I. Related cell sub types
ID | Name | Number of studies  | |
|---|---|---|---|
| CL_0002138 | endothelial cell of lymphatic vessel | 41 | |
| CL_0002139 | endothelial cell of vascular tree | 21 |
ID | Name | Number of studies | |
|---|---|---|---|
| CL_0002138 | endothelial cell of lymphatic vessel | 41 | |
| CL_0002139 | endothelial cell of vascular tree | 21 |
Gene | Number of supported studies | Average coverage | Other major groups (express this gene) | Other cell types (express this gene) | |
|---|---|---|---|---|---|
| CCL21 | 30 | 81% ± 22% | 0 | 1 | |
| TIE1 | 23 | 41% ± 18% | 0 | 6 | |
| KANK3 | 22 | 46% ± 14% | 0 | 6 | |
| TBX1 | 21 | 42% ± 15% | 0 | 0 | |
| FLT4 | 21 | 44% ± 15% | 0 | 3 | |
| ECSCR | 20 | 66% ± 25% | 0 | 6 | |
| TMEM255B | 18 | 30% ± 13% | 0 | 5 | |
| F8 | 18 | 29% ± 10% | 0 | 7 | |
| MMRN1 | 29 | 79% ± 13% | 1 | 6 | |
| DIPK2B | 21 | 42% ± 11% | 1 | 6 | |
| CDH5 | 21 | 34% ± 12% | 1 | 8 | |
| RELN | 21 | 44% ± 17% | 1 | 9 | |
| ROBO4 | 19 | 28% ± 8% | 1 | 8 | |
| MYCT1 | 18 | 32% ± 12% | 1 | 8 | |
| LYVE1 | 27 | 51% ± 18% | 2 | 8 | |
| RAMP2 | 23 | 70% ± 22% | 2 | 12 | |
| CALCRL | 23 | 51% ± 16% | 2 | 14 | |
| RHOJ | 22 | 49% ± 18% | 2 | 9 | |
| TNXB | 19 | 34% ± 10% | 2 | 8 | |
| CLDN5 | 27 | 74% ± 20% | 3 | 10 | |
| ANGPT2 | 25 | 41% ± 16% | 3 | 13 | |
| HYAL2 | 22 | 52% ± 21% | 3 | 10 | |
| FABP4 | 22 | 51% ± 22% | 3 | 13 | |
| PGM5 | 20 | 46% ± 20% | 3 | 9 | |
| PROX1 | 26 | 57% ± 18% | 4 | 15 | |
| TM4SF1 | 28 | 65% ± 26% | 4 | 35 | |
| LAMA4 | 23 | 53% ± 17% | 4 | 21 | |
| PLSCR4 | 22 | 41% ± 16% | 4 | 16 | |
| SEMA3A | 21 | 41% ± 20% | 4 | 20 | |
| OAF | 20 | 33% ± 11% | 4 | 12 |
| GO_0050819 | Biological process | negative regulation of coagulation |
| GO_0001771 | Biological process | immunological synapse formation |
| GO_1990086 | Biological process | lens fiber cell apoptotic process |
| GO_0070858 | Biological process | negative regulation of bile acid biosynthetic process |
| GO_0060838 | Biological process | lymphatic endothelial cell fate commitment |
| GO_1990428 | Biological process | miRNA transport |
| GO_0031529 | Biological process | ruffle organization |
| GO_0060836 | Biological process | lymphatic endothelial cell differentiation |
| GO_1903142 | Biological process | positive regulation of establishment of endothelial barrier |
| GO_0021516 | Biological process | dorsal spinal cord development |
| GO_0038116 | Biological process | chemokine (C-C motif) ligand 21 signaling pathway |
| GO_0030910 | Biological process | olfactory placode formation |
| GO_0002693 | Biological process | positive regulation of cellular extravasation |
| GO_0060214 | Biological process | endocardium formation |
| GO_0060421 | Biological process | positive regulation of heart growth |
| GO_0048664 | Biological process | neuron fate determination |
| GO_0060042 | Biological process | retina morphogenesis in camera-type eye |
| GO_0070309 | Biological process | lens fiber cell morphogenesis |
| GO_0048644 | Biological process | muscle organ morphogenesis |
| GO_0034695 | Biological process | response to prostaglandin E |
| GO_0072574 | Biological process | hepatocyte proliferation |
| GO_0061099 | Biological process | negative regulation of protein tyrosine kinase activity |
| GO_0060414 | Biological process | aorta smooth muscle tissue morphogenesis |
| GO_1903237 | Biological process | negative regulation of leukocyte tethering or rolling |
| GO_0097490 | Biological process | sympathetic neuron projection extension |
| GO_0042592 | Biological process | homeostatic process |
| GO_0021707 | Biological process | cerebellar granule cell differentiation |
| GO_0001945 | Biological process | lymph vessel development |
| GO_2000669 | Biological process | negative regulation of dendritic cell apoptotic process |
| GO_0030240 | Biological process | skeletal muscle thin filament assembly |
| Cell type name | endothelial cell of lymphatic vessel |
| Synonyms | LEC lymphatic endothelial cell |
| Description | A endothelial cell of a lymphatic vessel. The border of the oak leaf-shaped endothelial cell of initial lymphatics are joined by specialized buttons. The discontinuous feature of buttons distinguishes them from zippers in collecting lymphatics, but both types of junctions are composed of proteins typical of adherens junctions and tight junctions found in the endothelium of blood vessels. Buttons seal the sides of flaps of the oak leaf-shaped endothelial cell, leaving open the tips of flaps as routes for fluid entry without disassembly and reformation of intercellular junctions. |
| Parent | CL_0002139 |
