Name | Number of supported studies | Average coverage | |
---|---|---|---|
epithelial cell | 10 studies | 37% ± 22% | |
kidney loop of Henle epithelial cell | 8 studies | 70% ± 31% | |
basal cell | 7 studies | 38% ± 16% | |
kidney connecting tubule epithelial cell | 5 studies | 86% ± 22% | |
renal alpha-intercalated cell | 5 studies | 80% ± 6% | |
kidney distal convoluted tubule epithelial cell | 5 studies | 72% ± 34% | |
renal principal cell | 5 studies | 57% ± 29% | |
duct epithelial cell | 4 studies | 39% ± 25% | |
brush cell | 4 studies | 35% ± 21% | |
secretory cell | 4 studies | 19% ± 3% | |
mucus secreting cell | 3 studies | 49% ± 18% | |
epithelial cell of proximal tubule | 3 studies | 23% ± 10% | |
pancreatic ductal cell | 3 studies | 71% ± 4% | |
keratinocyte | 3 studies | 39% ± 18% |
Tissue | GTEx Coverage | GTEx Average TPM | GTEx Number of samples | TCGA Coverage | TCGA Average TPM | TCGA Number of samples |
---|---|---|---|---|---|---|
kidney | 100% | 20526.71 | 89 / 89 | 88% | 1669.08 | 792 / 901 |
pancreas | 100% | 5989.16 | 328 / 328 | 84% | 394.54 | 150 / 178 |
liver | 98% | 1841.71 | 221 / 226 | 76% | 1019.64 | 308 / 406 |
esophagus | 39% | 919.75 | 565 / 1445 | 44% | 93.86 | 80 / 183 |
skin | 72% | 1940.51 | 1304 / 1809 | 6% | 13.15 | 26 / 472 |
prostate | 60% | 515.11 | 148 / 245 | 16% | 16.38 | 79 / 502 |
ovary | 0% | 0 | 0 / 180 | 63% | 260.99 | 269 / 430 |
bladder | 29% | 135.81 | 6 / 21 | 30% | 82.04 | 150 / 504 |
uterus | 6% | 71.16 | 11 / 170 | 51% | 189.93 | 236 / 459 |
stomach | 39% | 223.13 | 139 / 359 | 16% | 26.71 | 46 / 286 |
tonsil | 0% | 0 | 0 / 0 | 53% | 133.91 | 24 / 45 |
breast | 41% | 494.69 | 186 / 459 | 12% | 36.54 | 133 / 1118 |
intestine | 22% | 122.82 | 212 / 966 | 16% | 42.27 | 84 / 527 |
lung | 3% | 15.26 | 20 / 578 | 27% | 75.65 | 313 / 1155 |
adipose | 14% | 65.95 | 163 / 1204 | 0% | 0 | 0 / 0 |
thymus | 1% | 20.92 | 8 / 653 | 4% | 9.12 | 23 / 605 |
muscle | 1% | 10.79 | 12 / 803 | 0% | 0 | 0 / 0 |
peripheral blood | 1% | 4.05 | 7 / 929 | 0% | 0 | 0 / 0 |
adrenal gland | 0% | 11.38 | 1 / 258 | 0% | 0 | 0 / 230 |
brain | 0% | 0.88 | 7 / 2642 | 0% | 0 | 0 / 705 |
heart | 0% | 0.74 | 2 / 861 | 0% | 0 | 0 / 0 |
blood vessel | 0% | 2.80 | 2 / 1335 | 0% | 0 | 0 / 0 |
abdomen | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
bone marrow | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
diaphragm | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
eye | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 80 |
gingiva | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
lymph node | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 29 |
nasal cavity | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nasopharynx | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
nose | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
placenta | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spinal column | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 0 |
spleen | 0% | 0 | 0 / 241 | 0% | 0 | 0 / 0 |
ureter | 0% | 0 | 0 / 0 | 0% | 0 | 0 / 1 |
GO_0019722 | Biological process | calcium-mediated signaling |
GO_0045087 | Biological process | innate immune response |
GO_0019731 | Biological process | antibacterial humoral response |
GO_0009617 | Biological process | response to bacterium |
GO_0050829 | Biological process | defense response to Gram-negative bacterium |
GO_0060474 | Biological process | positive regulation of flagellated sperm motility involved in capacitation |
GO_0006935 | Biological process | chemotaxis |
GO_0006955 | Biological process | immune response |
GO_0007186 | Biological process | G protein-coupled receptor signaling pathway |
GO_0050830 | Biological process | defense response to Gram-positive bacterium |
GO_0042742 | Biological process | defense response to bacterium |
GO_0061844 | Biological process | antimicrobial humoral immune response mediated by antimicrobial peptide |
GO_0002227 | Biological process | innate immune response in mucosa |
GO_0005615 | Cellular component | extracellular space |
GO_0005576 | Cellular component | extracellular region |
GO_0016020 | Cellular component | membrane |
GO_1990742 | Cellular component | microvesicle |
GO_0005796 | Cellular component | Golgi lumen |
GO_0070062 | Cellular component | extracellular exosome |
GO_0097225 | Cellular component | sperm midpiece |
GO_0042802 | Molecular function | identical protein binding |
GO_0005515 | Molecular function | protein binding |
GO_0031731 | Molecular function | CCR6 chemokine receptor binding |
Gene name | DEFB1 |
Protein name | Beta-defensin 1 (BD-1) (hBD-1) (Defensin, beta 1) |
Synonyms | BD1 HBD1 |
Description | FUNCTION: Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility . . |
Accessions | ENST00000642865.2 P60022 ENST00000297439.4 |