Name | Number of supported studies | Average coverage | |
---|---|---|---|
astrocyte | 19 studies | 40% ± 17% | |
oligodendrocyte precursor cell | 15 studies | 48% ± 17% | |
oligodendrocyte | 14 studies | 38% ± 17% | |
ciliated cell | 11 studies | 35% ± 18% | |
basal cell | 11 studies | 25% ± 9% | |
epithelial cell | 7 studies | 43% ± 24% | |
macrophage | 6 studies | 24% ± 12% | |
secretory cell | 6 studies | 25% ± 5% | |
respiratory goblet cell | 5 studies | 22% ± 4% | |
glutamatergic neuron | 5 studies | 29% ± 12% | |
neuron | 4 studies | 26% ± 13% | |
retinal pigment epithelial cell | 4 studies | 69% ± 16% | |
mesothelial cell | 4 studies | 41% ± 21% | |
squamous epithelial cell | 3 studies | 63% ± 13% | |
GABAergic neuron | 3 studies | 30% ± 5% | |
rod bipolar cell | 3 studies | 30% ± 9% | |
neural progenitor cell | 3 studies | 40% ± 10% | |
ependymal cell | 3 studies | 66% ± 18% | |
enteroendocrine cell | 3 studies | 19% ± 3% | |
Schwann cell | 3 studies | 40% ± 14% | |
parietal epithelial cell | 3 studies | 57% ± 10% | |
podocyte | 3 studies | 76% ± 3% | |
renal principal cell | 3 studies | 21% ± 3% | |
mucus secreting cell | 3 studies | 26% ± 8% | |
epithelial cell of proximal tubule | 3 studies | 22% ± 4% | |
kidney loop of Henle epithelial cell | 3 studies | 21% ± 3% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
ovary | 99% | 1492.39 | 178 / 180 | 97% | 36.43 | 418 / 430 |
brain | 96% | 3503.88 | 2532 / 2642 | 99% | 51.52 | 695 / 705 |
esophagus | 99% | 2049.16 | 1427 / 1445 | 94% | 30.76 | 172 / 183 |
kidney | 100% | 5211.93 | 89 / 89 | 90% | 68.28 | 814 / 901 |
pancreas | 93% | 1387.07 | 304 / 328 | 86% | 13.99 | 153 / 178 |
uterus | 99% | 1947.42 | 169 / 170 | 76% | 14.97 | 348 / 459 |
lung | 76% | 949.35 | 441 / 578 | 70% | 15.33 | 814 / 1155 |
prostate | 100% | 2740.90 | 245 / 245 | 46% | 4.40 | 229 / 502 |
bladder | 100% | 2990.43 | 21 / 21 | 45% | 6.52 | 226 / 504 |
intestine | 93% | 1337.54 | 903 / 966 | 49% | 6.13 | 258 / 527 |
thymus | 88% | 883.48 | 572 / 653 | 55% | 6.40 | 331 / 605 |
stomach | 64% | 697.80 | 230 / 359 | 62% | 8.47 | 177 / 286 |
skin | 76% | 1749.13 | 1370 / 1809 | 46% | 13.49 | 219 / 472 |
breast | 66% | 1943.63 | 304 / 459 | 51% | 8.71 | 575 / 1118 |
adrenal gland | 51% | 440.29 | 132 / 258 | 43% | 3.86 | 98 / 230 |
tonsil | 0% | 0 | 0 / 0 | 89% | 22.40 | 40 / 45 |
adipose | 56% | 1010.14 | 674 / 1204 | 0% | 0 | 0 / 0 |
blood vessel | 47% | 693.71 | 629 / 1335 | 0% | 0 | 0 / 0 |
heart | 43% | 487.90 | 366 / 861 | 0% | 0 | 0 / 0 |
peripheral blood | 16% | 269.43 | 145 / 929 | 0% | 0 | 0 / 0 |
liver | 1% | 5.42 | 2 / 226 | 10% | 1.73 | 41 / 406 |
eye | 0% | 0 | 0 / 0 | 9% | 0.77 | 7 / 80 |
muscle | 1% | 7.51 | 7 / 803 | 0% | 0 | 0 / 0 |
spleen | 0% | 2.63 | 1 / 241 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0033627 | Biological process | cell adhesion mediated by integrin |
GO_0010629 | Biological process | negative regulation of gene expression |
GO_0001573 | Biological process | ganglioside metabolic process |
GO_0045766 | Biological process | positive regulation of angiogenesis |
GO_0007160 | Biological process | cell-matrix adhesion |
GO_0009615 | Biological process | response to virus |
GO_0010628 | Biological process | positive regulation of gene expression |
GO_0001570 | Biological process | vasculogenesis |
GO_0007155 | Biological process | cell adhesion |
GO_0006955 | Biological process | immune response |
GO_0007229 | Biological process | integrin-mediated signaling pathway |
GO_0060674 | Biological process | placenta blood vessel development |
GO_0060022 | Biological process | hard palate development |
GO_0098609 | Biological process | cell-cell adhesion |
GO_0007179 | Biological process | transforming growth factor beta receptor signaling pathway |
GO_0051216 | Biological process | cartilage development |
GO_0016477 | Biological process | cell migration |
GO_0061520 | Biological process | Langerhans cell differentiation |
GO_0005886 | Cellular component | plasma membrane |
GO_0008305 | Cellular component | integrin complex |
GO_0070062 | Cellular component | extracellular exosome |
GO_0005925 | Cellular component | focal adhesion |
GO_0034686 | Cellular component | integrin alphav-beta8 complex |
GO_0009986 | Cellular component | cell surface |
GO_1990430 | Molecular function | extracellular matrix protein binding |
GO_0005178 | Molecular function | integrin binding |
GO_0046872 | Molecular function | metal ion binding |
Gene name | ITGB8 |
Protein name | Integrin beta Integrin beta-8 |
Synonyms | hCG_37311 |
Description | FUNCTION: Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin . It recognizes the sequence R-G-D in its ligands . Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor beta-1 (TGF-beta-1) from regulatory Latency-associated peptide (LAP), thereby playing a key role in TGF-beta-1 activation on the surface of activated regulatory T-cells (Tregs) (Probable). Required during vasculogenesis (By similarity). . |
Accessions | P26012 ENST00000537992.5 [P26012-2] Q9BUG9 ENST00000222573.5 [P26012-1] |