GO_0045087 | OmnibusX

innate immune response

I. Involved cell-cell interactions

	Interactors	Protein name	Directionality	Classification
1	BST2-LILRA4	BST2_HUMAN - LIRA4_HUMAN	Ligand-Receptor
2	CD160-TNFRSF14	BY55_HUMAN - TNR14_HUMAN	Adhesion-Adhesion	Signaling by Tumor necrosis factor
3	CSF1-CSF1R	CSF1_HUMAN - CSF1R_HUMAN	Ligand-Receptor	Signaling by Colony-Stimulating factor
4	FGA+FGB+FGG-ITGAM+ITGB2	-	Ligand-Receptor	Adhesion by Fibribogen
5	IL17A+IL17F-IL17RA+IL17RC	-	Ligand-Receptor	Signaling by Interleukin
6	IL17F-IL17RA+IL17RC	IL17F_HUMAN -	Ligand-Receptor	Signaling by Interleukin
7	IL34-CSF1R	IL34_HUMAN - CSF1R_HUMAN	Ligand-Receptor	Signaling by Interleukin
8	IL36A-IL1RAP+IL1RL2	IL36A_HUMAN -	Ligand-Receptor	Signaling by Interleukin
9	IL36B-IL1RAP+IL1RL2	IL36B_HUMAN -	Ligand-Receptor	Signaling by Interleukin
10	IL36G-IL1RAP+IL1RL2	IL36G_HUMAN -	Ligand-Receptor	Signaling by Interleukin
11	IL36RN-IL1RAP+IL1RL2	I36RA_HUMAN -	Ligand-Receptor	Signaling by Interleukin
12	RNASET2-TLR8	RNT2_HUMAN - TLR8_HUMAN	Ligand-Receptor

