BLOC1S3 | OmnibusX

sc-RNAseq data

Insufficient scRNA-seq data for expression of BLOC1S3 at tissue level.

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
esophagus	100%	666.15	1445 / 1445	100%	17.53	183 / 183
liver	100%	495.57	226 / 226	100%	14.03	406 / 406
skin	100%	1302.60	1809 / 1809	100%	22.25	472 / 472
stomach	100%	618.45	359 / 359	100%	17.97	286 / 286
thymus	100%	614.88	653 / 653	100%	13.32	605 / 605
uterus	100%	646.07	170 / 170	100%	20.57	459 / 459
intestine	100%	690.67	966 / 966	100%	18.09	526 / 527
prostate	100%	719.50	245 / 245	100%	17.19	501 / 502
brain	100%	612.15	2636 / 2642	100%	15.49	705 / 705
ovary	100%	542.60	180 / 180	100%	17.58	429 / 430
bladder	100%	804.10	21 / 21	100%	20.81	502 / 504
adrenal gland	100%	723.81	258 / 258	100%	13.83	229 / 230
kidney	100%	536.12	89 / 89	99%	13.09	896 / 901
breast	100%	718.96	459 / 459	99%	23.77	1111 / 1118
lung	100%	692.23	577 / 578	99%	18.50	1149 / 1155
pancreas	99%	408.44	324 / 328	100%	17.97	178 / 178
adipose	100%	726.19	1204 / 1204	0%	0	0 / 0
blood vessel	100%	695.30	1335 / 1335	0%	0	0 / 0
eye	0%	0	0 / 0	100%	19.13	80 / 80
lymph node	0%	0	0 / 0	100%	22.15	29 / 29
spleen	100%	1290.61	241 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	100%	18.61	45 / 45
ureter	0%	0	0 / 0	100%	24.16	1 / 1
heart	98%	347.54	847 / 861	0%	0	0 / 0
peripheral blood	98%	1028.88	913 / 929	0%	0	0 / 0
muscle	93%	311.27	750 / 803	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

GO_0035646	Biological process	endosome to melanosome transport
GO_0031175	Biological process	neuron projection development
GO_0008089	Biological process	anterograde axonal transport
GO_0033299	Biological process	secretion of lysosomal enzymes
GO_0032438	Biological process	melanosome organization
GO_0032402	Biological process	melanosome transport
GO_0001654	Biological process	eye development
GO_0030168	Biological process	platelet activation
GO_0048490	Biological process	anterograde synaptic vesicle transport
GO_0060155	Biological process	platelet dense granule organization
GO_0032816	Biological process	positive regulation of natural killer cell activation
GO_0043473	Biological process	pigmentation
GO_0009410	Biological process	response to xenobiotic stimulus
GO_0071806	Biological process	protein transmembrane transport
GO_0005829	Cellular component	cytosol
GO_0031083	Cellular component	BLOC-1 complex
GO_0030133	Cellular component	transport vesicle
GO_1904115	Cellular component	axon cytoplasm
GO_0008320	Molecular function	protein transmembrane transporter activity
GO_0003674	Molecular function	molecular_function
GO_0005515	Molecular function	protein binding

Gene name	BLOC1S3
Protein name	Biogenesis of lysosome-related organelles complex 1 subunit 3 (BLOC-1 subunit 3) Biogenesis of lysosome-related organelles complex 1 subunit 3
Synonyms	BLOS3
Description	FUNCTION: Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking. .
Accessions	ENST00000592910.1 ENST00000587722.1 ENST00000433642.3 Q6QNY0 K7EN58

BLOC1S3 report