PLEKHF2 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

GO_0015031Biological processprotein transport
GO_0008333Biological processendosome to lysosome transport
GO_0007032Biological processendosome organization
GO_0031901Cellular componentearly endosome membrane
GO_0030133Cellular componenttransport vesicle
GO_0005783Cellular componentendoplasmic reticulum
GO_0005769Cellular componentearly endosome
GO_0005515Molecular functionprotein binding
GO_0035091Molecular functionphosphatidylinositol binding
GO_0046872Molecular functionmetal ion binding

IV. Literature review

[source]
Gene namePLEKHF2
Protein namePleckstrin homology domain-containing family F member 2 (PH domain-containing family F member 2) (Endoplasmic reticulum-associated apoptosis-involved protein containing PH and FYVE domains) (EAPF) (PH and FYVE domain-containing protein 2) (Phafin-2) (Phafin2) (Zinc finger FYVE domain-containing protein 18)
SynonymsZFYVE18
DescriptionFUNCTION: May play a role in early endosome fusion upstream of RAB5, hence regulating receptor trafficking and fluid-phase transport. Enhances cellular sensitivity to TNF-induced apoptosis . .

AccessionsENST00000315367.4
ENST00000700745.1
ENST00000700749.1
ENST00000700748.1
Q9H8W4
ENST00000519516.1
ENST00000700746.1