CLDN5 | OmnibusX

I. Expression across cell types

Name	Number of supported studies	Average coverage
endothelial cell	49 studies	56% ± 23%	Explore
endothelial cell of lymphatic vessel	27 studies	74% ± 20%	Explore
capillary endothelial cell	18 studies	63% ± 24%	Explore
endothelial cell of artery	16 studies	68% ± 25%	Explore
vein endothelial cell	15 studies	60% ± 24%	Explore
endothelial cell of vascular tree	14 studies	55% ± 17%	Explore
platelet	9 studies	28% ± 10%	Explore
pericyte	6 studies	39% ± 17%	Explore
glomerular endothelial cell	4 studies	40% ± 8%	Explore
podocyte	3 studies	64% ± 9%	Explore
endothelial cell of sinusoid	3 studies	52% ± 22%	Explore

II. Expression across tissues

Name	Number of supported studies	Average coverage
lung	3 studies	23% ± 6%	Explore

Tissue	GTEx Coverage	GTEx Average TPM	GTEx Number of samples	TCGA Coverage	TCGA Average TPM	TCGA Number of samples
brain	95%	5878.72	2501 / 2642	100%	92.63	705 / 705
thymus	98%	7999.90	641 / 653	95%	24.11	573 / 605
lung	100%	24840.82	578 / 578	85%	19.00	977 / 1155
prostate	74%	2896.93	181 / 245	89%	15.59	446 / 502
bladder	95%	6009.76	20 / 21	63%	10.53	315 / 504
breast	100%	25889.23	458 / 459	58%	9.96	644 / 1118
esophagus	82%	4214.03	1183 / 1445	69%	12.23	126 / 183
uterus	97%	6577.48	165 / 170	53%	10.87	242 / 459
intestine	87%	4179.44	841 / 966	58%	8.06	306 / 527
kidney	63%	1837.62	56 / 89	78%	19.61	706 / 901
stomach	48%	1619.94	174 / 359	64%	10.55	183 / 286
skin	65%	3736.93	1175 / 1809	38%	5.02	177 / 472
pancreas	9%	287.45	29 / 328	93%	24.38	165 / 178
adipose	100%	22999.21	1204 / 1204	0%	0	0 / 0
ureter	0%	0	0 / 0	100%	6.10	1 / 1
adrenal gland	12%	305.71	30 / 258	87%	20.09	200 / 230
lymph node	0%	0	0 / 0	90%	20.68	26 / 29
ovary	47%	1743.63	84 / 180	43%	5.05	183 / 430
liver	4%	123.14	8 / 226	82%	17.60	332 / 406
muscle	80%	3342.83	640 / 803	0%	0	0 / 0
spleen	76%	2508.64	182 / 241	0%	0	0 / 0
tonsil	0%	0	0 / 0	71%	7.54	32 / 45
eye	0%	0	0 / 0	55%	5.02	44 / 80
heart	50%	2196.21	432 / 861	0%	0	0 / 0
blood vessel	48%	2211.47	644 / 1335	0%	0	0 / 0
peripheral blood	0%	9.91	4 / 929	0%	0	0 / 0
abdomen	0%	0	0 / 0	0%	0	0 / 0
bone marrow	0%	0	0 / 0	0%	0	0 / 0
diaphragm	0%	0	0 / 0	0%	0	0 / 0
gingiva	0%	0	0 / 0	0%	0	0 / 0
nasal cavity	0%	0	0 / 0	0%	0	0 / 0
nasopharynx	0%	0	0 / 0	0%	0	0 / 0
nose	0%	0	0 / 0	0%	0	0 / 0
placenta	0%	0	0 / 0	0%	0	0 / 0
spinal column	0%	0	0 / 0	0%	0	0 / 0

III. Associated gene sets

GO_0007043	Biological process	cell-cell junction assembly
GO_0003151	Biological process	outflow tract morphogenesis
GO_1990963	Biological process	establishment of blood-retinal barrier
GO_0042552	Biological process	myelination
GO_0010629	Biological process	negative regulation of gene expression
GO_0007612	Biological process	learning
GO_1903142	Biological process	positive regulation of establishment of endothelial barrier
GO_0043116	Biological process	negative regulation of vascular permeability
GO_0032092	Biological process	positive regulation of protein binding
GO_0010628	Biological process	positive regulation of gene expression
GO_0007155	Biological process	cell adhesion
GO_1903348	Biological process	positive regulation of bicellular tight junction assembly
GO_0045471	Biological process	response to ethanol
GO_0016338	Biological process	calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules
GO_0016525	Biological process	negative regulation of angiogenesis
GO_0060021	Biological process	roof of mouth development
GO_0070830	Biological process	bicellular tight junction assembly
GO_0035633	Biological process	maintenance of blood-brain barrier
GO_0008284	Biological process	positive regulation of cell population proliferation
GO_0030336	Biological process	negative regulation of cell migration
GO_0060325	Biological process	face morphogenesis
GO_0007179	Biological process	transforming growth factor beta receptor signaling pathway
GO_0120192	Biological process	tight junction assembly
GO_0070160	Cellular component	tight junction
GO_0005886	Cellular component	plasma membrane
GO_0016020	Cellular component	membrane
GO_0030864	Cellular component	cortical actin cytoskeleton
GO_0005911	Cellular component	cell-cell junction
GO_0043220	Cellular component	Schmidt-Lanterman incisure
GO_0033270	Cellular component	paranode region of axon
GO_0016328	Cellular component	lateral plasma membrane
GO_0005923	Cellular component	bicellular tight junction
GO_0030054	Cellular component	cell junction
GO_0016327	Cellular component	apicolateral plasma membrane
GO_0042802	Molecular function	identical protein binding
GO_0005198	Molecular function	structural molecule activity
GO_0005515	Molecular function	protein binding

Gene name	CLDN5
Protein name	Claudin 5 Claudin-5 (Transmembrane protein deleted in VCFS) (TMDVCF)
Synonyms	AWAL TMVCF hCG_17893
Description	FUNCTION: Plays a major role in tight junction-specific obliteration of the intercellular space. .
Accessions	ENST00000413119.2 ENST00000403084.1 D3DX19 ENST00000618236.2 O00501 ENST00000406028.1

CLDN5 report

I. Expression across cell types

II. Expression across tissues

III. Associated gene sets

IV. Literature review