase activity |
GO_0046872 | Molecular function | metal ion binding |
GO_0005524 | Molecular function | ATP binding |
Gene name | DGKK |
Protein name | Alternative protein DGKK Diacylglycerol kinase kappa (DAG kinase kappa) (DGK-kappa) (EC 2.7.1.107) (142 kDa diacylglycerol kinase) (Diglyceride kinase kappa) |
Synonyms | |
Description | FUNCTION: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). . |
Accessions | Q5KSL6 L8EC67 ENST00000611977.2 |