II. Literature review

Name	innate immune response
ID	GO_0045087
collection_id	Biological process
Alternative ID	GO:0002226
Exact synonym	innate immunity, nonspecific immune response
Description	Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
External URL
Genes	G3BP2 TRGV3 GARIN5A sting_human-1 TRIM40 PSPC1 DEFB134 MFHAS1 TRIM6 IFI27 IPO7 TRIM27 RBM14 TRIM64C OTULIN LY9 TRIM58 IRF3 ADAM15 tlr1_tlr2_human JCHAIN CD1D DEFB106A CAMP TASL BPIFC IFNL1 WFDC10B CLEC7A ITGAM TICAM1 PTK6 C6 TRIM43B PELI3 TBK1 TRGV4 NONO BPIFB3 UBE2L6 WFDC2 IFNL2 G3BP1 SRC NLRC5 GZMM CD180 TICAM2 IFNB1 TRIML2 NLRC4 CD244 NFKB2 DDX21 ISG20 ATP1B1 TRIM13 CYBC1 SLPI tlr4_tlr6_human MX1 C1QB IL17A AKIRIN2 TRIM21 USP29 RNASE8 OTUD4 HMGB1 SAMD9 CX3CR1 C1RL WFDC3 DEFB104A TRIM51 SRPK2 MIF APOBEC3G CD46 CSF1 APCS URS000050B527_9606 LILRA4 TTLL12 NFKB1 GSDMD PRKD1 TRIM34 PSTPIP1 ZNFX1 RIGI TMEM33 S100A12 TIFA STMP1 SERINC3 TNFRSF14 UBA7 TRIM25 POLR3H TRIM51G TRIM23 IL36B MAP4K2 DEFB118 CLEC6A DEFB112 MCOLN2 SLAMF6 MYD88 CACTIN TRIM11 HMGB3 ARHGEF2 PGLYRP4 LILRA5 TRIM56 TRIM14 IL17F TOLLIP MST1R KLRC1 WFDC11 C4B POLR3C S100A8 USP14 C4BPB IRGM SHFL ENDOD1 INAVA ITCH DEFB1 TRIM59 PYCARD ILRUN STING1 IKBKB APOBEC3C FYN IKBKG OPTN ADARB1 HMGB2 LBP DEFA4 FCER1G ANG LYAR WFDC13 CLU OAS3 TRIM26 AKAP8 JAK3 SMPDL3B DEFB131B SIGLEC10 NLRP3 AIM2 DDX60 RSAD2 DHX9 TLR1 CFI MMP3 DEFB116 HLA-C SYK IRF7 IFNL4 LCK HLA-A GBP1 CD209 NLRP2B NAGK ZBTB1 CASP4 CLEC4E ANKRD17 PPARG FGR DEFB121 DEFB131A IFI6 TLR10 PIK3CD BCL10 ARG2 NEURL3 TREM1 DEFB115 LCN2 CORO1A RFPL4A TRIM43 DEFB108B TRIL TRIM64B CLEC4M MID2 IL1RL2 IFIH1 MEFV ZCCHC3 TLR6 TRIM48 PLA2G2F UNC93B1 HEXIM1 DEFB124 SAMHD1 SEC14L1 BPI NLRP2 WFDC9 YTHDF2 MATR3 NEDD4 TLR9 PIK3CG CD84 TIRAP C1QC CLEC5A UBL7 DEFB105A OASL DEFB132 MAVS TRIM28 APOBEC3A SH2D1B ZC3HAV1 TNFAIP8L2 ALPK1 TRAF4 IL36A TRIM49C TRDV2 FOSL2 CGAS CYBA WFDC12 SLAMF1 TRGV8 TRIM8 TLR7 TLR2 TRIM5 NMI POLR3K RNASE3 SSC5D SMIM30 PJA2 PARP1 NCF1 PML FGA XRCC6 NRROS C1R METTL3 TRIM68 LGALS3 WFDC10A TREML1 PLD4 NR1H4 LGR4 RNASET2 TRGV9 MR1 RNF166 MSRB1 CRP RFPL4AL1 CD6 KLRG1 PPP1R14B SLC15A3 DEFB108A IFIT5 TLR8 TTC4 C1QA TRIM31 HERC5 MBL2 SERPING1 PLPP6 TRIM38 SDHAF4 GP2 IL34 HTN3 HK1 PCBP2 PYDC2 RIPK2 BTK XRCC5 PTX3 DEFA5 DAB2IP DHX36 ZDHHC5 C4A HLA-E POLR3A FRK SERINC5 CRCP RARRES2 FADD USP27X CHUK RFPL2 DEFB125 TRIM32 WRNIP1 LILRA2 RNF135 SLC15A4 GPER1 TRIM35 LY86 DCST1 PARP14 LYN IGHM NAIP CRISP3 TRDV1 SLC46A2 CYLD TMEM43 DEFB114 FCGR1A CCDC92 RNASE6 ZAP70 DDX1 TRIM62 DEFB110 CD14 REL RNASE7 TRIM49 SARM1 TLR4 POLR3B N4BP1 SFPQ NLRP9 CNPY3 TRGV5 APOL1 F12 RFPL1 HLA-B ZDHHC18 C1QBP NLRP10 POLR3E PGLYRP2 TRIM22 CD177 DEFB113 C1S DEFB135 SPIRE1 ADAR FBXO9 tlr2_tlr6_human BPIFA1 MX2 F2RL1 DEFB133 SIRT2 MARCO TRGV2 CHID1 CSF1R TAX1BP1 TRDV3 MALT1 COLEC12 TRIM77 AXL IFI35 TRAF2 IL27 KRT16 IL36RN ANKHD1 CD160 ARG1 PGLYRP1 GATA3 ADGRB1 PARP9 HCK PGLYRP3 IFI16 IL36G TMEM45B PPP6C CHGA TLR3 WFDC5 APOBEC3D SKP2 TRIM29 tlr1_tlr10_human LY96 RELA PQBP1 APOBEC3F DEFB127 TRAF6 ZNF683 IL23A ISG15 CD55 IL1RAP POLR3G PRDM1 SUSD4 TMED1 S100A9 LACC1 DEFB123 NOD1 IRAK1 NLRX1 DEFB128 SPON2 POLR3D HAVCR2 SRPK1 IRAK4 TARM1 MAP3K5 CYBB DEFB107A VNN1 TRIML1 NOD2 PADI4 tlr2_tlr10_human RIOK3 TRIM15 ANXA1 NCF2 TRIM49B PI3 RAB2B TRIM49D1 SFTPD nlgn1-nlgn1 YES1 TLR5 N4BP3 DTX3L CLEC10A BST2 IRF5 PRKDC SRMS RELB IL17RA KAT5 BLK RNF185 IFNL3 HVCN1 DDX3X TREML4 APOBEC3B TRIM64 URS000024B619_9606 TRIM4 TMEM106A TRIM10 RFPL3 ECSIT NQO1 PYDC1 C4BPA ARID5A POLR3F FGB APOBEC3H C2 DMBT1