Name | Number of supported studies | Average coverage | |
---|---|---|---|
macrophage | 46 studies | 45% ± 16% | |
classical monocyte | 27 studies | 45% ± 14% | |
conventional dendritic cell | 27 studies | 38% ± 16% | |
monocyte | 23 studies | 42% ± 16% | |
non-classical monocyte | 21 studies | 40% ± 13% | |
fibroblast | 20 studies | 25% ± 9% | |
dendritic cell | 19 studies | 45% ± 15% | |
myeloid cell | 17 studies | 52% ± 15% | |
astrocyte | 16 studies | 37% ± 17% | |
oligodendrocyte precursor cell | 15 studies | 57% ± 20% | |
pericyte | 15 studies | 28% ± 11% | |
microglial cell | 15 studies | 48% ± 17% | |
smooth muscle cell | 13 studies | 21% ± 3% | |
type I pneumocyte | 11 studies | 41% ± 14% | |
endothelial cell | 11 studies | 24% ± 4% | |
ciliated cell | 10 studies | 25% ± 8% | |
alveolar macrophage | 8 studies | 48% ± 17% | |
platelet | 8 studies | 23% ± 7% | |
connective tissue cell | 8 studies | 32% ± 17% | |
endothelial cell of lymphatic vessel | 8 studies | 19% ± 3% | |
basal cell | 7 studies | 22% ± 6% | |
neutrophil | 7 studies | 29% ± 7% | |
mononuclear phagocyte | 7 studies | 41% ± 9% | |
myofibroblast cell | 6 studies | 26% ± 11% | |
retinal ganglion cell | 5 studies | 41% ± 17% | |
retina horizontal cell | 5 studies | 38% ± 11% | |
memory B cell | 5 studies | 18% ± 3% | |
type II pneumocyte | 5 studies | 19% ± 5% | |
squamous epithelial cell | 4 studies | 32% ± 13% | |
GABAergic neuron | 4 studies | 33% ± 6% | |
leukocyte | 4 studies | 26% ± 12% | |
intermediate monocyte | 4 studies | 52% ± 19% | |
club cell | 4 studies | 25% ± 10% | |
epithelial cell | 3 studies | 25% ± 7% | |
mesothelial cell | 3 studies | 20% ± 4% | |
tissue-resident macrophage | 3 studies | 49% ± 7% | |
muscle cell | 3 studies | 20% ± 6% | |
glutamatergic neuron | 3 studies | 33% ± 12% | |
interneuron | 3 studies | 24% ± 10% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
brain | 98% | 9473.91 | 2576 / 2642 | 100% | 330.61 | 704 / 705 |
breast | 98% | 4452.69 | 449 / 459 | 95% | 139.54 | 1064 / 1118 |
lung | 100% | 8425.20 | 576 / 578 | 93% | 77.63 | 1073 / 1155 |
uterus | 99% | 8914.81 | 169 / 170 | 87% | 70.10 | 398 / 459 |
thymus | 99% | 5732.61 | 648 / 653 | 85% | 47.29 | 516 / 605 |
esophagus | 98% | 8727.06 | 1416 / 1445 | 84% | 56.18 | 153 / 183 |
bladder | 100% | 8187.48 | 21 / 21 | 71% | 50.51 | 360 / 504 |
kidney | 79% | 2727.85 | 70 / 89 | 85% | 51.65 | 770 / 901 |
ovary | 100% | 8693.82 | 180 / 180 | 62% | 25.59 | 265 / 430 |
adrenal gland | 100% | 20723.26 | 258 / 258 | 56% | 33.96 | 128 / 230 |
intestine | 93% | 6817.60 | 897 / 966 | 58% | 33.91 | 308 / 527 |
prostate | 94% | 4565.07 | 231 / 245 | 45% | 13.95 | 227 / 502 |
skin | 75% | 3397.61 | 1349 / 1809 | 56% | 26.56 | 262 / 472 |
stomach | 60% | 5542.78 | 215 / 359 | 69% | 38.76 | 198 / 286 |
blood vessel | 100% | 16466.96 | 1335 / 1335 | 0% | 0 | 0 / 0 |
adipose | 100% | 6665.09 | 1202 / 1204 | 0% | 0 | 0 / 0 |
spleen | 100% | 5113.68 | 240 / 241 | 0% | 0 | 0 / 0 |
pancreas | 7% | 181.13 | 23 / 328 | 92% | 93.31 | 163 / 178 |
peripheral blood | 92% | 9235.53 | 859 / 929 | 0% | 0 | 0 / 0 |
tonsil | 0% | 0 | 0 / 0 | 91% | 67.82 | 41 / 45 |
lymph node | 0% | 0 | 0 / 0 | 72% | 35.53 | 21 / 29 |
heart | 58% | 1851.09 | 502 / 861 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 25% | 8.22 | 20 / 80 |
liver | 2% | 63.42 | 5 / 226 | 12% | 4.58 | 48 / 406 |
muscle | 4% | 114.93 | 35 / 803 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0031623 | Biological process | receptor internalization |
GO_0032869 | Biological process | cellular response to insulin stimulus |
GO_0090382 | Biological process | phagosome maturation |
GO_0006886 | Biological process | intracellular protein transport |
GO_0045055 | Biological process | regulated exocytosis |
GO_0060100 | Biological process | positive regulation of phagocytosis, engulfment |
GO_0043001 | Biological process | Golgi to plasma membrane protein transport |
GO_0030667 | Cellular component | secretory granule membrane |
GO_0005886 | Cellular component | plasma membrane |
GO_0012505 | Cellular component | endomembrane system |
GO_0005769 | Cellular component | early endosome |
GO_0031901 | Cellular component | early endosome membrane |
GO_0036186 | Cellular component | early phagosome membrane |
GO_0032588 | Cellular component | trans-Golgi network membrane |
GO_0005829 | Cellular component | cytosol |
GO_0045335 | Cellular component | phagocytic vesicle |
GO_0001891 | Cellular component | phagocytic cup |
GO_0019003 | Molecular function | GDP binding |
GO_0005525 | Molecular function | GTP binding |
GO_0005515 | Molecular function | protein binding |
GO_0003924 | Molecular function | GTPase activity |
Gene name | RAB31 |
Protein name | RAB31, member RAS oncogene family Ras-related protein Rab-31 (Ras-related protein Rab-22B) |
Synonyms | RAB22B |
Description | FUNCTION: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Required for the integrity and for normal function of the Golgi apparatus and the trans-Golgi network. Plays a role in insulin-stimulated translocation of GLUT4 to the cell membrane. Plays a role in M6PR transport from the trans-Golgi network to endosomes. Plays a role in the internalization of EGFR from the cell membrane into endosomes. Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. . |
Accessions | J3QR51 J3KRU3 ENST00000581109.1 ENST00000578734.5 ENST00000583137.1 ENST00000578921.6 Q13636 J3KSM8 |