Name | Number of supported studies | Average coverage | |
---|---|---|---|
lung | 18 studies | 77% ± 21% | |
peripheral blood | 17 studies | 89% ± 9% | |
brain | 13 studies | 56% ± 25% | |
intestine | 12 studies | 89% ± 11% | |
kidney | 7 studies | 79% ± 22% | |
liver | 6 studies | 82% ± 12% | |
eye | 6 studies | 74% ± 23% | |
bone marrow | 5 studies | 90% ± 6% | |
lymph node | 4 studies | 90% ± 6% | |
breast | 4 studies | 94% ± 2% | |
heart | 3 studies | 42% ± 16% | |
uterus | 3 studies | 97% ± 0% | |
prostate | 3 studies | 99% ± 0% | |
esophagus | 3 studies | 71% ± 24% | |
skin | 3 studies | 91% ± 5% | |
adipose | 3 studies | 83% ± 9% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
adrenal gland | 100% | 792837.82 | 258 / 258 | 100% | 21546.53 | 229 / 230 |
liver | 99% | 760438.11 | 224 / 226 | 100% | 12954.37 | 406 / 406 |
brain | 100% | 1262014.27 | 2637 / 2642 | 99% | 14254.36 | 696 / 705 |
kidney | 99% | 1245510.20 | 88 / 89 | 99% | 18659.21 | 889 / 901 |
stomach | 99% | 665969.88 | 357 / 359 | 96% | 13101.42 | 275 / 286 |
breast | 98% | 644013.50 | 451 / 459 | 97% | 11171.35 | 1087 / 1118 |
pancreas | 96% | 299082.56 | 315 / 328 | 99% | 10846.89 | 176 / 178 |
prostate | 96% | 419806.24 | 234 / 245 | 99% | 12099.90 | 495 / 502 |
esophagus | 92% | 395592.73 | 1336 / 1445 | 100% | 12828.79 | 183 / 183 |
intestine | 96% | 571763.09 | 931 / 966 | 94% | 10182.93 | 496 / 527 |
bladder | 95% | 369884.10 | 20 / 21 | 95% | 11009.37 | 478 / 504 |
skin | 87% | 383506.78 | 1570 / 1809 | 95% | 9816.51 | 448 / 472 |
lung | 83% | 281158.60 | 481 / 578 | 92% | 8940.55 | 1066 / 1155 |
thymus | 77% | 257552.94 | 501 / 653 | 97% | 10510.44 | 589 / 605 |
uterus | 71% | 175974.42 | 121 / 170 | 93% | 8030.49 | 427 / 459 |
ovary | 53% | 130748.67 | 95 / 180 | 100% | 18060.65 | 430 / 430 |
eye | 0% | 0 | 0 / 0 | 100% | 20689.82 | 80 / 80 |
muscle | 100% | 1026985.62 | 803 / 803 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 100% | 6104.77 | 45 / 45 |
ureter | 0% | 0 | 0 / 0 | 100% | 31683.09 | 1 / 1 |
heart | 100% | 1467835.69 | 860 / 861 | 0% | 0 | 0 / 0 |
adipose | 98% | 672494.62 | 1183 / 1204 | 0% | 0 | 0 / 0 |
spleen | 86% | 287143.88 | 208 / 241 | 0% | 0 | 0 / 0 |
blood vessel | 73% | 203258.96 | 971 / 1335 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 69% | 4247.75 | 20 / 29 |
peripheral blood | 24% | 53018.81 | 226 / 929 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
GO_0032981 | Biological process | mitochondrial respiratory chain complex I assembly |
GO_0014070 | Biological process | response to organic cyclic compound |
GO_0033194 | Biological process | response to hydroperoxide |
GO_0009410 | Biological process | response to xenobiotic stimulus |
GO_0009060 | Biological process | aerobic respiration |
GO_0001666 | Biological process | response to hypoxia |
GO_0006120 | Biological process | mitochondrial electron transport, NADH to ubiquinone |
GO_0042776 | Biological process | proton motive force-driven mitochondrial ATP synthesis |
GO_0055085 | Biological process | transmembrane transport |
GO_0031966 | Cellular component | mitochondrial membrane |
GO_0045271 | Cellular component | respiratory chain complex I |
GO_0043025 | Cellular component | neuronal cell body |
GO_0005743 | Cellular component | mitochondrial inner membrane |
GO_0030425 | Cellular component | dendrite |
GO_0003954 | Molecular function | NADH dehydrogenase activity |
GO_0005515 | Molecular function | protein binding |
GO_0008137 | Molecular function | NADH dehydrogenase (ubiquinone) activity |
Gene name | MT-ND1 |
Protein name | NADH-ubiquinone oxidoreductase chain 1 (EC 7.1.1.2) (NADH dehydrogenase subunit 1) |
Synonyms | ND1 NADH1 MTND1 |
Description | FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor . Essential for the catalytic activity and assembly of complex I . . |
Accessions | ENST00000361390.2 P03886 |