naive B cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
FCER21949% ± 16%03
BLK1932% ± 10%05
VPREB31947% ± 17%07
FCRL11835% ± 12%03
TNFRSF13C1743% ± 13%04
FCRLA1736% ± 14%05
CD191745% ± 12%08
TCL1A2064% ± 19%17
MS4A12088% ± 8%19
CD79A2090% ± 7%113
PAX51930% ± 10%17
CD721937% ± 14%18
FCMR2056% ± 16%127
NIBAN31747% ± 18%16
HLA-DOA1625% ± 10%19
BANK12062% ± 12%29
CD79B2067% ± 15%213
CD221943% ± 14%28
BTK1926% ± 9%217
CYB561A31836% ± 11%215
PLEKHF21726% ± 7%212
STAP11623% ± 5%26
HVCN12047% ± 14%312
TMEM1541822% ± 5%312
NCF12060% ± 16%336
CCR71836% ± 12%317
SP1401927% ± 8%328
CD401936% ± 8%416
CD832057% ± 20%429
ADAM281840% ± 6%417

III. Associated gene sets

GO_0051712Biological processpositive regulation of killing of cells of another organism
GO_0050851Biological processantigen receptor-mediated signaling pathway
GO_0002768Biological processimmune response-regulating cell surface receptor signaling pathway
GO_1903980Biological processpositive regulation of microglial cell activation
GO_1903376Biological processregulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway
GO_0071467Biological processcellular response to pH
GO_0002925Biological processpositive regulation of humoral immune response mediated by circulating immunoglobulin
GO_0098761Biological processcellular response to interleukin-7
GO_1990959Biological processeosinophil homeostasis
GO_0002115Biological processstore-operated calcium entry
GO_0050861Biological processpositive regulation of B cell receptor signaling pathway
GO_0038095Biological processFc-epsilon receptor signaling pathway
GO_0032732Biological processpositive regulation of interleukin-1 production
GO_0002503Biological processpeptide antigen assembly with MHC class II protein complex
GO_0009268Biological processresponse to pH
GO_0002322Biological processB cell proliferation involved in immune response
GO_0045069Biological processregulation of viral genome replication
GO_0033590Biological processresponse to cobalamin
GO_1904178Biological processnegative regulation of adipose tissue development
GO_0030592Biological processDNA ADP-ribosylation
GO_0031296Biological processB cell costimulation
GO_0048304Biological processpositive regulation of isotype switching to IgG isotypes
GO_0072540Biological processT-helper 17 cell lineage commitment
GO_0050855Biological processregulation of B cell receptor signaling pathway
GO_1902227Biological processnegative regulation of macrophage colony-stimulating factor signaling pathway
GO_1905665Biological processpositive regulation of calcium ion import across plasma membrane
GO_0060100Biological processpositive regulation of phagocytosis, engulfment
GO_1904151Biological processpositive regulation of microglial cell mediated cytotoxicity
GO_0019724Biological processB cell mediated immunity
GO_0036010Biological processprotein localization to endosome

IV. Literature review

[source]
Cell type namenaive B cell
Synonymsnaive B lymphocyte
naive B-cell
naive B-lymphocyte
DescriptionA naive B cell is a mature B cell that has the phenotype surface IgD-positive, surface IgM-positive, CD20-positive, CD27-negative and that has not yet been activated by antigen in the periphery.
ParentCL_0000785