DGKK report

I. Expression across cell types

Insufficient scRNA-seq data for expression of DGKK at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of DGKK at tissue level.

III. Associated gene sets

GO_0006654Biological processphosphatidic acid biosynthetic process
GO_0046339Biological processdiacylglycerol metabolic process
GO_0035556Biological processintracellular signal transduction
GO_0006979Biological processresponse to oxidative stress
GO_0030168Biological processplatelet activation
GO_0046834Biological processlipid phosphorylation
GO_0007205Biological processprotein kinase C-activating G protein-coupled receptor signaling pathway
GO_0005886Cellular componentplasma membrane
GO_0004143Molecular functionATP-dependent diacylglycerol kinase activity
GO_0046872Molecular functionmetal ion binding
GO_0005524Molecular functionATP binding

IV. Literature review

[source]
Gene nameDGKK
Protein nameAlternative protein DGKK
Diacylglycerol kinase kappa (DAG kinase kappa) (DGK-kappa) (EC 2.7.1.107) (142 kDa diacylglycerol kinase) (Diglyceride kinase kappa)
Synonyms
DescriptionFUNCTION: Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids . Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes (Probable). .

AccessionsQ5KSL6
L8EC67
ENST00000611977.2