transforming growth factor beta receptor signaling pathway

I. Involved cell-cell interactions

[source]
Interactors
Protein name
Directionality
Classification
1COL1A2-ITGA10+ITGB1CO1A2_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
2COL1A2-ITGA11+ITGB1CO1A2_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
3COL1A2-ITGA1+ITGB1CO1A2_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
4COL1A2-ITGA2+ITGB1CO1A2_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
5COL3A1-ITGA10+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
6COL3A1-ITGA11+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
7COL3A1-ITGA1+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
8COL3A1-ITGA2+ITGB1CO3A1_HUMAN - Adhesion-AdhesionAdhesion by Collagen/Integrin
9GDF5-ACVR2A+BMPR1AGDF5_HUMAN - Ligand-ReceptorSignaling by Growth differentiation factor
10GDF5-ACVR2B+BMPR1AGDF5_HUMAN - Ligand-ReceptorSignaling by Growth differentiation factor
11GDF9-BMPR2+TGFBR1GDF9_HUMAN - Ligand-ReceptorSignaling by Growth differentiation factor
12MSTN-ACVR2A+TGFBR1GDF8_HUMAN - Ligand-ReceptorSignaling by Growth differentiation factor
13MSTN-ACVR2B+TGFBR1GDF8_HUMAN - Ligand-ReceptorSignaling by Growth differentiation factor
14TGFB1-ACVR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
15TGFB1-ITGAV+ITGB6TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
16TGFB1-TGFBR1+TGFBR2TGFB1_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
17TGFB1-TGFBR3TGFB1_HUMAN - TGBR3_HUMANLigand-ReceptorSignaling by Transforming growth factor
18TGFB2-ACVR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
19TGFB2-TGFBR1+TGFBR2TGFB2_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
20TGFB2-TGFBR3TGFB2_HUMAN - TGBR3_HUMANLigand-ReceptorSignaling by Transforming growth factor
21TGFB3-ACVR1+TGFBR2TGFB3_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
22TGFB3-ITGAV+ITGB6TGFB3_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
23TGFB3-ITGAV+ITGB8TGFB3_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
24TGFB3-TGFBR1+TGFBR2TGFB3_HUMAN - Ligand-ReceptorSignaling by Transforming growth factor
25TGFB3-TGFBR3TGFB3_HUMAN - TGBR3_HUMANLigand-ReceptorSignaling by Transforming growth factor

II. Literature review

[source]
Nametransforming growth factor beta receptor signaling pathway
IDGO_0007179
collection_id

Biological process

Exact synonym

TGF-beta receptor signaling pathway, TGF-beta receptor signalling pathway, TGFbeta receptor signaling pathway, TGFbeta receptor signalling pathway, transforming growth factor beta receptor signalling pathway

Description

The series of molecular signals initiated by an extracellular ligand binding to a transforming growth factor beta receptor on the surface of a target cell, and ending with the regulation of a downstream cellular process, e.g. transcription.

External URL
Genes
ID1ENGLEFTY1PARP1ITGA8LTBP3PMLSMAD4NRROSDUSP22smad2_3-smad4_humanDAB2tgfb3-tgfbr1-tgfbr2_humanLTBP4ZFYVE9CITED1CAV2SKILFERMT2tgfb2_human-1tgfb1-tgfbr1-tgfbr2_humanCITED2TGFBRAP1SIRT1TGFBR1CDH5COL3A1FOSPTK2ZMIZ1COL1A2HPGDCLDN5USP9YFOXH1ACVRL1TGFB3ADAM9tgfb1_human-1URS00001D6BAE_9606FLCNSTAT3GDF10SRCURS0000528CBC_9606AMHR2ARRB2NDPTAB1TGFB1BMPR1APXNFURINtgfb2-tgfbr1-tgfbr2_humanTGFB2HIPK2PSG9SMAD2FSHBITGB8ACVR1SMAD1USP9XCHST11TP53ITGB1ONECUT1ONECUT2APPL2tgfb3_human-1URS000019B0F7_9606WFIKKN2LRRC32LTBP2FUT8GLG1BAMBIAPPL1SMAD5LPXNITGB6SKIPTPRKURS0000065D58_9606ZMIZ2SMAD7GDF5TGFBR3LMSTNSMAD3TGFBR3APOA1JUNMAP3K7NLKSMAD9GDF9TGFBR2FNTAWFIKKN1USP15NPNTGCNT2ZYXNODALGDF15SMAD6ITGB5smad1-smad4_human