response to xenobiotic stimulus

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1CDH1-ITGA2+ITGB1CADH1_HUMAN - Adhesion-AdhesionAdhesion by Cadherin
2COL18A1-ITGA2+ITGB1COIA1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
3COL1A1-ITGA2+ITGB1CO1A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
4COL6A1-ITGA2+ITGB1CO6A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
5DBH+SLC6A2-ADRA1A - ADA1A_HUMANLigand-ReceptorSignaling by Noradrenaline
6DDC+SLC6A3-DRD1 - DRD1_HUMANLigand-ReceptorSignaling by Serotonin/Dopamine
7DDC+SLC6A3-DRD2 - DRD2_HUMANLigand-ReceptorSignaling by Serotonin/Dopamine
8DDC+SLC6A3-DRD3 - DRD3_HUMANLigand-ReceptorSignaling by Serotonin/Dopamine
9GLS2+SLC1A1-GRIA1 - GRIA1_HUMANLigand-ReceptorSignaling by Glutamate
10GLS2+SLC1A1-GRIN1+GRIN2A - Ligand-ReceptorSignaling by Glutamate
11GLS2+SLC1A2-GRIA1 - GRIA1_HUMANLigand-ReceptorSignaling by Glutamate
12GLS2+SLC1A2-GRIN1+GRIN2A - Ligand-ReceptorSignaling by Glutamate
13GLS2+SLC1A3-GRIA1 - GRIA1_HUMANLigand-ReceptorSignaling by Glutamate
14GLS2+SLC1A3-GRIN1+GRIN2A - Ligand-ReceptorSignaling by Glutamate
15GLS+SLC1A1-GRIA1 - GRIA1_HUMANLigand-ReceptorSignaling by Glutamate
16GLS+SLC1A1-GRIN1+GRIN2A - Ligand-ReceptorSignaling by Glutamate
17GLS+SLC1A2-GRIA1 - GRIA1_HUMANLigand-ReceptorSignaling by Glutamate
18GLS+SLC1A2-GRIN1+GRIN2A - Ligand-ReceptorSignaling by Glutamate
19GLS+SLC1A3-GRIA1 - GRIA1_HUMANLigand-ReceptorSignaling by Glutamate
20GLS+SLC1A3-GRIN1+GRIN2A - Ligand-ReceptorSignaling by Glutamate
21SLC6A4+TPH1-HTR2A - 5HT2A_HUMANLigand-ReceptorSignaling by Serotonin
22SLC6A4+TPH1-HTR2B - 5HT2B_HUMANLigand-ReceptorSignaling by Serotonin
23SLC6A4+TPH2-HTR2A - 5HT2A_HUMANLigand-ReceptorSignaling by Serotonin
24SLC6A4+TPH2-HTR2B - 5HT2B_HUMANLigand-ReceptorSignaling by Serotonin
25TGFB1-ACVR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
26TGFB1-TGFBR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
27THBS1-ITGA3+ITGB1TSP1_HUMAN - Ligand-ReceptorAdhesion by Thrombospondin

II. Literature review

[source]
Nameresponse to xenobiotic stimulus
IDGO_0009410
collection_id

Biological process

Alternative ID

GO:0017035, GO:0017104, GO:0042493

Description

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a xenobiotic, a compound foreign to the organism exposed to it. It may be synthesized by another organism (like ampicilin) or it can be a synthetic chemical.

Related synonym

drug resistance, drug susceptibility/resistance, response to drug

External URL
Genes
DRD3ITGA2FOXO3PTGS2NFKBIZENGAPOA2AMELXPARP4OXTRSFRP1IGFBP2HTR2BMDM2SLC1A2CASP3SRD5A2BLOC1S6CA9NPAS2CDKN1AUMODGAD2BCL2PTPRMNKX6-1GABRG3BAK1XPCSLC6A2ABATPMS2ABCG8SCNN1BDUSP6ERRFI1BLOC1S3ACECPT1APMS1PDX1SRRPLIN2ATP4ATHBS1SEMA3CMT-CYBMYCRETADORA2AFOSBBECN1TFAP2BSOD1ADAM17SHANK2SCGB1A1GALABCC9SSTPRICKLE1GRIA1RPP21ABCC8BGLAPATRSLC22A12SLC34A1SFRP2FOSCATCALRNTRK1LHCGRTRPA1ABCD3SLC1A3ADD3MYO6TNFRSF11BCCND1RAD54LMT-ND1SLC6A11PTCH1ABCC6LCKMTHFRGRIN2ATXN2RAD54BNCKAP1LSS18PRKCBRELAHADHADCY1SRCKCNJ8CPS1TGFB1STAT1LRP8ABCG5PTHTYMSTGIF1XRCC5XRCC1CCNONFATC2EMX2CDH3HSPG2RPTORMMP2ITGA3GPR52MAP1BSREBF1RHBDD3GNPATAHRACACBCOL18A1TP53I13SLC12A5HMGCS2MBD1CHUKRAB6CATG5MMP7HSD11B2NEUROD1SMTNL1CYBBSLITRK5TRAF3IP2CD38SNCAFOSL1OGG1CPB2ABCB1ABCA3VEGFCHADHAOTCRPS6KB1DVL3HSPA8CDK4COMTLTASCN11ACENPFTIGARDRD1SLC6A4LOXFZD3HDAC5LYNPFASHDAC2GATA6TXNIPTXNRD2BLMHFGF8PTK2BSRD5A1ASS1PCSK1OXSR1ALADADRA1ANPC1FZD1CCNT1KCNJ11ABCC1EMX1SMPD1AMHCARD9KCNK3SOD2TGFBR2VAV3MAP2K6CSAG2GCLCTP73CDKN1BP2RX7DRD2CTPS1ABL1GPX1NPPCBCAR3MAS1PDE3AGIPLIPAADCYAP1R1SRP68TNFNNMTIL10ABCA2CREB1FECHMAOBCDH1CTNNB1COL6A1FKRPAGPAT2FOSL2SLC26A5UBE2BTOP1GNA12GATA4COL1A1CDK1USP47CRHSLC6A3SLC1A1GCLMTENT4AATP1A1DNMT3ATBXA2RTSPOHTR2APNPHSP90AA1