WFIKKN2 report

I. Expression across cell types

Insufficient scRNA-seq data for expression of WFIKKN2 at single-cell level.

II. Expression across tissues

sc-RNAseq data

Insufficient scRNA-seq data for expression of WFIKKN2 at tissue level.

III. Associated gene sets

GO_0001501Biological processskeletal system development
GO_0060021Biological processroof of mouth development
GO_0007179Biological processtransforming growth factor beta receptor signaling pathway
GO_0030512Biological processnegative regulation of transforming growth factor beta receptor signaling pathway
GO_0055001Biological processmuscle cell development
GO_0005615Cellular componentextracellular space
GO_0048019Molecular functionreceptor antagonist activity
GO_0050431Molecular functiontransforming growth factor beta binding
GO_0004867Molecular functionserine-type endopeptidase inhibitor activity
GO_0005515Molecular functionprotein binding

IV. Literature review

[source]
Gene nameWFIKKN2
Protein nameWAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
WAP, Kazal, immunoglobulin, Kunitz and NTR domain-containing protein 2 (Growth and differentiation factor-associated serum protein 1) (GASP-1) (hGASP-1) (WAP, follistatin, immunoglobulin, Kunitz and NTR domain-containing-related protein) (WFIKKN-related protein)
SynonymsGASP1
WFIKKNRP
UNQ9235/PRO31996
DescriptionFUNCTION: Protease-inhibitor that contains multiple distinct protease inhibitor domains. Probably has serine protease- and metalloprotease-inhibitor activity. Inhibits the biological activity of mature myostatin, but not activin (By similarity). .

AccessionsQ8TEU8
C9J6G4
ENST00000426127.1
ENST00000311378.5