renal principal cell report

I. Related cell sub types

II. Gene markers

Gene
Number of
supported studies
Average coverage
Other major groups
(express this gene)
Other cell types
(express this gene)
AQP2558% ± 22%00
FXYD4551% ± 30%00
CDH16560% ± 33%05
SLC9A4423% ± 0%00
EMX1437% ± 18%01
CCDC198438% ± 9%05
ATP6V0A4422% ± 4%05
SIM1323% ± 6%01
TMEM72319% ± 4%02
CYS1324% ± 5%02
TMEM213353% ± 11%04
WDR72348% ± 20%04
CLCNKB337% ± 14%05
PTGER3535% ± 12%16
HSD11B2577% ± 12%17
SCNN1G451% ± 4%11
DEFB1557% ± 29%113
PAX2437% ± 5%14
CALB1432% ± 13%14
KCNJ16464% ± 8%15
PAX8474% ± 12%17
LHX1323% ± 6%12
TFCP2L1440% ± 7%112
PIGQ330% ± 9%13
SCIN556% ± 10%210
KCNJ15434% ± 8%25
PKHD1463% ± 36%25
PAPPA443% ± 15%27
ARG2447% ± 16%28
SCNN1B442% ± 21%28

III. Associated gene sets

GO_0060231Biological processmesenchymal to epithelial transition
GO_0071288Biological processcellular response to mercury ion
GO_0015793Biological processglycerol transmembrane transport
GO_0021650Biological processvestibulocochlear nerve formation
GO_0003406Biological processretinal pigment epithelium development
GO_0003097Biological processrenal water transport
GO_0030031Biological processcell projection assembly
GO_0051693Biological processactin filament capping
GO_0050914Biological processsensory perception of salty taste
GO_1904117Biological processcellular response to vasopressin
GO_0050915Biological processsensory perception of sour taste
GO_0072207Biological processmetanephric epithelium development
GO_0021631Biological processoptic nerve morphogenesis
GO_0045622Biological processregulation of T-helper cell differentiation
GO_0042989Biological processsequestering of actin monomers
GO_0002520Biological processimmune system development
GO_0072108Biological processpositive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
GO_0032754Biological processpositive regulation of interleukin-5 production
GO_1904045Biological processcellular response to aldosterone
GO_0048646Biological processanatomical structure formation involved in morphogenesis
GO_0035799Biological processureter maturation
GO_1900212Biological processnegative regulation of mesenchymal cell apoptotic process involved in metanephros development
GO_0048793Biological processpronephros development
GO_0072179Biological processnephric duct formation
GO_0051047Biological processpositive regulation of secretion
GO_0007501Biological processmesodermal cell fate specification
GO_0042631Biological processcellular response to water deprivation
GO_0030856Biological processregulation of epithelial cell differentiation
GO_0003337Biological processmesenchymal to epithelial transition involved in metanephros morphogenesis
GO_0071599Biological processotic vesicle development

IV. Literature review

[source]
Cell type namerenal principal cell
Synonyms
DescriptionA cuboidal epithelial cell of the kidney which regulates sodium and potassium balance. The activity of sodium and potassium channels on the apical membrane of the cell is regulated by aldosterone and vasopressin. In mammals this cell type is located in the renal collecting duct system.
ParentCL_0000075