early endosome

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1APP-SORL1A4_HUMAN - SORL_HUMANLigand-ReceptorSignaling by Amyloid-beta precursor protein
2HFE-TFRCHFE_HUMAN - TFR1_HUMANLigand-Receptor
3TF-TFRCTRFE_HUMAN - TFR1_HUMANLigand-ReceptorSignaling by Transferrin

II. Literature review

[source]
Nameearly endosome
IDGO_0005769
collection_id

Cellular component

Description

A membrane-bounded organelle that receives incoming material from primary endocytic vesicles that have been generated by clathrin-dependent and clathrin-independent endocytosis; vesicles fuse with the early endosome to deliver cargo for sorting into recycling or degradation pathways.

External URL
Genes
ALS2SLC5A1WDFY1ap3b_s3b_humanSLC9A9AP3S2NME1MVB12BPXKCYTIPHAS3TMEM108SNX27ZFYVE9TRIM27PTP4A1HSPD1NISCHATP6V0D1LAMP3TBCKDIAPH2WASH3PKCNQ1KIF16BANKRD13BMMEUSP10STAMBPTMEM127TSG101TICAM1STX6APBB2ZFYVE16RABEP2MGRN1MAPK3TRIM3RAB5APTP4A3EHD3ap3a_s3a_humanWDFY4NUMBATP11AHGSC1orf210NIPA2DERL2WDFY2GGA1NCSTNRCSD1CFTRSLC9A3LIPGCLTCL1ABCB9PCSK9RAB22AANKRD27MYO1DHAP1NAPEPLDMYO5ACCDC93FLOT1IGF2RKIAA0319LTFVPS16RHOBSAMD9LVPS26BSNX16ECPASMAPK1ACKR2TOLLIPVPS29SERPINB1PSEN2GPR107AP1B1RAB5BATP9APTPN1HLA-GAPOA2NOX1ITCHSTEAP2APPAP1G1CXCR4DYSFSGK3CD22AKT2SORL1RETLDLRAP1EEA1SNX17SLC2A13RAB17APOBMMGT1TFSNX4ap1a_s1c_humanFGD5ENTR1RABGAP1LUSP8F8A1LRP1PHETA1ARRDC3PTP4A2TM9SF4AP1S2ACKR3APOElrp1_human-1WASH2PMYO1BNEURL3RAB38ATP6V0D2bloc2_humanF2RCACNG7ap3a_s3b_humanRHODEHD4CORO1AEHD2TFRCMAP2K2ASTN2CLN3WASHC2AAPPL1WASHC5RAB14ap3b_s3a_humanSTX8RABGEF1ANKFY1VPS35PRDX3CD1EDBNLBACE1PHETA2SLC30A10WIPF3AP1S3AP3B1NEURL1BRAP1ACLCN4CNTNAP2SNX30CHMP3APOC2VPS11PLEKHF2LMTK2PLPP2MIB2OCRLSH3GL2ap1a_s1b_humanWASHC1ANGPTL3RND2VPS28TRAK2PLD4TRAK1RUBCNHPS3ARRDC4WASH4PSORT1SNX3SLC11A2APOC3RAB31RNF11MICALL1VPS18VIPAS39ST8SIA2MLC1AP1M1SIAH2PLEKHA3EHD1CCDC154ANK2LRP6AP3D1abeta-42-oligomer_humanSNX31ADRB2AP3B2VPS4ARAB11FIP5PARM1HPS5KDRAP1S1APH1AGPER1RASGEF1BAPOA5TBC1D16CHMP1ANRP1CACFD1RPS6KC1TOM1TLR4SNX12RAB21PTPN23FKBP15PHB1NF2CLN6RFTN1ZFYVE26HYAL3WLSPACSIN2LDLRAOC3KIFC1ERBB2F2RL1AP3S1WASHC2CDERL1TMEM230DNERPLEKHJ1HPS6BLTP3BPICALMTGFBRAP1ANXA2AP4M1WASF2NTRK2NTRK1RAP1GAPCOMMD1AP3M1TLR3CRYZL1ferry_humanRABEP1CD4SIGLEC1TBC1D2BRAB29VPS33AINPP5FHFEAP1ARCLCN5BLOC1S1EPHA3HTTNIPA1PLEKHF1APOA4FERRY3HAVCR2MAP2K1NSG2ACKR4VPS26ARAB32MAGEL2GATD1AP3M2ACKR1CTNSPPP1R21DTX3LRIN3ap1a_s1a_humanVPS8ASAH1APOA1SNX7RUSC1RAPGEF1CLCN3VCAM1VAMP8STX7MELTFADRB1WASH6PSNX13UVRAGRAB1ALAPTM4B