GP1BA | OmnibusX

Name	Number of supported studies	Average coverage
platelet	8 studies	29% ± 12%	Explore
megakaryocyte	5 studies	67% ± 23%	Explore

sc-RNAseq data

Insufficient scRNA-seq data for expression of GP1BA at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
kidney	97%	61.27	86 / 89	69%	1.73	622 / 901
esophagus	95%	58.79	1366 / 1445	71%	2.29	130 / 183
lung	99%	207.59	572 / 578	58%	1.50	668 / 1155
skin	98%	214.65	1780 / 1809	55%	4.03	261 / 472
thymus	96%	69.03	626 / 653	53%	1.62	320 / 605
brain	80%	47.00	2124 / 2642	62%	1.12	435 / 705
intestine	97%	113.29	940 / 966	41%	1.11	216 / 527
breast	85%	58.07	390 / 459	49%	1.40	543 / 1118
prostate	96%	61.18	234 / 245	37%	0.60	187 / 502
stomach	80%	41.50	286 / 359	52%	1.27	150 / 286
ovary	88%	50.19	159 / 180	37%	0.71	159 / 430
liver	96%	62.68	217 / 226	24%	0.83	98 / 406
uterus	94%	56.22	159 / 170	21%	0.46	96 / 459
bladder	86%	53.62	18 / 21	26%	0.64	132 / 504
lymph node	0%	0	0 / 0	100%	26.39	29 / 29
spleen	100%	248.81	241 / 241	0%	0	0 / 0
peripheral blood	99%	244.26	921 / 929	0%	0	0 / 0
pancreas	49%	17.44	161 / 328	43%	1.71	76 / 178
adipose	85%	47.77	1026 / 1204	0%	0	0 / 0
blood vessel	85%	46.67	1135 / 1335	0%	0	0 / 0
heart	81%	38.05	699 / 861	0%	0	0 / 0
muscle	81%	49.21	650 / 803	0%	0	0 / 0
adrenal gland	30%	9.18	77 / 258	27%	0.46	63 / 230
tonsil	0%	0	0 / 0	56%	3.22	25 / 45
eye	0%	0	0 / 0	8%	0.12	6 / 80
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0
ureter	0%	0	0 / 0	0%	0	0 / 1

GO_0007155	Biological process	cell adhesion
GO_0070493	Biological process	thrombin-activated receptor signaling pathway
GO_0007596	Biological process	blood coagulation
GO_0051209	Biological process	release of sequestered calcium ion into cytosol
GO_0042730	Biological process	fibrinolysis
GO_0035855	Biological process	megakaryocyte development
GO_0030168	Biological process	platelet activation
GO_1903238	Biological process	positive regulation of leukocyte tethering or rolling
GO_0030193	Biological process	regulation of blood coagulation
GO_0007597	Biological process	blood coagulation, intrinsic pathway
GO_0000902	Biological process	cell morphogenesis
GO_0010572	Biological process	positive regulation of platelet activation
GO_0007166	Biological process	cell surface receptor signaling pathway
GO_0005615	Cellular component	extracellular space
GO_0009897	Cellular component	external side of plasma membrane
GO_1990779	Cellular component	glycoprotein Ib-IX-V complex
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0070062	Cellular component	extracellular exosome
GO_0031012	Cellular component	extracellular matrix
GO_0009986	Cellular component	cell surface
GO_0015057	Molecular function	thrombin-activated receptor activity
GO_0005515	Molecular function	protein binding

Gene name	GP1BA
Protein name	Platelet glycoprotein Ib alpha polypeptide type 3 Platelet glycoprotein Ib alpha chain (GP-Ib alpha) (GPIb-alpha) (GPIbA) (Glycoprotein Ibalpha) (Antigen CD42b-alpha) (CD antigen CD42b) [Cleaved into: Glycocalicin] Mutant platelet membrane glycoprotein Ib-alpha Platelet glycoprotein Ib alpha polypeptide type 2 Glycoprotein Ib alpha polypeptide T624 deletion mutant Platelet glycoprotein Ib alpha Platelet membrane glycoprotein Ib-alpha Glycoprotein Ib alpha polypeptide A1562T1563 deletion mutant Glycoprotein Ib alpha polypeptide G942 deletion mutant Platelet glycoprotein Ib alpha polypeptide type 4
Synonyms
Description	FUNCTION: GP-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to the A1 domain of vWF, which is already bound to the subendothelium.
Accessions	E0D851 A0A193AUC0 E0D852 L7UV37 E0D853 A0A193AU54 L7URT5 A0A193AUV8 A5CKE2 ENST00000329125.6 E0D854 A0A193AUJ5 L7UYB8 P07359

GP1BA report